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24 Cards in this Set
- Front
- Back
Draw the divisions of the Nervous system
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Found on Pg 153
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Sympathetic Nervous system also known as:
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Andregenic
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Parasympathetic nervous system also known as:
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Cholinergic
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(P) non selective andregenic agonist
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(P) epinephrine
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(P) Alpha-1 andregenic agonist
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(P) Phenylephrine
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(P) Alpha-2 Andregenic agonist
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(P) Clonidine
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(P) Beta Andregenic Agonist
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(P) Dopamine
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(P) Dopaminergic agonist
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(P) Fenoldopam
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(P) Alpha-adregenic Antagonist
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(P) Prazosin
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(P) Beta Androgenic Antagonist
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(P) Propranolol
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Neurotransmitters of the ANS
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ACh
NE Epi |
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In SNS, ACh present in: (4)
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1) all preganglionic neurons
2) Postganglionic in PSNS 3) Postganglionic to sweat glands in ANS 4) Motor Neurons in Somatic motor system Pic pg 156 |
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Precursors of ACh?
degraded by? Into what 2 inactive products? OR? |
Choline & Acetyl coenzyme A
ACh-esterase into acetate & choline OR reuptake 2 storage |
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Epinephrine comes from?
What does it do? |
NE that is converted enzymatically in Adrenal medulla
Travels through blood stream to target organs in SNS system |
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3 types of andregenic receptors and their subtypes?
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Alpha (1, 2)
Beta (1, 2) Dopaminergic (1-5) |
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Alpha andregenic receptors types 1 & 2 stimulated by?
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1 - epi, NE, Dop
2- Epi, NE |
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Beta 1 & 2 Andregenic receptors stimulated by?
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1- epi, NE dop
2- Epi (only) |
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Common indication for adregenic agonists? (5 types)?
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shock
1) hypovolemic 2) cardiogenic 3) Septic 4) Obstructive 5) Neurogenic |
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3 examples of indirect stimulation of andregenic receptors?
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1) block reuptake
2) inhibir action of COMT & MAO 3) increasing NE transmission |
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andregenic agonists split into 2 groups? (& characteristics?)
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1) catecholamines (no PO, short duration, administered continuously, do not cross blood-brain)
2) Non-catecholamines (opposite) |
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Nonselective andregenics stimulate all receptors except?
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dopamine receptors
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(P) EPINEPHRINE
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NON-SELECTIVE ADRENERGIC AGONIST
RECEPTOR: A1 A2 B1 B2 PHYSIOLOGICAL AXN(s): vasoconstrict arteries/veins vasodil skel muscle HR up bronchodilation THERAPEUTIC USES: shock (also anaphylactic) asthma CPR glaucoma ADVERSE FX: FREQUENT angina arrhythmias CONTRAS: active labour closed-angle glaucoma gen anethesia *monitor CardioVasc status during* |
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(P) DOPAMINE
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BETA ADRENERGIC AGONIST
RECEPTOR: A1 B1 DOP1/2 PHYSIOLOGICAL AXN(s): up cardiac output up BP up renal perfusion THERAPEUTIC USES: hypOtension from shock ADVERSE FX: angina tachycardia N&V dyspnea hypOtension CONTRAS: pheocromocytoma tachyarrhythmias V fib *monitor BP** |
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(P) FENOLDOPAM
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DOPAMINERGIC AGONIST
RECEPTOR: a2 DOP1/2 PHYSIOLOGICAL AXN(s): periph vasodil THERAPEUTIC USES: hypertension ADVERSE FX: hypOtension tachycardia CONTRAS: sulfite sensitivity *titrate drug slowly* *monitor HR & BP* |