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24 Cards in this Set

  • Front
  • Back
Draw the divisions of the Nervous system
Found on Pg 153
Sympathetic Nervous system also known as:
Andregenic
Parasympathetic nervous system also known as:
Cholinergic
(P) non selective andregenic agonist
(P) epinephrine
(P) Alpha-1 andregenic agonist
(P) Phenylephrine
(P) Alpha-2 Andregenic agonist
(P) Clonidine
(P) Beta Andregenic Agonist
(P) Dopamine
(P) Dopaminergic agonist
(P) Fenoldopam
(P) Alpha-adregenic Antagonist
(P) Prazosin
(P) Beta Androgenic Antagonist
(P) Propranolol
Neurotransmitters of the ANS
ACh
NE
Epi
In SNS, ACh present in: (4)
1) all preganglionic neurons
2) Postganglionic in PSNS
3) Postganglionic to sweat glands in ANS
4) Motor Neurons in Somatic motor system

Pic pg 156
Precursors of ACh?

degraded by?

Into what 2 inactive products? OR?
Choline & Acetyl coenzyme A

ACh-esterase

into acetate & choline OR reuptake 2 storage
Epinephrine comes from?

What does it do?
NE that is converted enzymatically in Adrenal medulla

Travels through blood stream to target organs in SNS system
3 types of andregenic receptors and their subtypes?
Alpha (1, 2)
Beta (1, 2)
Dopaminergic (1-5)
Alpha andregenic receptors types 1 & 2 stimulated by?
1 - epi, NE, Dop

2- Epi, NE
Beta 1 & 2 Andregenic receptors stimulated by?
1- epi, NE dop

2- Epi (only)
Common indication for adregenic agonists? (5 types)?
shock

1) hypovolemic
2) cardiogenic
3) Septic
4) Obstructive
5) Neurogenic
3 examples of indirect stimulation of andregenic receptors?
1) block reuptake
2) inhibir action of COMT & MAO
3) increasing NE transmission
andregenic agonists split into 2 groups? (& characteristics?)
1) catecholamines (no PO, short duration, administered continuously, do not cross blood-brain)

2) Non-catecholamines (opposite)
Nonselective andregenics stimulate all receptors except?
dopamine receptors
(P) EPINEPHRINE
NON-SELECTIVE ADRENERGIC AGONIST

RECEPTOR: A1 A2 B1 B2

PHYSIOLOGICAL AXN(s):
vasoconstrict arteries/veins
vasodil skel muscle
HR up
bronchodilation

THERAPEUTIC USES:
shock (also anaphylactic)
asthma
CPR
glaucoma

ADVERSE FX:
FREQUENT
angina
arrhythmias

CONTRAS:
active labour
closed-angle glaucoma
gen anethesia

*monitor CardioVasc status during*
(P) DOPAMINE
BETA ADRENERGIC AGONIST

RECEPTOR: A1 B1 DOP1/2

PHYSIOLOGICAL AXN(s):
up cardiac output
up BP
up renal perfusion

THERAPEUTIC USES:
hypOtension from shock

ADVERSE FX:
angina
tachycardia
N&V
dyspnea
hypOtension

CONTRAS:
pheocromocytoma
tachyarrhythmias
V fib

*monitor BP**
(P) FENOLDOPAM
DOPAMINERGIC AGONIST

RECEPTOR: a2 DOP1/2

PHYSIOLOGICAL AXN(s):
periph vasodil

THERAPEUTIC USES:
hypertension

ADVERSE FX:
hypOtension
tachycardia

CONTRAS:
sulfite sensitivity

*titrate drug slowly*
*monitor HR & BP*