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4 Cards in this Set
- Front
- Back
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What are the goals of asthma therapy?
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- Control symptoms and prevent exacerbations
- Normalize lung function and decrease airway hyperresponsiveness - Normalize exercise intolerance - Avoid nocturnal symptoms and sleep reduction, minimizing drug side effects |
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What is an inhalation therapy disadvantage?
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Airway obstruction (i.e. mucus plugging) limits delivery
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What therapeutic agents are part of the bronchodilator class?
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- Beta-adrenoceptor agonists
- Methyl xanthines - Anticholinergic drugs |
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What is the mechanism of action of Beta-adrenoceptor agonists?
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Beta2-adrenoceptor activation elevates cAMP, causing relaxation of smooth muscle; the increases in cAMP also inhibits release of inflammatory mediators, but to a
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