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23 Cards in this Set
- Front
- Back
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Sympahtetic NS do to:
a) Heart b) Blood vessels c) eye/sphincters |
a) Increases rate, strength, conduction
b) Alpha 1/2 receptors - constriction, Beta 2 receptors - Dilatation c) Alpha receptors - constriction (mydriasis) Beta receptors - Relaxation |
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Parasympathetic NS:
a) Heart b) Blood vessels c) Eye/sphincter mm d) GI tract e) urinary tract f) Resp tract |
a) Decreases rate, strength, conduction
b) Generally dilates blood vessels c) Miosis/contraction d) Increase motility and secretion e) Contraction of detruser f|) Bronchoconstriction, increased secretions |
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Alpha 1 receptor actions
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Vasoconstriction
Positive iontrope Prostatic smooth muscle contraction |
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Alpha 2 receptor actions
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Vasoconstriciton
Mediate sedation and analgesia in CNS |
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Beta 1 receptor actions
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Increased force of contraction, conduction and rate of impulse formation
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Beta 2 receptor action
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Vascular smooth muscle relaxation
Bronchodilation stabilises mast cells |
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What are teh drugs of the PNS?
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Cholinergic agonists (parasympathomemetics)
Acetylcholinesterase inhibitors muscuranic antagonisits (sympatholytics) |
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What cholinergic agonists is used to tx glaucoma?
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pilocarpine
Contraindicated in uveitis and anterior lens lux |
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What cholinergic agonists is used to induce miosis?
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Carbachol
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What anticholinesterase do we use to a) dx and b) tx myasthenia gravis?
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a) Edrophonium Chloride
b) Neostigmine or pyridostigmine |
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What are anticholinesterase toxicities?
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Salivation
mm tremors Defecation Miosis Collapse |
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What is atropine used for (and what is it)?
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Its a muscarinic antagonist
a) old premed to decrease salivation b) Tx of organophospahte toxicity c) Dilates the pupil e) Increase the heart rate |
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What are the side effects of atropine?
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CNS stimulation (esp in the horse)
Constipation Tachycardia Urinary retention |
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What si the use of tropicamide (and what is it)?
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Its a muscurinic antagonist
Used as a mydratic (drug of choice for ocular exam) |
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What NS system does epinephrine/adrenaline act on?
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Sympathetic NS
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What does adrenaline do/uses of?
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Acts on both alpha and beta receptors
1. Increases HR and force of contraction 2. Induces vasoconstriction Basically used for cardiac arrest and anaphylaxis |
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What is dopamine and what does it induce?
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It is a neurotransmitter
Causes: 1. Vasodilation 2. Increased renal perfusion/filtration (good in ARF) 3.At high doese can induce vasoconstriciton 3. |
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What is dopamine and what does it induce?
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It is a neurotransmitter
Causes: 1. Vasodilation 2. Increased renal perfusion/filtration (good in ARF) 3.At high doese can induce vasoconstriciton 3. |
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What is Phenylpropanolamine used for?
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Urinary incontinence in the bitch
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What is Phenylpropanolamine used for?
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Urinary incontinence in the bitch
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What is Dobutamine and what is its uses?
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Its a B1 selecetive agonist
Uses: In horses to keep a MAP above 70 mmhg In acute cardiac crisis for ionotropic effect |
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What is clenbuterol and what are its uses?
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It is a B2 selective agonist
Uses: Bronchodilation Uterine relaxation Control RAO in horse |
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What is Dobutamine and what is its uses?
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Its a B1 selecetive agonist
Uses: In horses to keep a MAP above 70 mmhg In acute cardiac crisis for ionotropic effect |
