Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
15 Cards in this Set
- Front
- Back
|
What is an example of a strong acid?
|
HCl
|
|
|
What is an example of a strong base?
|
NaOH
|
|
|
A strong acid does what?
|
completely ionizes in water
|
|
|
A weak acid does what?
|
does NOT completely ionize in water
|
|
|
A high Ka means what? A low Ka?
|
High Ka = stronger acid
Low Ka = weak acid |
|
|
A base is what?
|
A proton acceptor
|
|
|
A high Kb means what? A low Kb?
|
High Kb = higher base strength
Low Kb = weak base |
|
|
What is a buffer?
|
A system, usually an aqueous solution, that resists changes in pH upon addition of acid or base.
|
|
|
What is a buffer composed of?
|
Composed of a weak acid and conjugate base or weak base and conjugate acid.
|
|
|
How do you prepare a buffer?
|
Add weak acid and conjugate base together or weak base and conjugate acid together.
|
|
|
How do you form a conjugate base from a weak acid?
|
To form a conjugate base from a weak acid, add a strong base to the weak acid.
|
|
|
How do you form a conjugate acid from weak base?
|
To form a conjugate acid from weak by, add a strong acid to weak base.
|
|
|
Know calculations for Kb and Ka and pH on page 53-55!
|
Know calculations for Kb, Ka, pH and buffer capacity on page 53-55!
|
|
|
What is the definition of buffer capacity?
|
The amount of acid or base to add to 1L of a buffer to change pH by one unit.
The ability of a buffer solution to resist changes in pH upon addition of acid or base. |
|
|
Why do we care about buffer capacity?
|
- Drug stability, buffer formulation where rate constant (k) is the lowest
- Drug solubility, pH can effect solubility. - Drug activity, some drugs aren't active at certain pH - Drug absorption - Patient comfort, can't use certain pH in eyes. |
