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14 Cards in this Set
- Front
- Back
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Barbiturates
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Thiopental, Methohexital
Ultra-short acting |
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Mechanism of barbiturates
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Potentiate effect of GABA
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Side effect of
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Respiratory depression
(also tolerance & dependence) |
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Benzodiazepines
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IV: Midazolam, Lorzepam
Oral: Lorazepam, diazepam,... |
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Use of Benzos
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Anticonvulsant, Anxiolysis, Insomnia, ICU sedation, EtOH withdrawal, Muscular disorders
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Benzos SE
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Tolerance & dependence
paradoxical rxn (rare) |
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Propofol
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Excellent sedative/hypnotic drug (amnesia)
Potentiate GABA (slowing channel closing time) |
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Propofol SE
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Apnea, "Propofol Infusion Syndrome" = acidosis, hypotensive
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Etomidate (Imidazole)
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Short acting IV agent
No analgesic properties Rapid induction Cardiovascularly stable |
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Etomidate SE
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Burns on injection
Adrenal suppression (8hrs) Myoclonic movement |
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Ketamine
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NMDA receptor antagonist
PCP analog - "Dissociative amnesia" Profound analgesic Preserves respiratory effort (bronchodilator, sympathetic stimulant) |
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Ketamine SE
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dyphoria, "bad dreams", hallucination
(causes pupil dilation) |
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Dexmeditomidine
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Centrally acting A-2 agonist
sympatholytic Natural relaxant |
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Dexmeditomidine SE
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Central hemodynamic depression (dose dependent)
Hypotension & bradycardia |
