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31 Cards in this Set

  • Front
  • Back
bind to mitotic spindles of fungi and prevents division
Amphotericin B
bind to sterol on cell membrane
Clotrimazole - Lotrimin
membrane leakage during cell division
Amox. and Clavulinate - Augmentin
A-inhibit bact. pro. cell synthesis
C-beta lactamase inhib.
bind to penicillin binding protein and inhibit bact. pro synthesis in cell wall
Cephalexin - Keflex
binds to penicillin binding pro and inhibit bact. pro synthesis in cell wall
Azithromycin - Zithromax
inhib. pro synthesis by binding to 50s bact. ribosome
inhibit bact. pro. synthesis by interfering with 30S ribosome
bind to 30S and 50S ribosomal subunits and interfere with pro synthesis
competitive antagonist of para-aminobenzoic acid (PABA) which is used by bact. to synthesize folic acid
Sulfamethoxazole with Trimethoprim - Bactrim or Septra
trimethoprim interferes with folic acid at sucessive step giving a synergistic effect
Ciprofloxacin - Cipro
inhibit DNA gyrase (uncoils DNA) and influence nucleic acid metabolism
gene regulation via growth factor receptor activation in the bone marrow
Cyclosporine - Sandimmune
blocks intracellular T cell signalling causing inhib. production of IL-2 by T-cells
Etancercept - Enbrel
inactivates TNF alpha (tumor necrosis factor)
Acyclovir - Zovirax
nucleoside analog (inhib. viral DNA polymerase)
Zidovudine - Retrovir
thymidine analog (chain termination)
Immune Globulins
interfere with virus penetrating cells
? mb one of:
inhib. viral penetration
inhib. viral peptide elongation
degrade viral mRNA
accumulate in food vacuole of parasite and prevents detox of heme metabolism (toxic)
Quinine and Quinidine
inhibit nucleic acid synthesis in parasites
cytotoxic effect on pro and DNA via specific enzyme
Tetrahydrozoline - Visine
Azelastine - Optivar
blocks H1 receptor sites
Ketorolac - Acular
cyclooxygenase inhibitor
Tobramycin - Tobrex
inhib. bacterial pro. synthesis
Timolol - Timoptic
blocks ocular ep - decreasing aqueous humour
Mupirocin - Bactroban
inhibits bact. pro. synthesis
Ketoconazole - Nizarol
inhibits sterol synthesis
Tretinoin - Retin A
decrease hyperkeratinization, increases epidermal thickness and decreases collagen synthesis
Isoretinoin - Accutane
decreases hyperkeratinization, sebaceous gland, sebus and propionibacterium acne (bact.)