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33 Cards in this Set

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Two drugs whose sum effect when given together is equal to the effect from each given separately but at the same time.
Additive
Drug that activates its receptor upon binding.
Agonist
Drug that binds to its receptor without activating it.
Antagonist
Fraction of drug dose that reaches the systemic circulation.
Bioavailability
Drug use that would result in withdrawal symptoms on discontinuation; can be psychological or physiological.
Dependence
Loss of tissue responsiveness that can occur with drug exposure.
Desensitization
All inclusive management of a patient's disease.
Disease management
The route comprising oral, sublingual, nasogastric, or rectal routes of drug absorption.
Enteral route
Elimination of drug that happens after administration but before it reaches the systemic circulation.
First-pass effect
List of drugs stocked by the pharmacy.
Formulary
Time it takes for the drug concentration to fall to 50% in the body
Half-Life
Actions of the body on the drug.
Pharmacokinetics
Dose that is first administered to rapidly achieve a therapeutic concentration.
Loading dose
Doses given to keep a drug at a therapeutic level in the blood.
Maintenance dose
Study of drugs and their action on the body.
Pharmacology
The route comprising routes that bypass the alimentary tract; injectable.
Parenteral route
Actions of the drug on the body.
Pharmacodynamics
Application of drug therapy to disease treatment.
Pharmacotherapy
The effect of two drugs given together when one drug has no effect but increases the response of the other drug, which normally has a lesser effect.
Potentiation
Refers to sites such as albumin where the drug is connected of bound and inactive; influences drug distribution.
Protein binding
Refers to drugs that contain two chemical components that may have different activity.
Racemic
Target for drugs to act on.
Receptor
Extent to which a drug acts on one specific site or receptor.
Selectivity
State reached when input of the drug is equal to the output of drug over the dosing interval.
Steady state
Refers to drug absorption under the tongue.
Sublingual
The result when two drugs are given together and their effect is greater than the effect from each given separately.
Synergism
Having an effect on prenatal development that results in abnormal structure of function.
Teratogenic
Quantitative measure of a drug's safety.
Therapeutic index
Range of drug concentration in the body in which the drug produces the desired response.
Therapeutic range
Study of drugs used to cure, treat, or prevent disease.
Therapeutics
Decrease in susceptibility to a drug's effect from continued use.
Tolerance
Study of drugs as it relates to poisonings and environmental toxins.
Toxicology
Delivered through the skin.
Transdermal