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13 Cards in this Set

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Chloramphenicol
Protein synthesis inhibitor

broad spectrum

blood abnormalities (may appear after therapy has ceased)

infant unable to eliminate ***

***Use other less toxic therapy first
Protein synthesis inhibitor
What is the mech of action for Chloramphenicol?
broad spectrum
What is the spectrum for Chloramphenicol?
blood abnormalities (may appear after therapy has ceased)

infant unable to eliminate ***

***Use other less toxic therapy first
What is the problem with Chloramphenicol?
Chloramphenicol
infant unable to eliminate ***
broad spectrum
What is the spectrum for Sulfonamides?
Sulfonamides
folic acid synthesis inhibitor

broad spectrum

low cost

ease of administration

**kidney damage possible (usually use with lots of water)

resistance common

especially used for otitis media and urinary and vaginal infections
folic acid synthesis inhibitor
What is the mechanism of action for Sulfonamides?
Sulfonamides
used for otitis media and urinary and vaginal infections
low cost
Are sulfonamides low cost or high cost?
used for otitis media and urinary and vaginal infections
What are the main clinical uses of sulfonamides?
Trimethoprim
folic acid synthesis inhibitor

for UTI (urinary tract infection)

Caution folate deficiency
folic acid synthesis inhibitor
What is the mech of action for Trimethoprim?