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20 Cards in this Set
- Front
- Back
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vancomycin
bacitracin |
What are the specific glycopeptides?
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Because it has no beta lactam structure.
Can use in resistant hospital based infections. For colitis |
Why use a glycopeptide?
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Major toxicity limits systemic use except in resistant hospital based infections.
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Why shouldn't you use a glycopeptide?
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Vancomycin
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_________ may be a drug of choice for some types of colitis because it does not absorb well and remains in the intestines.
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Bacitracin
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______ is chiefly a topical agent because of its toxicity.
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Aminoglycosides
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For serious aerobic gram - infections
Broad spectrum Must be used parenterally unless for GI parasites as when treating hepatic coma or prior to bowel surgery (not absorbed orally). Does NOT cross the BBB adequately. Will work intracellularly but has trouble penetrating. Caution: otoxicity and renal damage |
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Aminoglycosides including streptomycin
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For serious aerobic gram - infections
for tuberculosis |
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Broad spectrum
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What is the spectrum of Aminoglycosides?
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Protein synthesis inhibitors
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What is the mech of action for Aminoglycosides?
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Aminoglycosides
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Streptomycin is part of the this group?
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otoxicity and renal damage
hearing loss (may be irreversible) |
What are the side effects of Aminoglycosides?
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DNA inhibitors or prevent bacterial DNA from replicating.
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What is the mech of action for Quinolones/Floroquinolones?
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broad spectrum
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What is the spectrum for Quinolones/Floroquinolones?
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*** Cartilage and tendon erosion in young dogs and rats explains contraindications in pregnant or nursing women or in children under 18.
nausea anaphylaxid rashes visual disturbances phototoxicity depressed bone marrow acute interstitial nephritis arthritis tendonitis |
What are the adverse effects of taking Quinolones/Floroquinolones?
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adverse effects of taking Quinolones/Floroquinolones
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*** Cartilage and tendon erosion in young dogs and rats explains contraindications in pregnant or nursing women or in children under 18.
nausea anaphylaxid rashes visual disturbances phototoxicity depressed bone marrow acute interstitial nephritis arthritis tendonitis What drug? |
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Macrolides including erythromycin
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inhibits protein synthesis
spectrum sim. to penicillin (narrow spectrum) resistant strain develop easily allergic reactions may occur and GI side effects are common. Otherwise low toxicity |
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Macrolides including erythromycin
Lincosamides |
Protein synthesis inhibitor
Use this when patients are allergic to pencillin. |
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Tetracycline
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decrease the effectiveness of oral contraceptives
broad spectrum Not a fungi, but may permanently discolor children's teeth if used from fourth month of fetal life though eight year of childhood. Photosensitivity (use sunscreen) Superinfection a problem with chronic therapy (acne). need food in stomach but not milk or antacids. |
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Not a fungi, but may permanently discolor children's teeth if used from fourth month of fetal life though eight year of childhood.
Photosensitivity (use sunscreen) Superinfection a problem with chronic therapy (acne). |
What are the side effects of tetracycline?
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Lincosamides
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specifically for anaerobic bacteria
causes colitis can be used if allergic to penicillin if other less toxic alternatives don't work. |
