Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
13 Cards in this Set
- Front
- Back
|
Normal function of the synapse.
|
1. stimulation of neuron #B or effector organ.
2. Removal of the stimulation of neuron #B or effector. Depending on transmitter substance, stimulation may be stopped by the: a. use of an enzyme to destroy the transmitter (Acetylcholine destroyed by cholinesterase-important) b. reuptake of the transmitter into neuron #A (Norepinephrine - most important removal mechanism) (much less significant for ACE) |
|
|
1. stimulation of neuron #B or effector organ.
2. Removal of the stimulation of neuron #B or effector. |
What is the normal function of the synapse?
|
|
|
it depends on what neurotransmitter it is.
|
What does the removal of the stimulation of neuron #B or effector depend on?
|
|
|
a. use of an enzyme to destroy the transmitter
b. reuptake of the transmitter into neuron #A |
Depending on transmitter substance at the synapse, how can the stimulation be stopped?
|
|
|
cholinesterase
|
What enzyme destroys the neurotransmitter, Acetylcholine?
|
|
|
reuptake of the transmitter into neuron A.
|
What process is the most important removal mechanism for NE at the synapse?
|
|
|
effector
stimulation stopped enzyme cholinesterase reuptake Norepinephrine |
1. stimulation of neuron #B or _________ organ.
2. Removal of the __________ of neuron #B or effector. Depending on transmitter substance, stimulation may be _________ by the: a. use of an ________ to destroy the transmitter (Acetylcholine destroyed by ____________ -important) b. ________ of the transmitter into neuron #A (____________- most important removal mechanism) (much less significant for ACE) |
|
|
a. receptor agonist acts a transmitter themselves by combining with the receptor.
b. stimulate the release of the 1st neuron's transmitter substance. c. inhibit or block the removal of the body's natural transmitter substance (cholinesterase inhibitors) |
How does the receptor AGONIST
(the drug which stimulates) alter normal synapse function? |
|
|
agonist
stimulate removal |
a. receptor _______ acts a transmitter themselves by combining with the receptor.
b. _________ the release of the 1st neuron's transmitter substance. c. inhibit or block the ________ of the body's natural transmitter substance (cholinesterase inhibitors) |
|
|
Receptor antagonist blocks receptor sites so they can't be stimulated.
This in turn, blocks the release of body's own transmitter substance. |
How does the receptor ANTAGONIST
(the drug which inhibits) alter normal synapse function? |
|
|
antagonist
transmitter |
Receptor __________ blocks receptor sites so they can't be stimulated.
This in turn, blocks the release of body's own __________ substance. |
|
|
Cholinergic
|
__________ receptors (Muscarinic and Nicotinic) respond to Acetylcholine.
|
|
|
Adenergic
|
__________ receptors (alpha, b1, b2) respond to Norepinephrine.
|
