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14 Cards in this Set

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a. true
A patient's ability to respond to a given concentration of drug at the active site may actually be altered by a simple factor like the time of day.

a. true
b. false
b. decreased.
Aged individuals usually require a different drug dosage than young adults. Changes in their hepatic and renal systems often require that the dosage be _________ to maintain proper therapeutic levels.

a. increased
b. decreased.
a. adverse responses specific to a drug
Well trained medical personnel should always be able to anticipate and minimize or completely prevent:

a. adverse responses specific to a drug
b. drug allergies
c. drug idiosyncracies
c. more rapidly metabolized
If drug A increases the microsomal enzyme system in the liver, it can cause another drug, B, to be:

a. more rapidly absorbed
b. less rapidly absorbed
c. more rapidly metabolized
d. less rapidly metabolized
e. both B and D of the above
a. high pH
Acidic drugs are MORE likely to be ionized when their environment is at a ____________.

a. high pH
b. low pH
d. all of the above
Binding of some drugs to plasma proteins has an effect on:

a. onset time
b. duration of action
c. distribution of the drug
d. all of the above
e. only a and c of the above
e. only b and c of the above
Special cautions must be taken with ___________ when administrating drugs because hepatic and renal systems are often not operating at full capacity.

a. overweight individuals
b. infants
c. aged individuals
d. all of the above
e. only b and c of the above
c. synergistic
The greatest effect is expected when two drugs given together have _________ effects.

a. additive
b. antagonistic
c. synergistic
c. a macromolecule in cell or tissues with which a drug interacts to produce a characteristic biological response.
A receptor is:

a. a compound which INCREASES or intensifies the activity of a cell.

b. a compound which DECREASES or prevents and activity of a cell.

c. a macromolecule in cell or tissues with which a drug interacts to produce a characteristic biological response.
a. competitive
Which type of antagonist has effects that are reversible, especially in the presence of more agonists:

a. competitive
b. noncompetitive
b. are not
An antacid is an example of a drug whose effect ___________ mediated by a receptor.

a. are
b. are not
b. is not
A drug is more likely to pass through cell membranes if it _____________ highly ionized.

a. is
b. is not
b. intestine than the stomach
A drug that is a weak acid is more likely to be ionized in the:

a. stomach than the intestine
b. intestine than the stomach
b. distribution
The main factor that influences whether a particular drug has an effect on the brain is the drug's:

a. absorption
b. distribution
c. metabolism
d. excretion