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27 Cards in this Set
- Front
- Back
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Name a NNRTI-based regimen
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Efavirenz
Lamivudine Tenofovir |
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Name a PI-based regimen
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Kaletra(Lopinavir/Ritonavir)
Lamivudine Zidovudine |
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Name an NRTI-based regimen
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Abacavir
Didanosine Stavudine |
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What 2 drugs are in Combivir
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NRTI combination:
Zidovudine Lamivudine |
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Food decreases levels of these drugs
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DDI- 55%
Indinavir- 77% Efavirenz |
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Which PIs should you take with food?
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Atazanavir- > bioavailability
Kaletra- > AUC 48-80% Nelfinavir- > levels 2-3 fold |
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what is the empiric Tx for CAP? (Non-hosp)
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Non-hospitalized patients:
Healthy no AB: Macrolide With recent AB: FQ Comorbidity: FQ Aspiration: Augmentin |
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what is the empiric Tx for CAP? (Hosp)
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FQ
With severe pneumonia: Pipercillin/Tazobactam |
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Which drug inhibits formation of tetrahydrofolic acid?
Inhibits dihydrofolate reductase? |
Trimethoprim
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Name the Beta-lactamase inhibitors
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Augmentin- Amox/Clauv Acid
Unasyn- Amp/sulbactam |
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PCN that you should avoid with hepatic failure
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Nafcillin
Also causes bone marrow suppression |
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The only CONDM drug that does not require dose reduction with renal pts
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Methecillin
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These drugs increase Na load and can cause hypokalemia
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Carbecillin
Ticarcillin |
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Anti-pseudomonal PCN Tx
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Pipercillin with Tobramycin for double coverage
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what is the dose for Gentamycin
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Use actual body weight:
5mg/kg |
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What is the trough for Gentamycin?
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2
If trough is high, hold dose and increase interval: ex Q8 to Q16 |
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If pt is on dialysis with CrCl <30, what do you do
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Get peak and trough after 3rd dose; decrease interval if trough is low
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Name some side effects of Tetracycline
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Hepatotoxicity
Phototoxicity |
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Name the twice a day NRTI combo drugs
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Combivir-Zidovudine/Lamivudin
Trizivir-Zido/Lami/Ziagen |
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Name the once a day NRTI Combo drugs
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Epzicom-Epivir/Ziagen
Truvada-Emtriva/Viread |
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What is the DOC for asthma prophylaxis and blocks the late reaction?
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Inhaled corticosteroids
Ex: QVAR |
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Drug for allergy-related asthma
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Xolair: monoclonal antibody
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Asthma drug beneficial for night symptoms but with many side effects
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Theophyline
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How do you treat enterococcus?
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Pipercillin/Tazobactam
Carbapenems Imipenems |
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how do you treat a resistant E.Coli?
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Cephalosporins
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Why is Rifampin added to Vanco for Tx of endocarditis?
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For synergy
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Tx for ESBLs
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FQ
Pipercillin/Tazobactam |
