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27 Cards in this Set

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Name a NNRTI-based regimen
Efavirenz
Lamivudine
Tenofovir
Name a PI-based regimen
Kaletra(Lopinavir/Ritonavir)
Lamivudine
Zidovudine
Name an NRTI-based regimen
Abacavir
Didanosine
Stavudine
What 2 drugs are in Combivir
NRTI combination:

Zidovudine
Lamivudine
Food decreases levels of these drugs
DDI- 55%
Indinavir- 77%
Efavirenz
Which PIs should you take with food?
Atazanavir- > bioavailability
Kaletra- > AUC 48-80%
Nelfinavir- > levels 2-3 fold
what is the empiric Tx for CAP? (Non-hosp)
Non-hospitalized patients:

Healthy no AB: Macrolide
With recent AB: FQ
Comorbidity: FQ
Aspiration: Augmentin
what is the empiric Tx for CAP? (Hosp)
FQ

With severe pneumonia: Pipercillin/Tazobactam
Which drug inhibits formation of tetrahydrofolic acid?
Inhibits dihydrofolate reductase?
Trimethoprim
Name the Beta-lactamase inhibitors
Augmentin- Amox/Clauv Acid
Unasyn- Amp/sulbactam
PCN that you should avoid with hepatic failure
Nafcillin

Also causes bone marrow suppression
The only CONDM drug that does not require dose reduction with renal pts
Methecillin
These drugs increase Na load and can cause hypokalemia
Carbecillin
Ticarcillin
Anti-pseudomonal PCN Tx
Pipercillin with Tobramycin for double coverage
what is the dose for Gentamycin
Use actual body weight:

5mg/kg
What is the trough for Gentamycin?
2

If trough is high, hold dose and increase interval: ex Q8 to Q16
If pt is on dialysis with CrCl <30, what do you do
Get peak and trough after 3rd dose; decrease interval if trough is low
Name some side effects of Tetracycline
Hepatotoxicity
Phototoxicity
Name the twice a day NRTI combo drugs
Combivir-Zidovudine/Lamivudin
Trizivir-Zido/Lami/Ziagen
Name the once a day NRTI Combo drugs
Epzicom-Epivir/Ziagen
Truvada-Emtriva/Viread
What is the DOC for asthma prophylaxis and blocks the late reaction?
Inhaled corticosteroids

Ex: QVAR
Drug for allergy-related asthma
Xolair: monoclonal antibody
Asthma drug beneficial for night symptoms but with many side effects
Theophyline
How do you treat enterococcus?
Pipercillin/Tazobactam
Carbapenems
Imipenems
how do you treat a resistant E.Coli?
Cephalosporins
Why is Rifampin added to Vanco for Tx of endocarditis?
For synergy
Tx for ESBLs
FQ
Pipercillin/Tazobactam