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27 Cards in this Set
- Front
- Back
Name a NNRTI-based regimen
|
Efavirenz
Lamivudine Tenofovir |
|
Name a PI-based regimen
|
Kaletra(Lopinavir/Ritonavir)
Lamivudine Zidovudine |
|
Name an NRTI-based regimen
|
Abacavir
Didanosine Stavudine |
|
What 2 drugs are in Combivir
|
NRTI combination:
Zidovudine Lamivudine |
|
Food decreases levels of these drugs
|
DDI- 55%
Indinavir- 77% Efavirenz |
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Which PIs should you take with food?
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Atazanavir- > bioavailability
Kaletra- > AUC 48-80% Nelfinavir- > levels 2-3 fold |
|
what is the empiric Tx for CAP? (Non-hosp)
|
Non-hospitalized patients:
Healthy no AB: Macrolide With recent AB: FQ Comorbidity: FQ Aspiration: Augmentin |
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what is the empiric Tx for CAP? (Hosp)
|
FQ
With severe pneumonia: Pipercillin/Tazobactam |
|
Which drug inhibits formation of tetrahydrofolic acid?
Inhibits dihydrofolate reductase? |
Trimethoprim
|
|
Name the Beta-lactamase inhibitors
|
Augmentin- Amox/Clauv Acid
Unasyn- Amp/sulbactam |
|
PCN that you should avoid with hepatic failure
|
Nafcillin
Also causes bone marrow suppression |
|
The only CONDM drug that does not require dose reduction with renal pts
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Methecillin
|
|
These drugs increase Na load and can cause hypokalemia
|
Carbecillin
Ticarcillin |
|
Anti-pseudomonal PCN Tx
|
Pipercillin with Tobramycin for double coverage
|
|
what is the dose for Gentamycin
|
Use actual body weight:
5mg/kg |
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What is the trough for Gentamycin?
|
2
If trough is high, hold dose and increase interval: ex Q8 to Q16 |
|
If pt is on dialysis with CrCl <30, what do you do
|
Get peak and trough after 3rd dose; decrease interval if trough is low
|
|
Name some side effects of Tetracycline
|
Hepatotoxicity
Phototoxicity |
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Name the twice a day NRTI combo drugs
|
Combivir-Zidovudine/Lamivudin
Trizivir-Zido/Lami/Ziagen |
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Name the once a day NRTI Combo drugs
|
Epzicom-Epivir/Ziagen
Truvada-Emtriva/Viread |
|
What is the DOC for asthma prophylaxis and blocks the late reaction?
|
Inhaled corticosteroids
Ex: QVAR |
|
Drug for allergy-related asthma
|
Xolair: monoclonal antibody
|
|
Asthma drug beneficial for night symptoms but with many side effects
|
Theophyline
|
|
How do you treat enterococcus?
|
Pipercillin/Tazobactam
Carbapenems Imipenems |
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how do you treat a resistant E.Coli?
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Cephalosporins
|
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Why is Rifampin added to Vanco for Tx of endocarditis?
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For synergy
|
|
Tx for ESBLs
|
FQ
Pipercillin/Tazobactam |