Pharm Test Iii

Front 1

common skin diseases

Back 1

dermatitis, eczema, acne, urticaria, psoriasis, viral warts, skin cancer, fungal infxn

Front 2

vehicles of derm meds

Back 2

baths, lotions, gels, powders, pastes, creams, oinments

Front 3

choice of vehicle depends on

Back 3

solubility of drug; ability to hydrate stratum conreum; stability of drug vehicle, ability to retard evaporation from the skin

Front 4

baths are ________ soluble, _______solutions that sooth the ___________.

Back 4

completley water soluble; colloidal; skin

Front 5

the ________ pressure of these preparations is high, so it draws _________ from the tissue.

Back 5

oncotic; water;

Front 6

they are good for swollen tissue to reduce _________

Back 6

swelling

Front 7

baths do not achieve good _______ absorption

Back 7

systemic

Front 8

Lotions are mostly _______, they ________ giving skin a cooling action, which causes __________ that decreases inflammaiton

Back 8

water; evaporate; vasoconstriction

Front 9

lotions do not _______ the stratum corneum adn are not good for _________ absorption

Back 9

hydrate; systemic

Front 10

gels are semi-solid _____ solns and ______. They contain ______. They enhance absorption through the ______

Back 10

colloidal; suspensions; alcohol; skin

Front 11

gels are a cros btwn a _____ and a tincture

Back 11

bath

Front 12

powders are used to _____ an area esp a weepy wound. They absorb _______.

Back 12

dry; water

Front 13

powders cause _____ that can prevent ________

Back 13

crusting; infxn

Front 14

care must be taken to avoid ________ of small particles of powder

Back 14

aspiration

Front 15

caution should be used when using _________ as it can cause a __________ infxn

Back 15

corn starch; yeast

Front 16

pastes are thick _______ that contains _______. They are very _______.

Back 16

ointments; poweder; adhesive

Front 17

They are ideally used when ______ is wanted, as no extra ________ is wanted

Back 17

adherency; dressing

Front 18

the two types of creams are _______ and __________

Back 18

oil in water and water in oil

Front 19

Oil in water mixes with ______ discharges and is ______, which is good when daily debridment is needed

Back 19

serous; washable

Front 20

water in oil is a good vehicle for _____ soluble substances. It is used when you want _______ drug to cross the ______ into _______ circulation.

Back 20

fat; active; skin; systemic

Front 21

ointments are ______ soluble and improve ________ of drugs because it ______ the skin an example is _______

Back 21

water; penetration; hydrates; polyethylene glycol (PEG)

Front 22

ointments that are ________ agents, mix with water and ________, allowing active drug to get ______ the exudate

Back 22

emulsifying; exudates; below

Front 23

non-emulsifying ointments work as ________ dressing and enhance __________. water will not mix or ______, which increases ______ of the skin, which is important when trying to get across the _________

Back 23

occlusive; hydration; escape; hydration; skin

Front 24

causes of eczema and dermatitis are

Back 24

irritants and allergens; infxns (may be a sign of systemic illness); drugs (allergic rxn); environmental factors (toxins); local factors (venous stasis)

Front 25

eczema and dermatitis txs include _________ which reduces skin water loss, ________ that decrease inflammation, and ________ for secondary infections

Back 25

ointments; glucocorticoids; antibiotics

Front 26

__________ is a cream that inhibits inflammatory cytokine release (antiinflammatory)

Back 26

elidel cream

Front 27

it has minimal systemic _______

Back 27

immunosuppression

Front 28

its indicated for _______ dermatitis and _______ dermatitis, and is an alternative to __________

Back 28

atopic; contact; corticosteroids

Front 29

________ is the most common dermatologic problem we will treat in family practice

Back 29

acne

Front 30

acne presents in

Back 30

comedones; papules; pustules; nodules; cysts; scars

Front 31

organisms responsible for acne are

Back 31

propionibacterium acnes; staph

Front 32

systemic ______ and OCP can cause acne secondary to _______ stimulation of ________glands

Back 32

cS; androgenic; sebaceous

Front 33

acne tx include what classes

Back 33

keratolytics and antibacterial

Front 34

examples of keratolytics which ____ up keratin ____ are

Back 34

dry; plugs; benzoyl peroxide, selenium sulfide

Front 35

strengths of benzoyl peroxide are ___, ____, _____ percent and are available _____

Back 35

5; 10; 15; otc

Front 36

The keratolytics that are available only by perscription

Back 36

Tretinoin (retin -A) and Isotretinoin (accutane)

Front 37

these meds are all

Back 37

retinoic acid derivatives that decreases the size of keratin plugs and prevents them

Front 38

Retin-A is a ______ preparation, in the form of ____ and _____

Back 38

topical; cream; gel

Front 39

accutane is administered

Back 39

po

Front 40

accutane is on a ________ disribution system. It is a _______ drug, so care must be taken to prevent ________

Back 40

restricted; teratogenic; pregnancy

Front 41

accuate is good for ________ distribution of acne, but has ________ and ________side effects

Back 41

wide; gi; psychiatric (? increased suicide)

Front 42

antibiotics treatments are administered

Back 42

topically and orally

Front 43

Topical ance abtx include _____, ________, and ______ which are the ________ of acne tx

Back 43

ees; clindamycin; azelaic acid (Azelec, Finacea); mainstay

Front 44

oral abtx is used mostly with ________ acne and is used at a lower ______ than when tx an URI

Back 44

cystic; dose

Front 45

examples of oral acne tx are

Back 45

tetracycline (doxycycline) and ees

Front 46

use of systemic abtx increase the chance for ______ infxn. If using systemic abtx use antibiotic from a _______ _______ to tx an URI

Back 46

superinfxn, different class.

Front 47

_________ and _________ are used in the tx of rosacea and are use ________ only

Back 47

Azelaic acid; metronidazole; topically

Front 48

psoriasis is a ________ disorder that causes ________ skin plaques with __________ infiltrates in the dermis, which is believed to be caused by an _________ response

Back 48

hyperproliferative; thickened; inflammatory; immune

Front 49

psoriasis tx is ______ and ______

Back 49

topical and systemic

Front 50

topical tx of psoriasis are

Back 50

keratolytics (benzoyl peroxide/sillium sulfate); coal tar; CS

Front 51

systemic tx of psoriasis are

Back 51

CS (tx infiltrates in the dermis); methotrexate (chemo agent prevents skin cell division); hydroxyurea (chemo); cyclosporin (antirejection med; leaves vulnerable to opportunisitic dz) (need prophylaxis for CMV) infliximab (Remicade) (see an increase in malignancy)

Front 52

classification of glucocorticosteroids are

Back 52

mild; moderate; potent; very potent

Front 53

only ____ is used on the face

Back 53

mild

Front 54

examples of glucocorticoids are

Back 54

hydrocortisone; (eczema); triamcinolone (lotion, cream, ointment, (moderate)); desonide (potent); Mometasone (very potent)

Front 55

sunscreens filter _____ and ____ and are classified as

Back 55

UVA; UVB; mild (<10); moderate (10-15); strong (>15)

Front 56

________ is the only sunscreen that is completely obstructive

Back 56

zinc

Front 57

systemic tx for psoriasis include

Back 57

corticosteroids; methotrexate; hydoxyurea; clycosporin; infliximab (Remicade)

Front 58

CS tx ________ in dermis; methotrexate is a ___ drug that prevents ______ of skin cells

Back 58

infiltrates; chemo; divsion

Front 59

cycloporin is a _______ drug that decreases infiltration of _______ cells. One must be cautions as this make one suseptable to ______ dz

Back 59

immunosuppresant; inflammatory; opportunistic

Front 60

Infliximab (Remicade)is a _______ anitbody that is given via ___. Another med of this type is ______ which can be given at ________

Back 60

moniclodal; IV; Enbrel; home

Front 61

levels of CS are

Back 61

mild; moderate; potent; very potent

Front 62

Use only ____ CS on the face

Back 62

mild

Front 63

examples of CS are

Back 63

hydrocortisone (mild); triamcinolone (moderate); desonide (potent); mometasone (very potent)

Front 64

chilren never get more than ____ CS

Back 64

moderate

Front 65

sunscreens: mild ____; moderate _____; strong _____; ____ is completely obstructive

Back 65

<10; 10-15; >15; zinc

Front 66

Tx of lice is _________. for hair infestation, apply and leave for _____ minutes repeat in _______, use a ___ ____ _____ to remove nits

Back 66

permethrin (Nix, RID); 10; one week; fine tooth comb

Front 67

Tx of scabies is ______. Apply to skinadn leave for ____-____ hours; repeat in ____

Back 67

permethrin (Elimite); 8-14 hours; 14 days

Front 68

side effects of antiparasitic tx are:

Back 68

edema; stinging; erythema; rash

Front 69

Tx for hair loss include

Back 69

Minoxidil (Rogaine); Finestaride (Propecia)

Front 70

Rogaine is a __________, who's effects are not ______ or _______; Finestaride is a __________

Back 70

vasodilator; predictable; permanent; dihydrotestosterone inhibitor

Front 71

topical tx for fungal skin infections include

Back 71

clotrimazole (mycelex); miconazole (monistat); terbinafine (Lamisil); ketoconazole (nizoral); tolnalfate (Tinactin); nystatin (mycostatin)

Front 72

_______ and _________ are the oldest tx

Back 72

clotrimazole; miconazole

Front 73

Terbinafine (Lamisil) route of admin is

Back 73

po

Front 74

ketoconazole is avaialbe as a

Back 74

lotion; cream; shampoo

Front 75

tolnaftate (Tinactin) is used to moslty tx

Back 75

athletes foot

Front 76

nystatin (mycostatin) good to tx

Back 76

yeast associated with diaper rash

Front 77

systemic fungal tx include

Back 77

ketoconazole (nizoral); itraconazole (sporanox)' terinafine (lamisil); griseofulvin(Grisactin)

Front 78

ketoconazole (nizoral) is administered via

Back 78

injection; po

Front 79

itraconazole is avialbe via

Back 79

po

Front 80

Lamisil is the only one safe to tx _________ and is less _______ than griseofulvin

Back 80

onchomhycosis; hepatotoxic

Front 81

Grisefulvin is very

Back 81

hepatotoxic