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15 Cards in this Set

  • Front
  • Back
causes of angina
inadequate blood flow to heart muscle
accumulation of metabolites (lactic acid)
ischemic heart dz (plaque/vasospasm)
goal of therapy
increase blood supply
decrease work on heart
arterial blood pressure determines systolic _______ stress
wall
________ tone determines diastolic wall stress
venous
ways of regulating vascular tone
increase cGMP
decrease intracellular Ca
meds used to tx AP
nitrates/nitrites
CCB
BB
examples of nitrates/nitrites
nitroglycerin
nitroprusside
isosorbide dinitrate and montitrate
routes and dosing of nitro
SL tabs/spray 0.3, 0.4, 0.6mg)
oral capsules (chronic tx)
ointments
patches
IV soln
isosorbide dosing
immediate release and sustained release tablets
nitrate SE
hypotension (esp elderly), HA

tolerance (use asymmetric schedule)

coronary steal
CCB meds used to tx CHF
verapamil
diltiazem
dihydropyridines are used only with _________ angina
vasospastic
SE of CCB/dihydropyridines
decreased CO, - inotropic effect, hypotension, peripheral edema
BB
lower myocardial oxygen needs
tx options
angina of effort

vasospastic angina
ustable angina
nitrate
CCB, nitrate