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19 Cards in this Set
- Front
- Back
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Sulfamethoxazole/ trimethaprim ( sulfonamides) |
Sulfamethoxazole/trimethoprim MECHANISM OF ACTION:Inhibit the growth of bacteria ADVERSE EFFECTS:Allergic reaction, diarrhea, rashes INDICATIONS: Against gram negative and gram positive organisms.Urinary tract infections, respiratory tract infections CONTRAINDICATIONS:Drug Allergy |
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Penicillin ( antibiotic) |
Amoxicillin, ampicillin, penicillin G andpenicillin V potassium MECHANISM OF ACTION:Inhibition of the bacterial cell wall synthesis ADVERSE EFFECTS:Urticaria, pruritus, angioedema INDICATIONS:Gram positive bacteria (streptococcus,enterococcus, staphylococcus) CONTRAINDICATIONS:Drug Allergy |
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Cephalosporin ( antibiotic) |
1rst Generation: cefazolin 2nd: cefoxitin 3rd:Ceftazidime MECHANISM OF ACTION: (Bactericidal)interferes with bacterial cell wall synthesis ADVERSE EFFECTS:Rash, urticaria INDICATIONS: Gram positive, gram negative and anaerobic bacteria CONTRAINDICATIONS: drug allergy |
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Tetracycline ( antibiotic) |
MECHANISM OF ACTION:( Bacteriostatic) inhibit protein synthesis ADVERSE EFFECTS:Discoloration of permanent teeth in fetus and children INDICATIONS: Chlamydia, Mycoplasma, Rickettsia CONTRAINDICATIONS:Drug allergy, pregnancy |
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Gentamicin ( aminoglycosides) |
( antiobiodics) MECHANISM OF ACTION:Prevent protein synthesis in bacteria ADVERSE EFFECTS:Nephrotoxicity, ototoxicity INDICATIONS: Gram - infections and specific conditions with gram + cocci CONTRAINDICATIONS:Drug allergy |
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Ciprofloxacin ( quinolones) |
Antibiotics MECHANISM OF ACTION:Destroy bacteria by altering the DNA ADVERSE EFFECTS:Headache, dizziness, increased liver levels,Rash, urticaria INDICATIONS:Gram - and selected gram + CONTRAINDICATIONS:Drug Allergy |
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Acyclovir ( antiviral) |
MECHANISM OF ACTION:Blocking the activity of a polymerase enzyme that normally stimulates the synthesis of new viral genomes. ADVERSE EFFECTS:Nausea, diarrhea, headache, burning when applied topically INDICATIONS:Herpes, Hepatitis, Varicella CONTRAINDICATIONS:Drug allergy |
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Protease inhibitor: indinavir ( antiretroviral)
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MECHANISM OF ACTION:inhibit the protease retroviral enzyme. ADVERSE EFFECTS:Bone marrow suppression, nausea, headache,weakness INDICATIONS:HIV Infection CONTRAINDICATIONS:Drug allergy
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Reverse Transcriptase Inhibitors: Zidovudine ( antiretroviral) |
MECHANISM OF ACTION:block activity of the enzyme reverse transcriptase. ADVERSE EFFECTS:Bone marrow suppression, nausea, headache, weakness INDICATIONS:HIV Infection CONTRAINDICATIONS:Drug allergy
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Isoniazid (INH) ( antitubercular) |
Mechanism of Action:Inhibit protein synthesis, inhibiting cell wall synthesis Adverse Effects:Liver toxicity Indications:Tuberculosis Contraindications: drug allergy, renal or liver dysfunction |
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Flucanazole/ Amphotericin B ( antifungal) |
MECHANISM OF ACTION:Binding to sterols in the cell membranes of the fungi which results with death to the cell ADVERSE EFFECTS: hepatotoxicity INDICATIONS: Fungal infections CONTRAINDICATIONS:Drug allergy, liver failure, kidney failure |
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NSAIDS: Ibuprofen, Aspirin, Celecoxib- COX 2 |
MECHANISM OF ACTION:Relieve pain, headache, and inflammation by blocking the chemical activity of the enzyme called cyclooxygenase (COX). ADVERSE EFFECTS: Gastrointestinal problems: heartburn, nausea,vomiting and gastrointestinal bleeding INDICATIONS:Pain, fever and inflammation CONTRAINDICATIONS: Drug allergy, patients at risk for bleeding |
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Allopurinol |
MECHANISM OF ACTION:Inhibition of the enzyme xanthine oxidase,prevents uric acid production ADVERSE EFFECTS:Aplastic anemia INDICATIONS: gout CONTRAINDICATIONS:Drug allergy |
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Cytarabine, Methotrexate |
MECHANISM OF ACTION:Cell-cycle specific analogues that work by antagonizing the actions of key cellular metabolites. ADVERSE EFFECTS:Hair loss, nausea and vomiting, diarrhea and myelosuppression INDICATIONS:Solid tumors and hematologic cancers CONTRAINDICATIONS: drug allergy, and immunosuppression patients |
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Cyclophosphamide, Mechlorethamine
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MECHANISM OF ACTION: Prevent cancer cells from reproducing ADVERSE EFFECTS:Hemorrhagic cystitis INDICATIONS:Malignancies (solid & hematologic tumors) CONTRAINDICATIONS:Drug allergy |
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Doxorubicin
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MECHANISM OF ACTION:Blocks DNA synthesis ADVERSE EFFECTS:Hair loss, nausea & vomiting, myelosuppression
INDICATIONS:Solid tumors and hematologic malignancies CONTRAINDICATIONS:Drug allergy |
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Cyclosporine |
MECHANISM OF ACTION:Suppress certain T-lymphocyte cell lines. ADVERSE EFFECTS:Hypertension, tremors, INDICATIONS:Prevention of organ rejection CONTRAINDICATIONS:Drug allergy, hepatic or renal failure,hypertension |
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Diptheria & tetnus toxoids, acellular pertussis vaccine, hepatitis B immunoglobulin, influenza, varicella virus vaccine |
MECHANISM OF ACTION:Vaccine and toxoids that are given intramuscularly to work by stimulating the humoral immune system ADVERSE EFFECT:Fever, rash, soreness at injection site, urticarial,convulsions, dyspnea INDICATIONS:Prevention of illness CONTRAINDICATIONS:Drug allergy, eggs or yeast allergy |
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Two Examples of synergistic drugs |
1) penicillin & genatmicin 2) B6 & isoniazid ( INH) |
