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3 Cards in this Set

  • Front
  • Back

Glucocorticoid

-affects intermediate carb metabolism


-major present in body: cortisol (hydrocortisone)


-w/out stress body produces 20mg daily


-MOA: binds to specific receptor & forms a steroid-receptor complex


-⬇️ growth, ⬇️ glucose use, ⬆️ gluconegenesis, membrane function, enzyme action, anti-inflammation, carb metabolism


-not curative, palative for symptoms mine

Mineralocorticoids

-affects water & electrolyte composition in body


-MOA: binds to specific receptor & forms a steroid-receptor complex


-effects: has lag time


-⬆️ sodium retention, ⬆️ potassium loss, edema & hypertension adverse

Adverse reactions

-metabolic: moon face, truncal obesity, buffalo hump


-infection


-peptic ulcer


-CNS: personality changes, depressed, euphoria


-⬆️ ophthalmic pressure


-adrenal crisis


-oral: slow healing, candidiasis