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30 Cards in this Set
- Front
- Back
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gastric acid disease include what 2 things
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peptic ulcers
gastroesophageal reflux disease (GERD) |
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what are the 3 types of drugs that reduce gastric acid
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anatcids
H2 receptor antagonists proton pump inhibitors |
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what is the 1 antacid we're supposed to know
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magnesium hydroxide plus aluminum hydroxide
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what are the 4 H2-Receptor Antagonists drugs
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Cimetidine
Rantidine Famotidine Nizatidine |
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what is the most commonly prescribed drugs worldwide
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H2-Receptor Antagonists
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H2 receptor blockers are gradually being supplanted by what type of drugs?
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proton pump inhibitors
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what have become the drugs of choice in the treatment of acid-peptic disorders
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proton pump inhibitors
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what provides ulcer healing in the majority of patients with uncomplicated disease
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night time suppression of gastric acid
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which provides more effective ulcer healing and faster relief: proton pump inhibitors or H2 receptor antagonists
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proton pump inhibitors
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proton pump inhibitors heal more than what % of duodenal ulcers within a month
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90%
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50% of patients with GERD exhibit what
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erosion of the esophagus
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what are the 3 commonly used proton pump inhibitors
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Esomeprazole
Omeprazole Lansoprazole |
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a majority of peptic ulcers are directly related to what 2 things
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H pylori infections
nonsteroidal anti-inflammatory drugs (NSAIDs) |
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whats the most effective therapy for H pylori infections
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combination of 2 antibiotics and a proton pump inhibitor
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what are the 2 antibiotics given for H pylori
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clarithromycin
amoxicillin |
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what drug can be substituted for amoxicillin in those patients who may be allergic to the penicillins
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metronidazole
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ulcers caused by aspirin or other NSAIDs can be effectively treated with what
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H2 antagonists or proton pump inhibitors
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what is the common prokinetic drug
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metoclopramide
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drug induced GI motility increase is mediated through stimulation of what receptors
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muscarinic
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Metoclopramide
MOA type |
blocks dopamine D2 receptors in the chemoreceptor trigger zone of the medulla
potent antiemetic drug |
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what are the 3 antiemetic drugs
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ondansetron
prochlorperazine dronabinol |
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what are the most popular durgs of the antidiarrheal agents
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opioid agonists
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what are the 2 opioid agonists
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loperamide (imodium)
diphenoxylate |
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Metoclopramide
- what kind of drug is it - what is it given for? - what does it do? |
- prokinetic drug
- reflux disease - inhibit motility - increase motility and decrease reflux bad if it gets into blood |
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Odansetron
- what kind of drug is it - what does it effect |
- Antiemetic drug
- effects seratonin mechanisms in the brain - very effective in cancer chemo |
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Prochlorperazine
- what kind of drug is it - what does it do |
- Antiemetic drug
- blocks dopamine |
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Dronabinol
- what kind of drug is it - where does it come from - what does it do |
- antiemetic drug
- get from marijuana - interrupts emetic center |
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Promethazine
- what kind of drug - what does it do - who is it beneficial for |
- antiemetic drug
- histamine 1 blocker - beneficial for hospitalized patients |
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Loperamide
- what kind of drug - whats the one thing to know |
- antidiarrheal agent
- cant into blood brain barrier readily |
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Diphenoxylate
- what kind of drug - whats the one thing to know |
- antidiarrheal agents
- can't get into blood brain barrier readily |
