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33 Cards in this Set

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What are dugs that STIMULATE UTERINE contractions called?
OXYTOCICS
What are drugs that SUPPRESS Contractions called?
TOCOLYTICS
What are the 3 applications of OXYTOCIC drugs?
1. INDUCTION/AUGMENTATION of labor
2. CONTROL Postpardum BLEEDING
3. INCUCE ABORTION
What is the ONE MAJOR use of TOCOLYTIC drugs?
SUPPRESS PRETERM LABOR
What are some TOCOLYTIC (uterine relaxants) drugs?
-MG. SULFATE
-BETA2-SELECTIVE ADRENERGIC AGONIST(Ritodrin}
-Terbutaline{Brethine}
-NIFEDIPINE(procardia, adalat, nifedical)
-Indomethacin (Indocin)
What is the treatment OF CHOICE to treat PREterm Labor?
MG. SULFATE IV
How does Mg. Sulfate work?
Inhibits ACETYLCHOLINE RELEASE @ UTERINE NEUROMUSCULAR JUNCTION.
What else is MG. SULFATE used for?
PREFERRED for PREVENTION of TREATMENT of SEIZURES associated with ECLAMPSIA & PRE-ECLAMPSIA
What should you ASSESS OFTEN if giving MG. SULFATE?
RESPERATIONS
What are some BETA2-SELECTIVE ADRENERGIC AGONIST?
RITODRINE
TERBUTALINE(BRETHINE)
What are the affects of RITODRINE?
It affects BETA CELLS, RELAXES uterus smooth muscles therby DECREASING Frequency and Intensity of contractions.
What are the ADVERSE EFFECTS of RITODRINE?
PULMONARY EDEMA, HYPOTENSTION, HYPERGLYCEMIA, TACHYCARDIA in FETUS.
Which is better for the mother RITODRINE or MG. SULFATE?
MG. SULFATE.
RITODRINE is as effective as MG. SULFATE but poses a MUCH greater risk on the mother.
What is TERBUTALINE(BRETHINE) used for? is it FDA approved?
ASTHMA but used to delay preterm labor(NOT FDA approved)
What is NIFEDIPINE? (procardia, adalat, nifedical) Whats it used for?
CALCIUM CHANNEL BLOCKER--suppress PRETERM Labor
What is INDOMETHICIN(INDOCIN) used for?
-2nd line drug for SUPPRESSING PRETERM labor.
When is INDOMETHICIN(INDOCIN) reserved for?
WOMEN UNRESPONSIVE/INTOLERENT to preferred agents.
What are OXYTOCIC used to do?
STIMULATES uterine contractions, INDUCTION/Augmentation of labor, Control of POSTpartum bleeding, INDUCTION of ABORTION.
What are TOCOLYTIC used for?
SUPPRESS CONTRACTIONS, SUPPRESS PREtem labor.
What are the drugs in the OXYTOCICS family?
OXYTOCIN(PITOCIN),ERGOT ALKALOIDS(ergonovine&methlergonovine), CARBOPROST TROMETHAMINE(HEMABATE)
what kind of hormone is OXYTOCIN(PITOCIN)? Where is OXYTOCIN(PITOCIN) produced?
POLYPEPTIDE hormone produced by the POSTERIOR PITUITARY.
What is OXYTOCIN(PITOCIN) used for?
INDUCE labor, PROMOTE UTERINE CONTRACTIONS, MILK EJECTION, WATER RETENTION(similar to ADH)
What women SHOULD NOT use OXYTOCIN(PITOCIN)?
Women who have active GENITAL HERPES, uterine rupture possibility.
What should you do if while taking OXYTOCIN(PITOCIN) contractions are >60sec.?
DISCONTINUE!!
What are the ADVERSE effects of taking OXYTOCIN(PITOCIN)?
WATER INTOXICATION d/t anti diuretic affects.
What are ERGOT ALKALOIDS(ergonovine&methylergonovine used for?
POSTPARTUM BLEEDING, MIGRAINE,AUGMENTAION of labot(NOT recommended)
What are teh ADVERSE effects of IV ERGOT ALKOLOIDS(ergonovine&methylergonovine)?
HTN d/t constiction of arterioler & veins.
What are ERGOT ALKALOIDS reserved for?
HEMORRHAGIC EMERGENCIES.
When in ERGONOVINE used?
In the presence of BOGGY uterus & VAGINAL bleeding.
What is the preferred agent used for controlling POSTPARTUM HEMORRHAGE?
CARBOPROST THROMETHAMINE(hemabate)--causes INTENSE uterine contractions
what are the ADVERSEeffects of CARBOPROST TROMETHAMINE(hemabate)
GI reactions, V&D, Fever, Vasoconstrition, Constriction of Bronchi.
What is DINOPROSTONE(Prepidil/Ceridil) used for?
Promote Cervical Ripining BEFORE INDUCTION of labor w/ Oxytocin(Pitocin).
What are the 3 different types of DINOPROSTONE(prepidil/Cervidil)?
DINOPROSTONE GEL
DINOPROSTONE VAGINAL INSERTS(cervidil)
MISOPROSTOL(cytotec)-NOT APPROVED for CERVICAL RIPENING