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14 Cards in this Set
- Front
- Back
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Episodic or chronic tension headache?
1. Tricyclic antidepressant like Amitriptyline 2. OTC NSAIDs 3. Mixed NSAID/opioid 4. Muscle relaxants like Metaxalone or Cyclobenzaprine 5. Botox |
1. Chronic
2. Episodic 3. Episodic 4. Chronic 5. Chronic |
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_____ headaches are the most common form of chronic headaches.What are they due to?
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Rebound; overuse of meds
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The effective serotonin agonists have a high affinity for what two receptors (which makes their involvement in both theories plausible)?
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5HT1B and 5HT1D
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What are the two theories of serotonin in migraines?
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1. These agents block the vasodilatory phase of the HA
2. They bind presynaptic receptors that modulate neurotransmitter release from nerve terminals |
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T or f: aspirin and acetaminophen work for migraines
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T
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What's the role of adding caffeine to an NSAID for migraines?
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Antagonizes adenosine receptors (build up of adenosine occurs in migraines)
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What's the role of Butalibal when added to an NSAID for migraine tx?
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Short acting barbiturate can be added to formulations as an anxiolytic and sedative
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T or f: serotonin agonists are effective for rapid relief for acute headaches (migraine)
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T
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What are ergotamines/dihydroergotamines and triptans?
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Serotonin agonists
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What's inside of Cafergot or Wigraine?
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An ergotamine and caffeine
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What are the first line agents to abort acute mild to moderate migraines?
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Triptans
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T or f: recurring or rebound headaches may be more common in ergotamines than triptans
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F...other way around
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Triptans are contraindicated in people with what disease?
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Vascular (cause vascular spasms)
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What is the most used prophylactic tx for migraines?
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Beta blockers (Propranolol, Timolol)
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