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Chlorothiazide (Diuril)
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Antihypertensive, agent for reducing edema-Thiazide diuretic
*excess loss of water/electrolytes *thirst, weakness. lethargy, muscle cramping, hypotension, and tachycardia *pt taking digoxion should be monitor for hypokalemia *increase potassium intake Contraindications: *anuria,hypokalemia, severe hepatic or renal impairment, and hypersensitivity to sulfonamides Interactions: *addictive effects *insulin less effective *cholestyramine and colestipal decrease the absorption LAB: *may increase serum amylase and SBP retention *may decrease protein-bound iodine and interfere with urine steroid FOOD: *absorption increased when taken with food *licorice and aloe may worsen hypokalemia *ginko biloba may increase blood pressure |