Pharm Test 1 Drugs

Front 1

- Indications: Severe pain, Pulmonary Edema, and pain associated with MI
- Binds to opiate receptors in the CNS; alters the perception and response to painful stimuli while producing CNS depression
- Schedule II; Pregnancy Cat C

Back 1

Morphine

Front 2

- CI: hypersensitivity and known alcohol intolerance; cautious if use if: head trauma, geriatrics, OB, peds, MAOIs, ETOH
- AR: respiratory depression, confusion, sedation, hypotension, constipation
- Patient teaching: Tell family not to give to sleeping pt.

Back 2

Morphine

Front 3

- CI: hypersensitivity, known ETOH tolerance, pregnancy
- AR: confusion, sedation, hypotension, constipation
- Schedule 2, Pregnancy Cat C

Back 3

Methadone

Front 4

- Severe pain, suppresses withdrawal symptoms in opioid detoxification
- Binds to opiate receptors in the CNS; alters perception and response to painful stimuli while producing CNS depression, decreases severity of pain

Back 4

Methadone

Front 5

- Moderate or severe pain (alone or with nonopioid); anesthesia adjunct, analgesic during labor; pre-op sedation, rigors
- Binds to opiate receptors in the CNS; alters the perception and response to painful stimuli while producing generalized CNS depression

Back 5

Demerol (Meperidine)

Front 6

- CI: hypersensitivity, pregnancy/lactation, recent MAO therapy
- AR: seizures, constipation, sedation, hypotension, N/V

Back 6

Demerol (Meperidine)

Front 7

- Antidote
- Reversal of CNS depression and respiratory depression because of suspected opioid OD
- Completely blocks the effects of opioids, including CNS and respiratory depression, without producing any agonist effects

Back 7

Narcan

Front 8

- CI: hypersensitivity
- AR: hypertension/hypotension, ventricular fibrillation, ventricular tachycardia, N/V

Back 8

Narcan

Front 9

- Moderate to severe pain, analgesic during labor, sedation before surgery, and supplement to balance anesthesia (Mixed agonist/antagonist)
- Binds to opiate receptors in the CNS, alters the perception and response to painful stimuli while producing generalized CNS depression

Back 9

Nalbuphine

Front 10

- CI: hypersensitivity, If given to patients addicted to opioids, may produce ACUTE WITHDRAWAL SYNDROME
- AR: dizziness, headache, sedation, dry mouth, N/V, clammy feeling, sweating

Back 10

Nalbuphine (Nubain)

Front 11

- Moderate to severe chronic pain needed continuously for an extended time period; not recommended for post-op, mild, or intermittent pain
- Binds to opiate receptors in the CNS, altering the response to and perception of pain

Back 11

Fentanyl

Front 12

- CI: hypersensitivity, known intolerance, OB/Geri/Peds
- AR:apnea, confusion, sedation, weakness, anorexia, sweating
- Patch worn; children may die from wearing the wrong patch

Back 12

Duragesic (Fentanyl)

Front 13

- Moderate to moderately severe pain
- CI: hypersensitivity, acute-severe sedation with alcohol, OB
- AR: seizure, dizziness, drowsiness, HA, somnolence, constipation, N/V

Back 13

Ultram (Tramadol)

Front 14

ASA o MI/TIA Prevention

Back 14

81-325 mg/day

Front 15

ASA OA/RA

Back 15

2-6g/day

Front 16

ASA Pain/Fever

Back 16

325-650mg/day

Front 17

ASA Rheumatic Fever

Back 17

5-8g/day

Front 18

- Moderate to severe chronic pain needed continuously for an extended time period; not recommended for post-op, mild, or intermittent pain
- Binds to opiate receptors in the CNS, altering the response to and perception of pain

Back 18

Fentanyl

Front 19

- CI: hypersensitivity, known intolerance, OB/Geri/Peds
- AR:apnea, confusion, sedation, weakness, anorexia, sweating
- Patch worn; children may die from wearing the wrong patch

Back 19

Duragesic (Fentanyl)

Front 20

- Moderate to moderately severe pain
- CI: hypersensitivity, acute-severe sedation with alcohol, OB
- AR: seizure, dizziness, drowsiness, HA, somnolence, constipation, N/V

Back 20

Ultram (Tramadol)

Front 21

- Inflammatory disorders: RA, OA, mild to moderate pain (may be combined with oral opiod), fever, prophylaxis of TIA attacks and MI prevention; anti-inflammatory; antipyretic; antiplatelet; (low dose cardioprotective)

Back 21

ASA

Front 22

- Produces analgesia and reduce inflammation and fever by inhibiting the production of prostaglandins; aspirin decreases plately aggregation

Back 22

ASA

Front 23

- CI: hypersensitivity, bleeding disorders, children with viral infections (Reye’s syndrome)
- AR: GI bleeding exfollative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, anaphylaxis, laryngeal, dyspepsia, epigastric distress, heartburn, nausea

Back 23

ASA

Front 24

ASA o MI/TIA Prevention

Back 24

81-325 mg/day

Front 25

ASA OA/RA

Back 25

2-6g/day

Front 26

ASA Pain/Fever

Back 26

325-650mg/day

Front 27

ASA Rheumatic Fever

Back 27

5-8g/day

Front 28

ASA TIA

Back 28

1300MG/DAY

Front 29

- Mild to moderate pain or dysmenorrheal; inflammatory disorders (RA & OA); lowering of fever
- Inhibits prostaglandin synthesis
- CI: hypersensitive, active GI bleeding

Back 29

Advil (Ibuprofen)

Front 30

- AR: GI bleeding, hepatitis, exfollative dermatitis, stevens-johnson syndrome, toxic epidermal necrolysis, allergic rxns, HA, constipation, dyspepsia, N/V

Back 30

Advil

Front 31

- Mild pain, fever (NOT USED FOR ANTI-INFLAMMATORY)
- Inhibits the synthesis of prostaglandins that may serve as mediators of pain and fever, primarily in the CNS

Back 31

Tylenol

Front 32

- AE: hepatic failure, renal failure, blood dyscrasia
- Max 24 hour dose – 4 grams
- AR: hepatic failure, hepatotoxcity, liver or renal disease

Back 32

Tylenol

Front 33

- Antidote to Tylenol
- AR: angioedema, bronchospasm, N/V, pruritis, rash, urticaria

Back 33

Acetylcysteine (mucomyst)

Front 34

- Topical cream
- Blocks substance P
- AR: cough, transient burning

Back 34

Zostrix (capsaicin)

Front 35

- Herbal for osteoarthritis, ischemic heart disease, hyperlipidemia
- May serve as building block of articular cartilage
- CI: pregnancy/lactation
- AR: heartburn, N/V, bleeding, allergic rxns, edema, hair loss

Back 35

chondroitin

Front 36

- Short term management of pain
- AR: GI bleed, exfollative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, anaphylaxis, drowisness

Back 36

Keratolac (Toradol)

Front 37

- Chronic gout! Prevention of attack of gouty arthritis and nephropathy
- Inhibits the production of uric acid
- CI: hypersensitivity, Pregnancy/lactation
- AR: Rash

Back 37

Allopurinal (Zyloprim)

Front 38

- Acute gout!
- CI: pregnancy/lactation, severe renal or GI disease
- AR: agranulocytosis, aplastic anemia, N/V/D

Back 38

Colchicine

Front 39

- Acute treatment of migraines and cluster HA
- CI: pts with ischemic heart disease, uncontrolled HTN, ischemic HD, pregnancy/lactation, concurrent antidepressant use
- AR: dizziness, vertigo, tingling, warm sensation, injection site reaction

Back 39

Sumatriptan (Imitrex)

Front 40

- Vascular HA, migraine, cluster HA
- CI: serious infections, PVD, CV dx. Uncontrolled HTN, pregnancy/lactation
- AR: rhinitis, abdominal pain, MI, HTN, neuro changes, N/V, extremity stiffness, muscle pain, numbness/tingling

Back 40

DHE 45

Front 41

- Vascular HA, migraine, cluster HA
- AR: Abdomin pain, MI, HTN, neurological changes
- CI: ischemic heart, uncontrolled HTN, PVD, renal or liver disease
o Larger doses may cause vasodilation

Back 41

Ergotamine (Ergostat)