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25 Cards in this Set
- Front
- Back
composed of the adrenal cortex, and the adrenal medulla
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adrenal gland
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secretes cateccholamines: epinephrine(fight/flight response) & norepinephrine( constrict blood vessels and increase B/P and glucose levels
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adrenal medula
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epinephrine controls:
norepinephrine cotrols: both are secreted by the: |
flight/ fight response; constrict blood vessels and increase B/P and glucose leves; adrenal medula
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secretes corticosteroids such as gluccocorticoids
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adrenal cortex
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oversecretion of adrenal hormones lead to:
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cushing's syndrome
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Cushing syndrome S/S
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Na& fluid retention, hyperglycemia, CNS irritability, thin extremities, GI distress, increase acid, osteoparosis, thick skin
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undersecretion of adrenal hormones lead to:
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addison's disease
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addison's disease S/S
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hypoglycemia, bronze pigmentation of the skin, change in the distribution of body hair, GI disturbance, weakness, weight loss, postural hypotention
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adrenal drug:
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Gluccocorticoids ( topical, systemicc, inhaled, nasal)
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Glucocorticoids drugs
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fluticasone propionate ( Flonase), hydrocortisone (several formulations),
cortisone, methylprensolone (Solu-Medrol) prednisone (Deltasone, Sterapred, Liquid Pred) |
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Glucocorticoids__ or help___ inflammatory and immune response.
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inhibit; help
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adrenal drugs indications:
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cerebral edema, dermatologic disease, GI disease, Exacerbation of chronic respiratory illnesses, such as asthma and COPD
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Glucocortioids: administration by inhalation for control of _____.
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steroid responsive bronchospastic states.
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Glucocortioids: administered nasally for____.
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rhinitis and to prevent the recurrence of polyps after surgical removal.
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Glucocoricoids: administered topicallly for___.
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inflammation of the eye, ear, and skin.
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oral corticosteroids should be taken when?
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in the morning to minimize adrenal suppression.
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adrenal steroid inhibitors, used in the treatment of Cushing's syndrome, metastatic, breast cancer, and adrenal cancer.
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aminoglutethimide (Cytadren), antiadrenal
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containdications for antiadrenals:
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ulcer disease( because it can cause the stomach to perforate) diabetes, cardiac/renal/liver dysfunction.
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antiadrenals adverse effects: cardiovascular, CNS
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cardiovascular: heart failure, cardiac edema, hypertension, all caused by electrolyte imbalances (hypokalemia, hypernatremia),
CNS: convusions, "steroid psychosis" |
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antiadrenals adverse effects: endocrine,GI
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endocrine: cushing's syndrome, menstral irregularities, carboydrate intolerance
GI: peptic ulcers with possible perforation |
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antiadrenals adverse effects: integumentary,
ocular, other? |
poor wound healing, increased intraocular pressure, glaucoma, weight gain
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systemic forms of antiadrenal drugs may be give by oral, IM, IV, or rectal routs but NOT
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subcut
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after using an orally inhaled corticosteroid, instruct the patient to____to prevent possible _____.
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rinse their mouths; oral fungl infetions
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patients should be taught to take all adrenal medications___ usually____ with___.
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at the same time every day; in the morning; with meals or food.
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patients should not take with (3) with corticosteroids due to the possible development of____.
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alcohol, NSAIDS, asprin; gastric ulcers
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