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41 Cards in this Set

  • Front
  • Back
epinephrine, NE, isoproterenol, dopamine, and dobutamine are all________________
catecholamines
catecholamines are_____________________
sympathomimetics
name 5 catecholamines
EPI, NE, Isoproterenol, dopamine, dobutamine
what receptors does epinephrine act on?
alpha-1, alpha-2, beta-1, beta-2 adrenergics
what receptors does NE work on?
alpha-1, alpha-2, beta-1 adrenergics
what receptors does isoproterenol work on?
beta-1 = beta-2 adrenergics
what receptors does dopamine work on?
D1 = D2, D1 and D2 more than beta, beta more than alpha
what receptors does dobutamine work on?
beta-1 > beta-2
which catecholamines are agonists to alpha-adrenergic receptors
EPI, NE > dopamine
which catecholamines are agonists to beta-1 adrenergic receptors
EPI, NE, Isoproterenol, dopamine, dobutamine
which catecholamines are agonists to beta-2 adrenergic receptors
EPI, isoproterenol, dopamine and dobutamine (less)
what is epinephrine used to treat?
anaphylaxis, open-angle glaucoma, asthma, hypotension
what is norepinephrine used to treat?
hypotension (but decreases renal perfusion)
what is isoproterenol used to treat?
AV block, asthma
what is dopamine used to treat
shock with renal failure, heart failure
what is dobutamine used to treat
shock, heart failure
what catecholamine is used to treat anaphylaxis
epinephrine ("EPI-pen")
what catecholamines are used to treat hypotension
EPI, NE
what catecholamine is used to treat asthma
epinephrine
what catecholamine is used to treat AV block
isoproterenol
what catecholamines are used to treat shock
doapmine, dobutamine
what is the action of amphetamine
indirect general adrenergic agonist, releases stored catecholamines
what is the action of ephedrine
indirect general adrenergic agonist, releases stored catecholamines
what is amphetamine used to treat
narcolepsy, obesity, attention deficit disorder
what is ephedrine used to treat
nasal decongestion, urinary incontinence, hypotension
name three sympathomimetic drugs used to treat hypotension
epinephrine, norepinephrin, ephedrine
what is the action of phenylephrine
adrenergic agonist, alpha-1 > alpha-2
what is the action of albuterol
adrenergic agonist, beta-2 >beta-1
what is the action of terbutaline
adrenergic agonist, beta-2 >beta-1
what is phenylephrine used for?
pupil dilator, vasoconstriction, nasal decongestion
what sympathomimetics are used to treat nasal congestion
ephedrine, phenylephrine
what is the mechanism of cocaine
indirect general adrenergic agonist, catecholamine uptake inhibitor
what is the action of cocaine
vasoconstriction, local anesthesia
what is the mechanism of clonidine
centrally acting alpha-adrenergic agonist, decreases central adrenergic outflow
what drug has the same mechanism as amphetamine
ephedrine
what is the mechanism of alpha-methyldopa
centrally acting alpha-adrenergic agonist, decreases central adrenergic outflow
what drug has the same mechanism as clonidine
alpha-methyldopa
what are clonidine and alpha-methyldopa used to treat
hypertension, especially in renal disease because they do not decreased blood flow to the kidney
what sympathomimetic is used to treat urinary incontinence
ephedrine
what sympathomimetic is used to treat attention deficit disorder
amphetamine
what sympathomimetic is used to treat narcolepsy
amphetamine