Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/29

Click to flip

29 Cards in this Set

  • Front
  • Back
  • 3rd side (hint)
-cillin
Penicillins (class of Beta Lactams)
Inhibit transpeptidation, cell wall synthesis.
=Natural
Peni- (G,V)
=Penicillinase resistent
Methi-
Cloxa-
=extended range
Ampi-
Amoxi-
=psudomonal
Carbeni-
Ticar-
Piper-
Cef-
Cephalosporins (class of Beta Lactams)
Inhibit transpeptidation, cell wall synthesis.
1st Gen
-azolin
2nd
-otetan
-otoxitin
-uroxime
also Loracarbef
3rd
-triazone
-trazidime
-operazone
4th
-epime
-penem
Carbapenems (class of Beta Lactams)
Inhibit transpeptidation, cell wall synthesis.
Imi-
Mero-
Erta-
-cycline
Tetracyclines/Glycylcylcine
Bind 30S and inhibit bacterial protein synthesis
=Tetra
Tetra-
Doxy-
=Glycyl
Tige-
-THROmycin
Macrolides/Ketolides.
Bind 50S and inhibit bacterial protein synthesis.
=Macrolides
Ery-
Clari-
Azi-
=Ketolide
Teli-
-oxazole
Sulfonamides.
Inhibit dihydropteroate synthase. (Trimethoprim inhibits dhpt reductase)
Prevent folate synthese, ergo nucleic acid synthesis
Sulfis-
Sulfameth-
-floxacin
Fluoroquinolones.
Inhibit DNA gyrase.
Bc G-
Cipro-
Lexo-
Rifa-
Rifamycins.
Inhibit RNA synthesis.
-mantadine
Inhibits viral uncoating via M2 protein.
Treats Influenza A
A-
Ri-
-amivir
Block viral budding.
Inhibits viral neuraminidase, prevents cleavage of sialic acid.
Treats Influenza A & B.
Zan-
Oselt-
-ciclovir
-cyclovir
Guanosine (guanine nucleoside) analog.
Acyclovirs and analogs treat Hepres simplex 1& 2 and varicella zoster.
Ganciclovir is used for CMV.
Acy-
Valacy-
Penci-
Famci-

Ganci-
-cavir
Guanosine analog nucleoSide reverse transcriptase inhibitors.
Abacavir = HIV
Entecavir = HBV
Aba-
Ente-
-fovir
NucleoTide reverse transcriptase inhibitors.
Tenofovir = HIV
Cidofovir = CMV
Adefovir = HBV
Teno-
Cido-
Ade-
-navir
HIV protease inhibitors.
Block cleavage of gag-pol precursor.
Amprenavir/Fosamprenavir
Atazanavir
Darunavir
Indinavir
Lopinavir
Nelfinavir
Ritonavir
Saquinavir
Tipranavir
-conazole
Azoles (antifungal).
Inhibit 14-alpha-demethylase (a P-450).
Prevent ergosterol synthesis
Flu-
Intra-
Keto-
Poso-
Vori-
-afine
Allylamines.
Inhibit fungal squalene oxidase.
Naft-
Terbin-
Buten-
-fungin
Echinocandins.
Inhibit glucan synthase. Glucan in used in fungal cell wall.
Caspo-
Mica-
-mustine
Chloroethyl nitrosoureas.
Heterobifunctional alkylating agents for cancer chemo.
Also can cause DNA crosslinking and carbamoylation of proteins.
CNS available.
Car-
Lo-
-platin
Platinum coorditing alkylating agents for cancer chemo.
Testicular, ocarian, heand and neck cancers.
Cis-
Oxali-
Carbo-
Vin-
Vinca Alkaloids (from plants).
Bind to tubulin, favor depolymerization.
Tox: Granulocytopenia.
-cristine
-blastine
-orelbine
-taxel
Taxanes: diterpene antineoplastics from western yew tree.
Bind to tubulin, make it super stable (inhibit dynamic processes like mitosis).
Tox: neutropenia, mucositis.
Pacli-
Doce-
-poside
Epipodophyllotoxins from mandrake plant.
Inhibit topoisomerase II.
Treat Hodgkin's, diffuse histiocytic lymphoma and SCC of lung.
Tox: leukopenia, thrombocytopenia
Eto-
Teni-
-tecan
Camptothecins.
Inhibit topoisomerase I.
Irino: metastatic colon cancer
Topo: ovarian and SCC of lung
Irino-
Topo-
-rubicin
Antrhacycline antibiotics used in cancer chemotherapy.
Mech: DNA intercalation/single stranded breaks.
Dauno-
Doxo-
-tinib
Tyrosine kinase inhibitors
Ima: Blocks c-abl kinase (translocated to bcr region of ch22).
Treats CML and Ph+ ALL

Erlo, Gefi: inhibits EGF receptor.
Treats non-SCC of lung and pancreatic cancer
Ima-
Erlo-
Gefi-
-mab (chemo)
Monoclonal antibodioes
Ceruxi: EGF receptor - head, neck, metastatic colon cancer
Trastuzu: p185-her2 positive breast cancer.
Bevacizu: VEGF receptor - inhibits angiogenesis in lung, colon cancer.
Rituxi: anti-CD20 - non-Hodgkins B cell lymphoma
Gemtuzu: anti CD33
Ceruxi-
Trastuzu-
Bevacizu-
Rituxi-
Gemtuzu-
-trozole
Selective & reversible aromatase inhibitors.
Treat breast cancer.
Used for only postmenopausal women.
Anas-
Le-
also Exemestane
-quine
Malarials
Meflo-
Chloro-
Also Quinine and Quindidine
-bendazole
Benzimadozoles.
Bind beta-tubulin, inhibit microtubule polymerization.
Anti-Nematodes: T. trichiura, Ascaris, Capillariasis, Necator americanus
Al-
Me-
Thia-