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15 Cards in this Set
- Front
- Back
A side effect is formally defined as _______________________________.
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a nearly unavoidable secondary drug effect produced at therapeutic doses.
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____________________ is an adverse drug reaction caused by excessive
dosing. |
Toxicity
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Most serious reactions are caused by one drug ________________, whereas
other drugs are noted for causing allergic reactions including the __________________. |
penicillin / nonsteroidal anti-inflammatory drugs (eg, aspirin) and the sulfonamide group of compounds, which includes certain diuretics, antibiotics, and oral hypoglycemic agents.
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An uncommon drug response resulting from a genetic predisposition is call an __________
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idiosyncratic effect
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A disease caused by a drug is called a(n)______________________.
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iatrogenic disease
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A state in which the body has adapted to prolonged drug exposure in such a
way that an abstinence syndrome will result if drug use is discontinued is _____________________. |
physical dependence
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Drug-induced birth defects are referred to as ______________________.
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teratogenic effect
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The patient’s last line of defense against medication made by others is
the___________________________. |
nurse
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Dosage adjustments based on ________________ provide a more precise
means of controlling drug responses than do adjustments based on weight alone. |
body surface area
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Drug sensitivity varies with age. In ______________, heightened drug
sensitivity is the result of ___________________. In the _________, heightened sensitivity results largely from _____________________. |
very young / organ immaturity / elderly / organ degeneration
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Why do we know much about gender-related differences and drug therapy?
_________________________ |
Because all testing in the past has been done on men.
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Perhaps the most important example of an altered drug effect occurring in
response to electrolyte imbalance involves digoxin and __________________. |
potassium
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Decreased responsiveness to a drug as a result of repeated drug administration
is called ___________________. |
tolerance
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The type of tolerance associated with long-term administration of drugs such as
morphine and heroin is _______________________. |
pharmacodynamic tolerance
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A form of tolerance that can be defined as a reduction in drug responsiveness
brought on by repeated dosing over a short time is called _______________. |
tackyphylaxis
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