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15 Cards in this Set
- Front
- Back
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Reduction in one or more of what is considered anemia? |
Hemoglobin, Hematocrit, RBC count |
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Factors that create erythrocytes: |
GMCSF, IL-3, Epo, SCF |
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What effects the exchange of oxygen |
PH and partial pressure of CO2 |
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reticulocyte count |
reflects rate of blood cell production; responds to therapy in about 5 days. |
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signs and symptoms of anemia |
dyspnea at rest, fatigue, bounding pulses, palpitations, low BP, weakness (severe = fainting, CP, angina, MI) |
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MCV >100/fL - Macrocytic causes |
B12 deficiency, folic acid, drug induced BM toxicity....affects DNA synthesis |
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MCV 81-99 - Normocytic Anemia causes |
Acute Blood loss, hemolytic anemia, chronic disease |
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MCV <80 Microcytic anemia causes |
Iron deficiency, chronic disease, |
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Iron deficiency anemia cells are... |
hypochromic microcytic |
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Causes of iron deficiency anemia |
Diet, Failure to absorb iron salts, pregnancy, Atransferrinemia, Failure to utilize, blood loss |
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Which labs increase and which ones decrease in iron deficiency anemia |
Everything goes down (MCV, MCH, MCHH, serum iron, ferritin) EXCEPT TIBC is increased |
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What can you add to you iron drug to increase its effectiveness? |
Vitamin C (asorbic acid) to increase by 30% |
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How much elemental iron do you want per day? |
200-400 mg |
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Ferrous Sulfate ADRs |
GI (nausea, constipation, diarrhea, black tarry stool, cramps) Toxicity- Iron poisoning from it building up in organs like pancreas...in acute for babies and chronic adults from hemochromatosis |
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Iron Deficiency Anemia Drug |
Ferrous Sulfate: 325 mg one tablet three times a day with/or after meals |
