Pharm Oneliners Sets Of 50 Part 9-7

Front 1

Site of action of loop diuretics

Back 1

Thick ascending limb

Front 2

SE of loop (furosemide) diuretics (3)

Back 2

Hyperuricemia, hypokalemia and ototoxicity

Front 3

Aminoglycosides used with loop diuretics potentiate adverse effect

Back 3

Ototoxicity

Front 4

Loops lose and thiazide diuretics retain

Back 4

Calcium

Front 5

MOA of thiazide diuretics

Back 5

Inhibit Na+/Cl- cotransport

Front 6

Site of action of thiazide diuretics

Back 6

Work at early distal convoluted tubule

Front 7

Class of drugs that may cause cross-sensitivity with thiazide diuretics

Back 7

Sulfonamides

Front 8

SE of thiazide (HCTZ) diuretics (3)

Back 8

Hyperuricemia, hypokalemia and hyperglycemia

Front 9

Potassium sparing diuretics inhibit

Back 9

Na+/K+ exchange

Front 10

Diuretic used to treat primary aldosteronism

Back 10

Spironolactone

Front 11

SE of spironolactone (3)

Back 11

Gynecomastia, hyperkalemia, and impotence

Front 12

Osmotic diuretic used to treat increased intracranial pressure

Back 12

Mannitol

Front 13

Section: Antidiuretic hormone (ADH) agonist and antagonist

Front 14

ADH agonist used for pituitary diabetes insipidus

Back 14

Desmopressin (DDAVP)

Front 15

Used for SIADH

Back 15

Demeclocycline

Front 16

SE of demeclocycline

Back 16

Bone marrow and teeth discoloration for children under 8 years of age

Front 17

Antiarrhythmic agents

Front 18

MOA of class I A (eg. Procainamide), class IB (eg. Lidocaine), and class IC (eg. Flecainide) antiarrhythmics

Back 18

Sodium channel blockers

Front 19

SE of procainamide

Back 19

Lupus-like syndrome

Front 20

Limiting side effect of Quinidine

Back 20

Prolongs QT interval

Front 21

Other side effects of Quinidine (2)

Back 21

Thrombocytopenic purpura, and CINCHONISM

Front 22

Major drug interaction with Quinidine

Back 22

Increases concentration of Digoxin

Front 23

DOC for management of acute ventricular arrhythmias

Back 23

Amiodarone

Front 24

DOC for digoxin induced arrhythmias

Back 24

Phenytoin

Front 25

SE of phenytoin

Back 25

Gingival hyperplasia

Front 26

Class of anti-arrhythmics that has a pro-arrhythmic effect (CAST trial), therefore are used as last line agents

Back 26

Class IC (flecainide, propafenone, moricizine)

Front 27

Class II antiarrhythmics are

Back 27

B-blockers

Front 28

Antiarrhythmic that exhibits Class II and III properties

Back 28

Sotalol

Front 29

Side effect of sotalol

Back 29

prolongs QT and PR interval

Front 30

Used intravenously for acute arrhythmias during surgery

Back 30

Esmolol

Front 31

Anti-arrhythmics that decrease mortality

Back 31

B-blockers

B savin your life

Front 32

MOA of class III antiarrhythmics

Back 32

Potassium channel blockers

Front 33

Class III antiarrhythmic that exhibits properties of all 4 classes

Back 33

Amiodarone

Front 34

Specific pharmacokinetic characteristic of amiodarone

Back 34

Prolonged half-life, up to six weeks

Front 35

Antiarrhythmic effective in most types of arrhythmia

Back 35

Amiodarone

Front 36

SE of Amiodarone (6)

Back 36

Cardiac dysfunction,
photosensitivity, skin (blue smurf syndrome),
Pulmonary fibrosis,
thyroid and corneal deposits

Front 37

MOA of class IV antiarrhythmics

Back 37

Calcium channel blockers

Front 38

Life threatening cardiac event that prolong QT leads to

Back 38

Torsades de pointes

Front 39

Agent to treat torsades de pointes

Back 39

Magnesium sulfate

Front 40

Drug used supraventricular arrhythmias

Back 40

Digoxin

Front 41

DOC for paroxysmal supraventricular tachycardia (PSVT)

Back 41

Adenosine

Front 42

Adenosine's MOA

Back 42

Activation on an inward K+ current and inhibition of Ca++ current resulting in marked HYPERPOLARIZATION

Front 43

Anti-arrhythmic with 15 second duration of action

Back 43

Adenosine

Front 44

Vasodilators and treatment of angina

Front 45

MOA of sildenafil (Viagra)

Back 45

Inhibits phosphodiesterase-5, enhancing effects of nitric oxide-activated increases in cGMP

Front 46

Drugs used in the management of angina (4)

Back 46

Aspirin, Nitrates, CCB, and Beta blockers

Front 47

Aspirin reduces mortality in unstable angina by

Back 47

Platelet aggregation inhibition

Front 48

MOA of nitrates (3 parts)

Back 48

Relax vascular smooth muscle,
at low doses dilate veins and
at high doses dilate arterioles

Front 49

Nitrate used for acute anginal attacks

Back 49

Nitroglycerin sublingual tablets

Front 50

Nitrate used to prevent further attacks

Back 50

Oral and transdermal forms of nitroglycerin