Pharm Oneliners Sets Of 50 Part 9-1

Front 1

Agents used in Tourette's dx

Back 1

Haloperidol or pimozide

Front 2

Chelating agent used in Wilson's disease

Back 2

Penicillamine

Front 4

Antipsychotics

Front 5

Extrapyramidal dysfunction is more common with these agents, which block this subtype of dopamine receptor

Back 5

Older antipsychotic agents, D2 receptors

Front 6

MOA of neuroleptics

Back 6

Dopamine blockade

Front 7

Side effects occuring in antipsychotics that block dopamine (7)

Back 7

Hyperprolactinemia, amenorrhea, galactorrhea,
confusion, mood changes,
decreased sexual interest, and weight gain

Front 8

Antipsychotics that reduce positive symptoms only

Back 8

Older antipsychotics

Front 9

Newer atypical antipsychotics that also improve some of the negative symptoms and help acute agitation

Back 9

Olanzapine, aripiprazole, and sertindole

Ol Ari is sertinly negative

Front 10

Antipsychotic used in the treatment of psychiatric symptoms in patients with dementia

Back 10

Risperidone

Front 11

Atypical antipsychotic causing high prolactin levels

Back 11

Risperidone

Front 12

Newer atypical antipsychotic used for bipolar disorder, known to cause weight gain, and adversely affect diabetes

Back 12

Olanzapine

Front 13

Antipsychotic agent more frequently associated with extrapyramidal side effects that can be treated with benzodiazepine, diphenhydramine or muscarinic blocker

Back 13

Haloperidol

Front 14

Drug used in neuroleptic malignant syndrome

Back 14

Dantrolene

Front 15

Agents may exacerbate tardive dyskinesias (may be irreversible and there is no treatment)

Back 15

Muscarinic blockers

Front 16

Antipsychotic having the strongest autonomic effects

Back 16

Thioridazine

Front 17

Antipsychotic having the weakest autonomic effects

Back 17

Haloperidol

Front 18

Only phenothiazine not exerting antiemetic effects, can cause visual impairment due to retinal deposits, and high doses have been associated with ventricular arrhythmias

Back 18

Thioridazine

Front 19

Agent having no effect on D2 receptors, blocks D4, reserved for resistant schizophrenia, and can cause fatal agranulocytosis

Back 19

Clozapine

Front 20

Anti-psychotic not shown to cause tardive dyskinesia

Back 20

Clozapine

Front 21

Anti-psychotics available in depot preparation

Back 21

Fluphenazine and haloperidol

Front 22

Antipsychotics with reduced seizure threshold

Back 22

Low-potency typical antipsychotics and clozapine

Front 23

Antipsychotics that cause orthostatic hypotension and QT prolongation

Back 23

Low potency APs and risperidone

Front 24

Antipsychotic with Increased risk of developing cataracts

Back 24

Quetiapine

Qatar-acts

Front 25

Lithium

Front 26

Major route of elimination for Lithium

Back 26

Kidneys

Front 27

Patients being treated with lithium, who are dehydrated, or taking diuretics concurrently, could develop

Back 27

Lithium toxicity

Front 28

Drug increases the renal clearance hence decreases levels of lithium

Back 28

Theophylline

Front 29

Lithium is associated with this congenital defect
and is contraindicated in

Back 29

Cardiac anomalies and is contraindicated in pregnancy or lactation

Front 30

DOC for bipolar affective disorder

Back 30

Lithium

Front 31

Concern using lithium

Back 31

Low therapeutic index

Front 32

SE of lithium (6)

Back 32

Tremor, sedation, ataxia, aphasia, thyroid enlargement, and reversible diabetes insipidus

Front 33

Antidepressants

Front 34

Example of three antidepressants that are indicated for obsessive compulsive disorder

Back 34

Clomipramine, fluoxetine and fluvoxamine

Front 35

Neurotransmitters affected by the action of antidepressants

Back 35

Norepinephrine and serotonin

Front 36

Usual time needed for full effect of antidepressant therapy

Back 36

2 to 3 weeks

Front 37

Population group especially sensitive to side effects of antidepressants

Back 37

Elderly patients

Front 38

All antidepressants have roughly the same efficacy in treating depression, agents are chosen based on these criterion

Back 38

Side-effect profile and prior pt response

Front 39

Well-tolerated and are first-line antidepressants (3)

Back 39

SSRI's, bupropion, and venlafaxine

Front 40

Monoamine oxidase inhibitors (MAOI)

Front 41

Most useful in patients with significant anxiety, phobic features, hypochondriasis, and resistant depression

Back 41

Monamine oxidase inhibitors

Front 42

Condition will result from in combination of MAOI with tyramine containing foods (ex. wine, cheese, and pickled meats)

Back 42

Hypertensive crisis

Front 43

MAOI should not be administered with SSRI's or potent TCA's due to development of this condition

Back 43

Serotonin syndrome

Front 44

Tricyclic antidepressants (TCA)

Front 45

Sedation is a common side effect of these drugs, they lower seizure threshold, uses include BAD, acute panic attacks, phobias, enuresis, and chronic pain and their overdose can be deadly

Back 45

Tricyclic antidepressants (TCA)

Front 46

Three C's associated with TCA toxicity

Back 46

Coma, Convulsions, Cardiac problems (arrhythmias and wide QRS)

Front 47

Agents having higher sedation and antimuscarinic effects than other TCA's

Back 47

Tertiary amines

Front 48

TCA used in chronic pain, a hypnotic, and has marked antimuscarinic effects

Back 48

Amitriptyline

Front 49

TCA used in chronic pain, enuresis, and ADD

Back 49

Imipramine

Front 50

TCA with greatest sedation of this group, and marked antimuscarinic effects, used for sleep

Back 50

Doxepin