Pharm Oneliners Sets Of 50 Part 8

Front 1

Alcohols

Front 2

Agent that is metabolized to acetaldehyde by alcohol dehydrogenase and microsomal ethanol-oxidizing system (MEOS)

Back 2

Ethanol

Front 3

Agent with zero-order kinetics

Back 3

Ethanol

Front 4

Rate limiting step of alcohol metabolism

Back 4

Aldehyde dehydrogenase

Front 5

System that increases in activity with chronic ethanol exposure and may contribute to tolerance

Back 5

MEOS

Front 6

Enzyme that metabolizes acetaldehyde to acetate

Back 6

Aldehyde dehydrogenase

Front 7

Agents that inhibit aldehyde dehydrogenase (4)

Back 7

Disulfiram, metronidazole, certain sulfonylureas and cephalosporins

Front 8

Agent used in the treatment of alcoholism, if alcohol is consumed concurrently, acetaldehyde builds up and results in nausea, headache, flushing, and hypotension

Back 8

Disulfiram

Front 9

The most common neurologic abnormality in chronic alcoholics

Back 9

Peripheral neuropathy (also excessive alcohol use is associated with HTN, anemia, and MI)

Front 10

Agent that is teratogen and causes a fetal syndrome

Back 10

Ethanol

Front 11

Agent that is the antidote for methanol overdose (2)

Back 11

Ethanol, fomepizole

Front 12

Drug that inhibits alcohol dehydrogenase and is used in ethylene glycol exposure

Back 12

Fomepizole

Front 13

Anti seizure Drugs

Front 14

Most frequent route of metabolism of seizure drugs

Back 14

Hepatic enzymes

Front 15

Mechanisms of action for Phenytoin, Carbamazepine, Lamotrigine

Back 15

Sodium channel blockade

Front 16

MOA for benzodiazepines and barbiturates

Back 16

GABA-related targets

Front 17

MOA for Ethosuximide

Back 17

Calcium channels

Front 18

MOA for Valproic acid at high doses

Back 18

Affect calcium, potassium, and sodium channels

Front 19

Drugs of choice for generalized tonic-clonic and partial seizures

Back 19

Valproic acid and Phenytoin

Val-partial, Pheny-tonic

Front 20

DOC for febrile seizures

Back 20

Phenobarbital

Front 21

Drugs of choice for absence seizures (2)

Back 21

Ethosuximide and valproic acid

Front 22

Drug of choice for myoclonic seizures

Back 22

Valproic acid

Front 23

Drugs of choice for status epilepticus (2)

Back 23

IV diazepam for short term (acute) treatment; phenytoin for prolonged therapy

Front 24

Drugs that can be used for infantile spasms

Back 24

Corticosteroids

Front 25

Anti-seizure drugs used also for bipolar affective disorder (BAD) (4)

Back 25

Valproic acid, carbamazepine, phenytoin and gabapentin

Front 26

Anti-seizure drug used also for Trigeminal neuralgia

Back 26

Carbamazepine

Front 27

Anti-seizure drug used also for pain of neuropathic orgin

Back 27

Gabapentin

Front 28

Anti-seizure agent that exhibits non-linear metabolism, highly protein bound, causes fetal hydantoin syndrome, and stimulates hepatic metabolism

Back 28

Phenytoin

Front 29

SE of phenytoin (4)

Back 29

Gingival hyperplasia, nystagmus, diplopia and ataxia

Front 30

Anti-seizure agent that induces formation of liver drug-metabolism enzymes, is teratogen and can cause craniofacial anomalies and spina bifida

Back 30

Carbamazepine

Front 31

Anti seizure agent that inhibits hepatic metabolism, is hepatotoxic and teratogen that can cause neural tube defects and gastrointestinal distress

Back 31

Valproic acid

Front 32

Laboratory value required to be monitored for patients on valproic acid

Back 32

Serum ammonia and LFT's

Front 33

SE for Lamotrigine

Back 33

Stevens-Johnson syndrome

Front 34

SE for Felbamate

Back 34

Aplastic anemia and acute hepatic failure

Front 35

Anti-seizure medication also used in the prevention of migraines

Back 35

Valproic acid

Front 36

Carbamazepine may cause

Back 36

Agranulocytosis

Front 37

Anti-seizure drugs used as alternative drugs for mood stabilization (4)

Back 37

Carbamazepine, gabapentin, lamotrigine, and valproic acid

Front 38

General Anesthetics

Front 39

MOA of general anesthetics

Back 39

Most are thought to act at GABA-A receptor - chloride channel

Front 40

Inhaled anesthetic with a low blood/gas partition coefficient

Back 40

Nitrous oxide

Front 41

Inversely related to potency of anesthetics

Back 41

Minimum alveolar anesthetic concentration (MAC)

Front 42

Inhaled anesthetics metabolized by liver enzymes which has a major role in the toxicity of these agents (2)

Back 42

Halothane and methoxyflurane

Front 43

Most inhaled anesthetics SE

Back 43

Decrease arterial blood pressure

Front 44

Inhaled anesthetics are myocardial depressants (2)

Back 44

Enflurane and halothane

Front 45

Inhaled anesthetic causes peripheral vasodilation

Back 45

Isoflurane

Front 46

Inhaled anesthetic that may sensitize the myocardium to arrhythmogenic effects of catecholamines and has produced hepatitis

Back 46

Halothane

Front 47

Inhaled anesthetic, less likely to lower blood pressure than other agents, and has the smallest effect on respiration

Back 47

Nitrous oxide

Front 48

Fluoride released by metabolism of this inhaled anesthetic may cause renal insufficiency

Back 48

Methoxyflurane

Front 49

Prolonged exposure to this inhaled anesthetic may lead to megaloblastic anemia

Back 49

Nitrous oxide

Front 50

Pungent inhaled anesthetic which leads to high incidence of coughing and vasospasm

Back 50

Desflurane

desflurane is desgusting