Pharm Oneliners Sets Of 50 Part 7

Front 1

Drug used for African sleeping sickness

Back 1

Suramin

Front 2

Drug used in Chagas disease

Back 2

Nifurtimox

Front 3

Cephalosporins NOT able to cross BBB

Back 3

Cefixime

Front 4

Cephalosporins able to cross the BBB

Back 4

Cefuroxime (2nd) generation, Ceftriaxone, and Ceftazidime

Front 5

Drug used for N. gonorrhea in females

Back 5

Ceftriaxone

Front 6

Cephalosporin causes kernicterus in neonates

Back 6

Ceftriaxone or cefuroxime

Front 7

SE of INH (2)

Back 7

Peripheral neuritis and hepatitis

Front 8

Aminoglycoside that is least ototoxic

Back 8

Streptomycin

Front 9

Drug used in exoerythrocytic cycle of malaria

Back 9

Primaquine

Front 10

Oral antibiotic of choice for moderate inflammatory acne

Back 10

Minocycline

Front 11

Drug of choice for leprosy (3)

Back 11

Dapsone, rifampin and clofazimine combination

Front 12

DOC for herpes and its MOA

Back 12

Acyclovir; incorporated into viral DNA and chain termination

Front 13

Anti-microbials that cause hemolysis in G6PD-deficient patients

Back 13

Sulfonamides

Front 14

MOA of erythromycin

Back 14

Inhibition of protein synthesis at the 50s subunit of ribosome

Front 15

Anti-biotic frequently used for chronic UTI prophylaxis

Back 15

sulfamethoxazole/ trimethoprim

Front 16

Lactam that can be used in PCN allergic patients

Back 16

Aztreonam

Front 17

SE of imipenem

Back 17

Seizures

Front 18

Anti-viral with a dose limiting toxicity of pancreatitis

Back 18

Didanosine

Front 19

Sedative Hypnotics

Front 20

Common side effect of hypnotic agents

Back 20

Sedation

Front 21

Occurs when sedative hypnotics are used chronically or at high doses

Back 21

Tolerance

Front 22

The most common type of drug interaction of sedative hypnotics with other depressant medications

Back 22

Additive CNS depression

Front 23

Benzodiazepines used to promote sleep (3)

Back 23

Temazpam, triazolam, flurazepam

Front 24

Benzodiazepine used for anxiety

Back 24

alprazolam (Ativan)

Front 25

Non-benzodiazepine used as an anxiolytic

Back 25

buspirone (Buspar)

Front 26

Non-benzodiazepine used for sleep

Back 26

Zolpidem

Front 27

Major effect of benzodiazepines on sleep at high doses

Back 27

REM is decreased

Front 28

Neurologic SE of benzodiazepines

Back 28

Anterograde amnesia

Front 29

Reason benzos are used cautiously in pregnancy

Back 29

Ability to cross the placenta

Front 30

Main route of metabolism for benzodiazepines

Back 30

Hepatic

Front 31

Benzodiazepines that undergo extrahepatic conjugation (which are useful in older or hepatically impaired) (3)

Back 31

Lorazepam, oxazepam, and temazepam

LOT

Front 32

MOA for benzodiazepines

Back 32

increase the FREQUENCY of GABA-mediated chloride ion channel opening

Front 33

Antidote to benzodiazepine overdose (antagonist that reverses the CNS effects)

Back 33

Flumazenil

Front 34

Benzodiazepine with useful relaxant effects in skeletal muscle spasticity of central origin

Back 34

Diazepam

Front 35

Benzodiazepine that has efficacy against absence seizures and in anxiety states, such as agoraphobia

Back 35

Clonazepam

Front 36

Benzodiazepines that are the most effective in the treatment of panic disorder

Back 36

Alprazolam and Clonazepam

Front 37

Benzodiazepine that is used for anesthesia

Back 37

Midazolam

Front 38

DOC for status epilepticus

Back 38

diazepam (Valium)

Front 39

Longer acting benzodiazepines used in the management of withdrawal states of alcohol and other drugs

Back 39

Chlordiazepoxide (Librium) and Diazepam (Valium)

Front 40

Benzodiazepines having active metabolites, long half lives, and a high incidence of adverse effects (4)

Back 40

diazepam (Valium), Flurazepam, chlordiazepoxide (Librium), and clorazepate

Front 41

Barbiturates

Front 42

Barbiturates may precipitate this hematologic condition

Back 42

Acute intermittent porphyria

Front 43

Barbiturates decrease the effectiveness of many other drugs via this pharmacokinetics property

Back 43

Liver enzyme INDUCTION

Front 44

Barbiturates MOA

Back 44

Increase the DURATION of GABA-mediated chloride ion channels

Front 45

Barbiturate used for the induction of anesthesia

Back 45

Thiopental

Front 46

Others

Front 47

Site of action for zaleplon and zolpidem

Back 47

Benzodiazepine receptor BZ1 (although do not have a benzodiazepine ring structure)

Front 48

Good hypnotic activity with less CNS SE than most benzodiazepines (2)

Back 48

zolpidem (Ambien), zaleplon (Sonata)

Front 49

Agent that is a partial agonist for the 5-HT1A receptor

Back 49

Buspirone

Front 50

Drug of choice for generalized anxiety disorder, NOT effective in acute anxiety

Back 50

Buspirone