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50 Cards in this Set
- Front
- Back
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Primary endogenous substrate for Nitric Oxidase Synthase
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Arginine
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MOA and effect of nitric oxide
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Stimulates cGMP which leads to vascular smooth muscle relaxation
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Long acting beta 2 agonist used in asthma
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Salmeterol
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Muscarinic antagonist used in asthma
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Ipratropium
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MOA action of cromolyn
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Mast cell stabilizer
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Methylxanthine derivative used as a remedy for intermittent claudication
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Pentoxifylline
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MOA of corticosteroids
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inhibit phospholipase A2
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SE of long term (>5 days) corticosteroid therapy and remedy
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Adrenal suppression and weaning slowly, respectively
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Antimicrobials
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MOA of quinolones
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Inhibit DNA gyrase
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MOA of penicillin
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Block cell wall synthesis by inhibiting peptidoglycan cross-linkage
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Drug used for MRSA
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Vancomycin
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Vancomycin MOA
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Blocks peptidoglycan synthesis
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Type of resistance found with vancomycin
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Point mutation
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Meningitis prophylaxis in exposed patients
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Rifampin
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Technique used to diagnose perianal itching, and the drug used to treat it
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Scotch tape technique and mebendazole
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Two toxicities of aminoglycosides
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nephro and ototoxicity
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DOC for Legionnaires' disease
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Erythromycin
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MOA of sulfonamides
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Inhibit dihydropteroate synthase
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Penicillins active against penicillinase secreting bacteria
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Methicillin, nafcillin, and dicloxacillin
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Cheap wide spectrum antibiotic DOC for otitis media
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Amoxicillin
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Class of antibiotics that have 10% cross sensitivity with penicillins
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Cephalosporins
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PCN active against pseudomonas
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Carbenicillin, piperacillin and ticarcillin
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Antibiotic causing red-man syndrome, and prevention
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Vancomycin, infusion at a slow rate and antihistamines
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Drug causes teeth discoloration
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Tetracycline
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MOA of tetracycline
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Decreases protein synthesis by inhibiting 30S ribosome
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Drug that causes gray baby syndrome and aplastic anemia
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Chloramphenicol
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Drug notorious for causing pseudomembranous colitis
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Clindamycin
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DOC for tx of pseudomembranous colitis
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Metronidazole
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Treatment of resistant pseudomembranous colitis
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ORAL vancomycin
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Anemia caused by trimethoprim
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Megaloblastic anemia
[TMP inhibits dihydrofolate reductase --> defect in folate metabolism --> megaloblastic anemia] |
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Reason fluoroquinolones are contraindicated in children and pregnancy
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Cartilage damage
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DOC for giardia, bacterial vaginosis, pseudomembranous colitis, and trichomonas
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Metronidazole
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Treatment for TB patients (think RIPE)
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Rifampin, Isoniazid, Pyrazinamide, and Ethambutol
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Metronidazole SE if given with alcohol
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Disulfiram-like reaction
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Common side effect of Rifampin
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Red urine discoloration
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MOA of nystatin
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Bind ergosterol in fungal cell membrane
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Neurotoxicity with isoniazid (INH) prevented by
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Administration of Vit. B6 (pyridoxine)
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Toxicity of amphotericin
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Nephrotoxicity
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SE seen only in men with administration of ketoconazole
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Gynecomastia
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Topical DOC in impetigo
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Topical mupirocin (Bactroban)
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DOC for influenza A
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Amantadine
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DOC for RSV
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Ribavirin
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DOC for CMV retinitis
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Ganciclovir
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SE for ganciclovir (3)
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Neutro, leuko and thrombocytopenia
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Anti-viral agents associated with Stephen Johnson syndrome (2)
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Nevirapine, amprenavir
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HIV antiviral class known to have severe drug interactions by causing inhibition of metabolism
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Protease inhibitors
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Antivirals that are teratogens
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ribavirin, efavirenz, and delavirdine
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Antivirals associated with neutropenia (4)
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Ganciclovir, zidovudine (AZT), saquinavir, and interferon
Sucks that I Got Zero neutrophils |
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HIV med used to reduce transmission during birth
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AZT (zidovudine)
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