Pharm Oneliners Sets Of 50 Part 3

Front 1

GnRH agonist used for infertility or different types of CA depending on pulsatile or steady usage respectively

Back 1

Leuprolide

Front 2

GnRH antagonist with more immediate effects, used for infertility

Back 2

Ganirelix

Front 3

Dopamine (DA) agonist (for Parkinson's disease), used also for hyperprolactinemia

Back 3

Bromocriptine

Front 4

Hormone inhibiting prolactin release

Back 4

Dopamine

Front 5

ACTH analog used for diagnosis of patients with corticosteroid abnormality

Back 5

Cosyntropin

for an ACTHual diagnosis you must Co-Sign the form.

Front 6

Synthetic analog of ADH hormone used for diabetes insipidus and nocturnal enuresis

Back 6

Desmopressin (DDAVP)

Front 7

SE of OCPs

Back 7

Increased thromboembolic events

Front 8

Thyroid and anti-thyroid drugs

Front 9

Most widely used thyroid drugs such as Synthroid and Levoxyl contain

Back 9

L-thyroxine (T4)

Front 10

T3 compound less widely used

Back 10

Cytomel (liothyronine)

Front 11

Anti-thyroid drugs (4)

Back 11

Thioamides, iodides, radioactive iodine, and ipodate

Front 12

Thioamide agents used in hyperthyroidism

Back 12

Methimazole and propylthiouracil (PTU)

Front 13

Thioamide less likely to cross placenta, inhibits peripheral conversion of T4 to T3 in high doses, and should be used with extreme caution in pregnancy

Back 13

PTU

Front 14

PTU (propylthiouracil) MOA

Back 14

Inhibits thyroid hormone synthesis by blocking iodination of the tyrosine residues of thyroglobulin

Front 15

Can be effective for short term therapy of thyroid storm, but after several weeks of therapy causes an exacerbation of hyperthyroidism

Back 15

Iodide salts

Front 16

Dose may need to be increased during pregnancy or with Ocs due to increased TBG in plasma

Back 16

Thyroxine

Front 17

Permanently cures thyrotoxicosis, patients will need thyroid replacement therapy thereafter. Contraindicated in pregnancy

Back 17

Radioactive iodine

Front 18

Radio contrast media that inhibits the conversion of T4 to T3

Back 18

Ipodate

Front 19

Block cardiac adverse effects of thyrotoxicosis such as tachycardia, inhibits the conversion of T4 to T3

Back 19

Beta-blockers such as propranolol

Front 20

Vitamins containing iron should NOT be taken simultaneously with levothyroxine because

Back 20

Iron deiodinates thyroxine

Front 21

Thyroxine dose may need to be increased in hypothyroid patient during pregnancy because

Back 21

Estogens increase maternal TBG

Front 22

Adrenocorticosteroid and adrenocortical antagonists

Front 23

3 zones of adrenal cortex and their products

Back 23

Glomerulosa (mineralocorticoids), fasciculata (glucocorticoid=GC), and reticularis (adrenal androgens)

Front 24

Pneumonic for 3 zones of adrenal cortex

Back 24

GFR

Front 25

Agents used for Addison's disease, Congenital Adrenal Hyperplasia (CAH), inflammation, allergies, and asthma (as a local inhalation)

Back 25

Glucocorticoids

Front 26

Short acting glucocorticoids

Back 26

Cortisone and hydrocortisone (equivalent to cortisol)

Front 27

Intermediate acting glucocorticoids

Back 27

Prednisone, methylprednisolone, prednisolone, and triamcinolone

Front 28

Long acting glucocorticoids

Back 28

Betamethasone and dexamethasone

Front 29

Mineralocorticoids (2)

Back 29

Fludrocortisone and deoxycorticosterone

Front 30

Some side effects of corticosteroids (11)

Back 30

Osteopenia, impaired wound healing, stria, thinning of skin,
increased appetite, PUD, HTN, edema,
increased risk of infection,
euphoria, psychosis

Front 31

Period of time of therapy after which GC therapy will need to be tapered

Back 31

5-7 days

Front 32

Inhibitors of corticosteroids biosynthesis

Front 33

Used for Cushing's syndrome (increased corticosteroid)

Back 33

Dexamethasone suppression test

Front 34

Inhibits conversion of cholesterol to pregnenolone therefore inhibiting corticosteroid synthesis

Back 34

Aminoglutethimide

Front 35

Antifungal agent used for inhibition of all gonadal and adrenal steroids

Back 35

Ketoconazole

Front 36

Antiprogestin used as potent antagonist of GC receptor

Back 36

Mifepristone

Front 37

Diuretic used to antagonize aldosterone receptors

Back 37

Spironolactone

Front 38

Common SE of spironolactone

Back 38

Gynecomastia and hyperkalemia

Front 39

Gonadal hormones and inhibitors

Front 40

Slightly increased risk of breast cancer, endometrial cancer, heart disease (questionable), has beneficial effects on bone loss

Back 40

Estrogen

Front 41

Antiestrogen drugs used for fertility and breast cancer respectively

Back 41

Clomiphene and tamoxifen

Front 42

Common SE of tamoxifen and raloxifene

Back 42

Hot flashes

Boob meds give hot flashes

Front 43

Selective estrogen receptor modulator (SERM) used for prevention of osteoporosis and prophylaxis in women with risk factors for breast cancer

Back 43

Raloxifene

Front 44

Non-steroidal estrogen agonist causes clear cell adenocarcinoma of the vagina in daughters of women who used it during pregnancy

Back 44

Diethylstilbestrol (DES)

Front 45

Estrogen mostly used in oral contraceptives (OC) (2)

Back 45

Ethinyl estradiol and mestranol

Front 46

Anti-progesterone used as abortifacient

Back 46

Mifepristone (RU-486)

Front 47

Constant low dose of estrogen and increasing dose of progestin for 21 days (last 5 days are sugar pills or iron prep)

Back 47

Combination oral contraceptives (OC)

Front 48

Oral contraceptive available in a transdermal patch

Back 48

Ortho-Evra

Front 49

Converted to more active form DHT by 5 alpha-reductase

Back 49

Testosterone

Front 50

5 alpha-reductase inhibitor used for benign prostatic hyperplasia (BPH) and male pattern baldness

Back 50

Finasteride (Proscar and Propecia respectively)