Pharm One Liners- Skeletal Muscle Relaxants

Front 1

Structurally related to acetylcholine, used to produce muscle paralysis in order to facilitate surgery or artificial ventilation. Full doses lead to respiratory paralysis and require ventialtion

Back 1

Neuromuscular blocking drugs

Front 2

These drugs strongly potentiate and prolong effect of neuromuscular blockade

Back 2

Inhaled anesthetics, isoflurane, AG, and antiarrhythmic

Front 3

These prevent the action of Ach at the skeletal muscle endplate to produce a surmountable blockade effect is reversed by cholinesterase inhibitors (ex. neostigmine or pyridostigmine)

Back 3

Nondepolarizing type of antagonist

Front 4

Agent with long duration of action and is most likely to cause histamine release

Back 4

Tubocurarine

Front 5

Non-depolarizing antagonist has short duration

Back 5

Mivacurium

Front 6

Agent can block muscarinic receptors

Back 6

Pnacuronium

Front 7

Agent undergoing Hofmann elimination breaking down spontaneously

Back 7

Atracurium

Front 8

One depolarizing blocker that causes continous depolarizing and results in muscle relaxation and paralysis. xcuses muscle pain postoperatively and myoglobinuria may occur

Back 8

Succinylcholine

Front 9

During Phase I these agents worsen the paralysis by succinylcholine, but during phase II they reverse the blockade produced by succinylcholine

Back 9

Cholinesterase inhibitors