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9 Cards in this Set
- Front
- Back
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For which medical condition are barbiturates contraindicated?
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Porphyria
[ The barbiturates induce drug-metabolizing enzymes, including the P450 system, leading to potential drug interactions. They also stimulate heme synthesis and are contraindicated in porphyrias. ] |
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Which class of drug is used to treat Delirium Tremens?
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Benzodiazepines
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What is the mechanism of action of Buspirone?
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Stimulates 5-HT(1A) receptors.
Used for generalized anxiety disorders. Does not cause sedation, addiction, or tolerance. Does not interact with alcohol (vs. barbiturates, benzodiazepines). |
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What is the most common cause of death is opioid overdose?
What two side effects does tolerance NOT to in opioid addiction? |
Respiratory depression is the most common cause of death in acute opioid overdose.
Tolerance does not develop to miosis and constipation. |
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Which neurotransmitters are increased or decreased in Parkinson's?
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Decreased Dopamine.
Increased ACh |
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What is the drug of choice for the treatment of trigeminal neuralgia?
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Carbamazepine
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Which antidepressant drug should be avoided in bulimic patients, and which side effect is the primary concern?
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BUPROPION can cause seizures in bulimic patients.
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DANTROLENE?
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Mechanism: Prevents the release of Ca from the sarcoplasmic reticulum of skeletal muscle
Clinical Uses: Used in the treatment of MALIGNANT HYPERTHERMIA, which is caused by the concomitant use of inhalation anesthetics (except N2O) and succinylcholine. Also used to treat NEUROLEPTIC MALIGNANT SYNDROME (a toxicity of antipsychotic drugs) |
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Which neurotransmitters are altered in Parkinson's?
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Dopamine is decreased.
ACh is increased. |
