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33 Cards in this Set

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additive
2 drugs whoses sum effect when given togethere is = to the effect form each given seperately but at the same time
agonist
drug that activates its receptors upon binding
(activation)
antagonist
drug that binds to receptor without activiting it
(no activiation)
bioavailablity
fraction of drug that reaches the systemi circulation
dependence
drug with withdrawl symptoms on discontinuation. Physiological or psychological
desensitization
loss of tissue responsiveness that can occure with drug exposure
disease mngmt
all inclusive mngmnt of a patients diesease
enteral route
oral, sublingual,nasogastric, rectal routes of drug absorption
first pass effect
elimination of drug after administration but before it reaches the systemic circulation
formulary
list of drugs stocked by pharm
half life
time it takes for the drug concentration to fall to 50% in the body
loading dose
dose that is first administered to rapidly achieve a therapeutic concentration
maintenance dose
dose given to keep a drug at a therapeutic level in the blood
parenteral route
injectable bypass the alimentary tract
pharmacodynamics
action drug on body
pharmacokinetics
action body on drug
pharmacology
study of drug and action on the body
pharmacotherapy
application of drug therapy to disease treatment
potentiation
the effect of 2 drugs given together when 1 drug has no effect but increases the response of the other drug, which normally has a lesser effect
protein binding
refers to sites such as albumin where the drug is connected or bount and inactive, influences drug dist.
racemic
refers to drugs that contain 2 chemical components that may have different activity
receptor
targets for drugs to act on
selectivity
drug reacts on one specific site or receptor
steady state
state reached when input of the drug is equal to the output of drug over the dosing interval
sublingual
drug absorption under tongue
synergism
two drugs given together, effect is greater than if given seperately
teratogenic
effect on prenatal dev. that results in abnormal structure or function
therapeutic index
quantitive measure of drugs safety
therapeutic range
range of drug concentration in the body in which the drug produces the desired response
therapeutics
study of drugs used to cure, treat, or prevent diesease
tolerance
decrease in susceptibility to a drugs effect from continued use
toxicology
study of drug as it relates to poisioning and enviromental toxins
transdermal
deliverd thru skin