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9 Cards in this Set

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general properties of all Aminoglycosides
effective against: PEPSN
Pseudomonas, Enterobacter, Proteus, Serratia, Nisseria

Typically used for severe systemic infections
rapid Kidney excretion
Resistance is plasmid mediated

Mean GNATSS P can NOT kill anaerobes
SE:
"NOT"

Nephrotoxic, Ototoxic, NMJ toxicity, teratogenic
Streptomycin
Tx: tularemia, bubonic plaque, tuberculosis, endocarditis
Neomycin
Tx: pre-op prophylaxis for colon surg, hepatic encephalopathy
not absorbed in the GI so it kills GI bac, lowers ammonia concentration, and prevents hepatic encephalopathy
Paromomycin
Tx: intestinal amebiasis, Cryptosporidium, tapeworm
Neomycin and gentamicin
topical for wounds and burns
General properties of Tetracyclines
Broad spec: VACcUMe THe BedRooMS
Vibrio, Acne, Chlamydia, Uroplasma, Mycoplasma, Tularemia, H. Pylori, Borriella, Rickettsia, Malaria, Shigella

Chelated by Ca++, Fe++, Al+++. in the gut

excreted by Kidneys
SE: Overgrowth of Candidia
teeth discoloration
Stunted Bone growth
Fanconi synd - renal tubular acidosis
Long acting tetracyclines
Doxy & Mino
Short acting tetracyclines
tetracycline
Tigecycline
a Glycylcycline derived from Minocycline

"tetracyclines on steroids"
Tx: MRSA, MRSE, PRSP, VRE