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34 Cards in this Set
- Front
- Back
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acyclovir has a ___ base and is phosphorylated by __....eventually resulting in ___
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guanine
thymidine kinase chain termination |
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list one non-nucleoside RT inh
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Efavirenz
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list 3 protease inhibitors used in AIDS Tx
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darunavir
lopinavir ritonavir |
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an integrase inhibitor used in AIDS Tx
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raltegravir
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list one fusion inhibitor that binds to gp120 and prevents virus from attaching to CD4 cells
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enfuvirtide
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issue w/ enfuvirtide
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HIV virus has CXR4 receptor that can be used for fusion
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drug that has photosenstivity side effect
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tetracycline
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drug that has suicide association....used for smoker withdrawal
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verenicline (chantix)
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when taking ACE inhibitors you can get a buildup of ____ leading to a cough
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bradykinin
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these drugs reduce hepatic blood flow
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beta blockers
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which drugs block pseudocholinesterase
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neostigmine, physostigmine
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tetracyclines interact w/
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antacids
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you mix these 2 drugs in the patient
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aminoglycosides and beta lactams
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list one drug that stimulates p450
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rifampin
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what drug causes intrinsic staining of teeth
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tetracycline
ciprofloxacin |
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drug that is an alpha agonist and causes decreased AcH release
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clonidine
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this drug might cause the sublingual gland to hypertrophy
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prazosin
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drugs causing extrinsic stain
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CHX
liquid Fe amox |
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drugs causing tooth erosion
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anti-cancer drugs
Ca channel blockers inhaled steriods |
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virus structure
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protein coat (capsid)
lipoprotein envelope |
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insect vector
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arbovirus
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list 4 drugs for influenza virus
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amantadine
rimantadine oseltamivir zanamivir |
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list 2 neuraminadase inhibitors
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oseltamivir
zanamivir |
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tell me about tetracyclines
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inh protein synth
static excreted through feces NOT kidney |
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cations w/ tetracyclines
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Ca
Fe Al Mg |
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tetracyclines chelates in ___....which implicates what?
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chelates in GI leading to poor absorption....so do take tetracyclines with the above cation supplements
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list the uses of tetracyclines
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mycoplasma
rickettsia (rocky mtn sp. fvr) lyme disease chlamydia cholera brucella helicobacter |
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4 Tx for helicobacter
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tetracycline
macrolides metronidazole bismuth subsalicylate |
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tell me about chloramphenicol
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used for RMSfever
pancytopenia toxic gray baby syndrome (can't glucuronidate drug) |
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4 toxicities of fluoroquinolones
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1. arthropathy
2. tendonitis 3. cardiac arrest - QT interval 4. seizures |
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uses of fluoroquinolones
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g+/g-
RMSfvr CHRONIC UTIs serious bone or resp. infections (CF) |
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neosporin
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bacitracin (g+)
neomycin (g-) polymixin B (g-) |
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topical antibiotic used for eye infection
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sulfacetamide
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fluoroquinolones are metabolized in ___ and eliminated in ____
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metabolized in liver
elim in kidney |
