Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
23 Cards in this Set
- Front
- Back
|
prednisone
|
corticosteroid effects transcription of arachidonic producers
|
|
|
prenisolone
|
corticosteroid, effects transcription of arachidonic producers
|
|
|
cyclosporine
|
immunosuppressant, inhibits interleukin 2 transcription, inhibits T cell activation
|
|
|
tacrolimus (F506)
|
immunosuppressant, 100Xs more potent than cyclosporine, inhibits interleukin 2 transcription, inhibits T cell activation
|
|
|
sirolimus
|
immunosuppressant, inhibits T cell activation and T cell proliferation
|
|
|
azathioprine
|
cytotoxic, purine antimetabolite, competitive inhibitor of inosinic acid, blocks T cell proliferation more than B cell, arrests them in DNA synthesis protion of cell cycle
|
|
|
mycophenolate
|
cytotoxic, inhibition of inosine monophosphate dehydrogenase, blocks B and T cell proliferation
|
|
|
cyclophosphamide
|
cytotoxic, alkylating agent
|
|
|
methotrexate
|
cytotoxic, anti-metabolite
|
|
|
FTY720
|
sphingosine 1-phosphate receptor agonist (SIP-R), sequesters lymphocytes in lymph node and peyer's patch. protects grafts from T cell mediated attack.
|
|
|
antithymocyte globulin (ATG)
|
antibody, purified immunoglobin from horses, removes T cells from blood, spleen, and lymph nodes
|
|
|
immune globin
|
antibody, human plasma from hyperimmunized donors
|
|
|
orthoclone OKT3
|
antibody, mouse monoclonal antibody, binds CD3 and blocks antigen recognition complex on T cells, T cells unable to recognize foreign antigen
|
|
|
basiliximab
|
antibody, mouse/human, anti-IL2, blocks receptor on T cells
|
|
|
daclizumab
|
antibody, mouse/human, anti-IL2, blocks receptor on T cells
|
|
|
infliximab
|
antibody, binds TNF alpha receptor on T cells
|
|
|
etanercept
|
antibody, binds TNF alpha receptor on T cells
|
|
|
Rh o (D) immune globin (Rhogan)
|
antibody, anti-D or Rh, block antibody responxe of Rh negative mother to a Rh positive baby
|
|
|
bacillus calmette-guerin (BCG)
|
immunostimulant, viable attenuated strain of myobacterium bovis, T cells and natural killers stimulated
|
|
|
thymic factor
|
immunostimulant, promote T cell and early stem cells differentiation
|
|
|
interleukin 2
|
immunostimulant, promotes prolif, differentiation, and recruitment of T and B cells, natural killers, and thymocytes
|
|
|
granulocyte macrophage colony stimulating factor (GM-CSF)
|
immunostimulant, cytokines that stimulate the clonal expansion and differentiation of granulocytes and macrophages
|
|
|
granulocyte colony stimulating factor (G-CSF)
|
immunostimulant, cytokines that stimulate the clonal expansion and differentiation of granulocytes
|
