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35 Cards in this Set
- Front
- Back
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Affect Cell Wall (4*)
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Beta lactams
Bacitracin Vancomycin Cycloserine [Novobiocin: affects cell wall, protein synthesis, nucleic acid synthesis] "Big Bad Velociraptors Can fly over walls" |
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Affect Cell Membrane (2)
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Polymyxin B
Colistin |
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Affect Protein Synthesis (6)
- at 23S ribosomal subunit (1) - at 30S ribosomal subunit (2) - at 50S ribosomal subunit (3) |
Virginiamycin (23S)
Tetracyclines (30S) Aminoglycosides (30S) Chloramphenicol & derivs (50S) Macrolides (50S) Lincomycin (50S) "V<AT<CML -- 23S<30S<50S" |
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Affect Bacterial Nucleic Acid (3)
- DNA or RNA? |
Fluoroquinolones (inhibit DNA replication)
Metronidazole (inhibit DNA replication) Rifampin (inhibit RNA synthesis) |
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Broad Spectrum (10)
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Sulfonamides
Rifampin Fluoroquinolones Chloramphenicol & derivs Macrolides Tetracyclines Amoxicillin Ampicillin Carbapenems Methenamine "SuRF CMT" for the main groups |
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Narrow spectrum (3)
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Beta-lactams
Aminoglycosides Polymyxin & Colistin "Ball CAP" |
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Bacteriostatic (5*)
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Tetracyclines
Chloamphenicol & derivs Macrolides & lincomycin Sulfonamides Diaminopyrimidines [Methenamine depends on pH] "MaD CaTS are static" |
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Bactericidal (6)
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Beta-lactams
Aminoglycosides Fluoroquinolones Metronidazole Polymyxin & Colistin Vancomycin "Very Pugnacious BAMFs will kill you" |
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Synergistic (5)
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- Penicillin/cephalosponrin & aminoglycosides
- Sulphonamide w. trimethoprim - Clavulanic acid w. beta lactam - colistin w. trimethoprim-sulfa - polymixins w. chlorahexadine (for pseudomonas) |
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Interfere with folic acid (2)
- Inhibit what enzyme? |
Sulfonamides - dihydropteroate Synthase
Diaminopyrimides - dihydrofolate reDuctase |
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Diaminopyrimidines (3)
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Ormetroprim
Pyrimethamine Trimethoprim |
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Pseudomonas (8)
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Carbapenems
Cefepime (gen 4) Extended spectrum Monobactams Tilmicosin Fluoroquinolones Polymyxin B & colistin Polymyxin and Chlorhexidine "Pseudomonas Croaked at Country Music F(ES)T" |
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Topical (5)
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Silver Sulfadiazine & Mafenide
Theostrepton Bacitracin Nitrofurans Polymyxin |
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Opthalmic Uses (4)
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Sulfacetamine
Cloxacillin Chloramphenicol Bacitracin "Crazy Bat Can't See" |
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Otic (2)
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Chloramphenicol
Bacitracin |
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Type I (3)
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CONCENTRATION DEPENDENT KILLING KINETIC
Aminoglycosides Fluoroquinolones Metronidazole "FAMily first" |
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Type II (6)
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TIME DEPENDENT KILLING KINETIC
Sulfonamide Cephalosporin Penicillins Chloramphenicol + derivs Macrolides Lincosamides "aCCoMPLiceS second" |
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Type III (2)
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TIME DEPENDENT KILLING KINETIC w/ PAE (post-antibiotic effect)
Tetracycline Azythromycin |
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Renal Excretion (14)
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Sulfonamide
Diaminopyrimidines Potentiated S&D Penicillin Aminoglycosides Tetracycline (60%) Chloramphenicol Thiamphenicol Florenical Clanthromycin & bile Tilmicosin & bile Fluoroquinolone & bile Metronidazole Methenamine |
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Fecal Excretion (4)
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Enteric sulfonamide
Tetracycline (40%) Doxycycline Difloxacin "do TEDDy bears shit in the woods?" |
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Bile excretion (11)
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Chloramphenicol
Doxycycline Nafcillin Ceftriaxone Cefoperazone Erythromycin and urine Azithromycin Tylosin Lincosamides and urine Virginiamycin Rifampin "C3DN Excreted AT LiVeR" |
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Liver Metabolism (11)
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Chloramphenicol
Diaminopyrimides Sulfonamide Potentiated S&D Cephalosporin Minocycline Erythromycin Clindamycin Fluorquinolones Metronidazole Rifampin (& kidney) |
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Gram + (8)
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Beta lactams
Ceftiofur Gentamicin (some) Erythromycin Lincomycin Bacitracin Virginiamycin Carbadox "Big VEGan Cows BeLCh" (+ bc it's a true statement) |
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Gram – (9)
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Extended spectrum penicillins
Cefazolin (best) 2nd gen. cephalos. 3rd gen. cephalos (most effective of group) Carbapenems Monobactams Aminoglycosides (amikacin is best) Clindamycin Polymyxin B |
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Gram +/- (13)
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Sulfonamides
Potentiated S&D Natural Penicillins Cephalosporins Paramomycin Tetracycline Chloramphenicol Tilmicosin Fluoroquinolones Methenamine Nitrofurans Thiosterpton Novobiocin |
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Aerobic (5)
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Sulfonamide
Extended spectrum Aminoglycosides Tetracyclines Chloramphenicol |
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Anaerobic (8)
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Natural penicillin
Extended spectrum Cephamycin group Ceftiofur Carbapenems Tetracyclines Chloramphenicol Metronidazole |
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Enteric Sulfonamides (5)
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Sulfasalazine
Sulfaquinoxaline Sulfaguanidine Phthalylsulfathiazole Succinylsulfathiazole |
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Beta Lactamase inhibitors (2)
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Clavulanic Acid
Sulbactam |
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Aminoglycosides (6)
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Streptomycin
Neomycin Kanamycin Gentamycin Amikacin Tobramycin "Kill GNATS" |
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Common Tetracyclines (5)
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Chlortetracycline
Tettracycline Oxytetracycline Minocycline Doxycycline |
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Macrolides (6)
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Erythromycin
Tilmicosin Tylosin Tiamulin Azithromycin Clarithormycin |
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No Use In Food Animals (5)
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Nitrofurans
Vancomycin Metronidazole Chloramphenicol Furazolidone "Never Feed Me Contaminated Veal" |
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Protozoa (9)
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Sulfonamides
Pyrimethamine Sulfonamide Poten. Paramomycin Tetracycline Clindamycin Metronidazole Nitrofurans Virginiamycin "People CaN Meet Very Small ProTozoa" |
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C-P450 Metabolism (3)
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Macrolides (inhibits enzyme)
Metronidazole Rifampin (induces enzyme) |
