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58 Cards in this Set
- Front
- Back
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hCG is similar to what endogenous hormone?
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LH
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eCG is similar to what endogenous hormone?
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FSH
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What combination of hormones stimulates estrus in puberal gilts?
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FSH and hCG
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What hormone combination causes superovulation of cattle?
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eCG and PGF2alpha
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Deslorelin Acetate
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Use specifically in mares to induce ovulation
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Mibolerone is used primariy for?
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Tretment of psuedopregnancy of bitches
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What hormone is used as a growth promoter in cattle
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Skin implantation of androgens (testosterone-estrodiol or trenbolone)
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Trenbolone is use for?
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Growth promotion in cattle
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Boldenone is use in what species?
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horses
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Stanzolol and bolderonoe are used primarily for what?
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Chronic wasting diseases and as appitie stimulants.
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What are the estradiol esters?
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CPBV - Cypionate, Propionate, Benzoate, Valerate
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what is the clinical use for Zeranol?
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Growth prmoter in sheep (and cattle)
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Progestin and estrodiol valate are used for what?
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synchronization of cattle
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Why don't we use estrogens in mismating?
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It causes pyometra
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nidation
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Implantation of embryo
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Estrogens are good for prostate neoplasia, hyperplasia of the prostate and anal gland adenomas for what reason?
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Due to the negative feedback it provides for testosterone so you get a lower level of androgen in the bloodstream
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Estrogen will to what to estrus?
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Induce it without ovulation
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Oh estrogen and progesterone, which one causes uterine prolapse?
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Estrogens
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what are the adverse effects of estrogen use?
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Aplastic anemia and leukopenia (due to bm suppression) Pyometra (with mismating), femininization of males, follicular cysts,
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What species - Megestrol acetate
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Dogs
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What species - Hydroxyprogesterone caproate
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Cats
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What species - Altrenogest
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Mares
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What species - Norgestomet
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Implants use in beef cattle and non-lactating dairy cows
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What species - Melengestrol acetate
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Used in cattle feed
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what are progestins used for in large animals?
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Supression of estrus (synchronization) and a growth promoter
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What is altrenogest used for?
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Used in mares to avoid premature labor
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For spray and behavior problems in cats, what 2 hormones would you use?
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Dihydroxyprogesterone caproate and medroxyprogesterone acetate
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what is the main function of PGF2alpha?
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To stimulate contraction of the reproductive tract in both males and females
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what 2 PGF2alpha synthetic agents are used in cattle?
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Cloprestenol and Fenprostalene
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PGF2alpha is the DOC for?
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mummified fetus expulsion or placental expulsion in cattle
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what are the clinical uses for PGF2alpha?
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Abortifactant, DOC for expulsion of mummified fetus and placenta, destroying CL (causing synchronization) Tx of silent estrus in cattle and used to reduce post-partum bleeding
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What do we use PGF2alpha for in small animals
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Not approved/dangerous but can be used in mismating and the TX uterine infections
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what are the side effects of PGF2alpha?
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savilation, anxiety, pyrexia, hyperpnea, ataxia
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what drug can we use to reduce side effects of PGF2alpha?
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Atropine
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What is the main function of uterine stimulants?
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Causes contraction of uterus and indirect vasoconstriction
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what are the clinical uses of uterine stimulants?
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Antinidatory, abortificaient, stimulates oxytocin, also used for post-partum bleeding
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What are examples of uterine stimulants?
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PGF2alpha, estrogens, oxytocin, Ergonovine and prolactin inhibitors (such as dopamine)
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Ergoline derivatives
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Bromocriptine and cabergoline.
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what is the MOA of ergoline derivities
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Inhibits prolactin which inhibits CL when will inhibit progesterone secretion therefore you get no prgnancy. CL is integral to prgnancy
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dopamine antagonists (and therefore increase prolactin) and therefore don't antagonize pregnancy
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Metoclopramide, phenothiazine derivitives, and butorphinol
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Increased levels of prolactin in a non pregnant bitch causes what?
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Psuedopregnancy
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to induce abortion in cows (up to 150 days)
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Clonprostenol, dinoprost, or fenprostalene
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During the last month of gestation, to induce parturition use?
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Dexamethasone alone or PGF2alpha alone
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to cause abortion in cows from months 5-8 use?
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Dexamethasone and PGF2alpha
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DOC for induction of parturition in cows
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Dexamethasone
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DOC for induction of parturition in mares
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Oxytocin
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DOC for induced parturition of dogs
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Oxytocin
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DOC of induced partutrition in sows
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PGF2alpha, followed by oxytocin
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DOC of fetus (mummified) or placenta
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PGF2alpha (ergovine, bromocriptine
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what is a tocolytic
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Drugs that inihbits uterine contraction
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Example of tocolytics
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Ritodrine, or terbutaline
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When are dopamine antagonists used?
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In cases of agalactia (due to increase of prolactin) or in fescue poisoning
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What is finasteride?
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It inhibits 5-alpha in reductase in prostate therefore reducing testosterone and reducing issues with a hypertrophic prostate.
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What is calcium gluconate used for?
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after it is neutralized by arginine - Chemical castration of puppies 3-10 months old
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What class fo drugs do we use for chemical ejaculation in stallions?
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TCA - tricyclic antidepressants
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what drug do we use for chemical ejaculation in stallions?
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Imiprimine
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What doe we use somatotropins for in large animals?
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Growth promotion and increased milk production
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What do we use somatotropins for in small animals?
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Treatment for dwarfism
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