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14 Cards in this Set
- Front
- Back
constriction of blood vessels, inhibits insulin secretion
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alpha 1
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inhibition of NE release (presynaptically in the periphery)
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alpha 2
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increased HR, contractility, conductance
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beta 1
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dilation of BVs, bronchioles, glycogenolysis, gluconeogenesis, insulin secretion, uterine relaxation
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beta 2
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enhancement of lipolysis in adipose tissue
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beta 3
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dilation of blood vessels
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DA1
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inhibition of NE release (negative feedback)
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DA2
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Pure alpha agonists
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phenylephrine and methoxamine
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Pure beta agonists
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dobutamine, isoproterenol
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Alpha > beta agonists
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norepinephrine
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Alpha = beta
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Ephedrine (direct and indirect effects), dopamine (dose dependent, 10 - 20 mcg/kg/min)
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Beta > alpha
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epinephrine, dopamine (dose dependent = 3 - 10 mcg/kg/min, B2, = B1)
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DA1 agonist
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Dopamine infusion @ < 3 mcg/kg/min = renal, mesenteric, and coronary vasodilation --> renal blood flow, sodium excretion, GFR, and UOP
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Dopamine infusion > 20 mcg/kg/min
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stimulates primarily alpha 1 receptors
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