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5 Cards in this Set
- Front
- Back
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What are the bile acid resins? (2)
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Cholestyramine
Colesevelam |
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What is one of the mechanisms of action of bile acid resins?
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Binds bile acids in the GI tract
DO NOT enter systemic circ (+) bile acid excretion (-) bile acid hepatic recirculation |
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What is one of the mechanisms of action of bile acid resins?
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Enhances hepatic conversion of cholesterol to bile acids
cholestero---> 7a hydroxylase --> cholic acid |
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What is one of the mechanisms of action of bile acid resins?
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Increases # of hepatic LDL recpetors
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Therapeutic uses of bile acids
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1. Hypercholesterolemia
2. peak effect at 4 wks 3. Ineffective for hypertriglyceridemia |
