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55 Cards in this Set

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antidote for:

salicylates (2)
alkalinze urine with bicarbonate (ionized salicylate becomes trapped in renal tubule)

dialysis
antidote for:

anticholinergic agents
physostigmine
antidote for:

β-blockers
glucagon
antidote for:

digitalis (4)
lidocaine
anti-dig Fab fragments
normalize K+
Mg2+
antidote for:

lead (3)
CaEDTA (low lead level)
dimercaprol (high lead level)
succimer (high lead level)
antidote for:

arsenic (3)
dimercaprol
succimer
penicillamine
antidote for:

gold (3)
dimercaprol
succimer
penicillamine
antidote for:

mercury (2)
dimercaprol
succimer
antidote for:

cyanide (3)
nitrite (forms methemoglobin)
thiosulfate (forms methemoglobin)
hydroxocobalamin
antidote for:

CO (2)
100% O2
hyerbaric O2
antidote for:

methanol and ethylene glycol (3)
ethanol
fomepizole
dialysis
antidote for:

TCA's
NaHCO3
antidote for:

heparin
protamine
antidote for:

warfarin (2)
vit. K
FFP
antidote for:

tPA or streptokinase
aminocaproic acid
sideroblatic anemia caused by
lead poisoning

(ringed sideroblasts contain Fe around the periphery)
wrist and foot drop seen with
lead poisoning
causal agent:

atropine-like SE's
TCA's

(TCA's are anti-cholinergic)
causal agents:

cutaneous flushing (4)
Ca2+ channel blockers
niacin
adenosine --> NO
vancomycin ("red man syndrome")
causal agents:

Torsades des pointes (3)
quinidine (class IA)
sotalol (class III)
cisapride
causal agents:

agranulocytosis (3)
clozapine
carbamazepine
colchicine
causal agents:

aplastic anemia (3)
chloramphenicol
benzene
NSAIDS
causal agents:

pulmonary fibrosis (3)
bleomycin
amiodarone
busulfan
causal agent:

acute cholestatic hepatitis
macrolides
causal agents:

hepatic necrosis (3 drugs; 1 fungus)
halothane
valproic acid
acetaminophen
Amanita phalloides
causal agent:

hepatitis
INH
causal agents:

pseudomembranous colitis (2)
ampicillin
clindamycin
causal agents:

gynecomastia (6)
spironolactone
cimetidine
ketoconazole
digitalis
chronic alcohol use
estrogens

(anti-androgen effects or pro-estrogen effects)
causal agents:

osteoporosis (2)
corticosteroids
heparin
causal agents:

photosensitivty (3)
sulfonamides
amiodarone
tetracylcines

(SAT for a photo)
causal agent:

tendonitis (adults)
tendon rupture (adults)
cartilage damage (children)
fluoroquinolones
causal agent:

Fanconi syndrome
expired tetracyclines
causal agent:

interstitial nephritis
methicillin
causal agents:

hemorrhagic cystitis (2)
cyclophosphamide
ifosfamide
causal agents:

cinchonism (2)
quinidine
quinine
causal agents:

diabetes insipidus
lithium
demeclocycline
causal agents:

seizures (2)
buproprion
imipenem + cilastatin
causal agents:

disulfiram-like reaction (4)
metronidazole
procarbazine
sulfonylureas
cephalosporins
causal agent:

nephrotoxicity/neurotoxicity
polymyxins
causal agents:

nephrotoxicity/ototoxicity (3)
aminoglycosides
loop diuretics
cisplatin
CYP450 inducers (7)
St. John's wort
Quinidine
Barbiturates
Phenytoin
Rifampin
Griseofulvin
Carbamazepine

(Saintly Queen Barb takes Phen-phen and Refuses Greasy Carbs )
CYP450 inhibitors (6)
INH
Sulfonamides
Cimetidine
Ketoconazole
Erythromycin
Grapefruit juice

(Inhibitors Stop Cyber-Kids from Eating Grapefruit)
methanol poisoning can lead to (2)
severe acidosis
retinal damage
herbal agent:

used to treat common cold

SE's include GI distress, dizziness, and headache
echinacea
herbal agent:

used to treat migraine

SE's include GI distress, mouth ulcers, and antiplatelet action
feverfew
herbal agent:

used to treat intermittent claudication

SE's include anxiety, insomnia, headache, and antiplatelet actions
ginkgo
herbal agent:

used to treat chronic anxiety

SE's include sedation, ataxia, hepatotoxicty, phototoxicity, and dermatotoxicity
kava
herbal agent:

used to treat viral hepatitis

SE's include loose stools
milk thistle
herbal agent:

used to treat BPH

SE's include decreased libido and hypertension
saw palmetto
herbal agent:

used to treat mild to moderate depression

SE's include phototoxicity, serotonin syndrome when taken with SSRI's, and induction of CYP450
St. John's wort
herbal agent:

used to treat symptoms in females with SLE or AIDS

SE's include androgenization in premenopausal women, estrogenic effects in postmenopausal women, and feminzation in young men
dehydroepiandrosterone
herbal agent:

used to treat jet lag and insomnia

SE's include sedation suppression of midcycle LH surge, and hypoprolactinemia
melatonin
"-azine" (2)
neuroleptic

antiemetic
"-ipramine"
TCA
"-tropin"
pituitary hormone