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26 Cards in this Set
- Front
- Back
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#1 drug for RSV?
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Ribavirin
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Used for influenza A only?
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Rimantidine
Amantidine Zanamivir |
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Used for Influenza A and B?
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Zanamivir
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Used for Rubella?
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Amantidine
Rimantidine |
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How does ribavirin work?
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Inhibits synthesis of guanine nucleotides
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Drug of choice for keratitis?
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Trifluridine (topical nucleoside analogue)
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Tx herpes?
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Acyclovir
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How do amantadine and rimantadine work?
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Block viral uncoating/penetration
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How do nucleoside analogues work?
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Phosphorylated by viral thymadine kinase (viral>>human), put into DNA, cause chain termination
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List nucleoside analogues.
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Acyclovir
Trifluridine Idoxuridine Vidarabine Ganciclovir |
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What are interferons used for?
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Block various stages of RNA/DNA synthesis.
Used with Ribavirin for Hep B and C |
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Mechanism of action for Zanamavir?
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neuraminidase inhibitor
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Pyrophosphate analalogue that has nephrotoxicity?
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Foscarnet (used for CMV if resistant to gancyclovir)
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Causes bone marrow suppression and is useful to Tx CMV?
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Gancyclovir (nucleoside analogue)
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Absorption of this antibiotic is inhibited by divalent cations (antacids)
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ciprofloxacin
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1st gen cephalosporin?
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cefazolin
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Best cephalosporin for gram + cocci?
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1st gen (cefazolin)
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Most widely used drug for surgical prophylaxis?
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Cefazolin
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#1 drug for H. flu middle ear infection?
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Cefaclor (2nd gen cephalosporin)
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Cephalosporin generation that works against gram - rods, especially psuedomonas?
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3rd (Ceftazidime)
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Generation of cephalosporins that works against Gram + cocci and Gram - rods?
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4th generation (cefepime)
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4th generation cephalosporin?
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Cefepime
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Inhibit 30S ribosome? 50S?
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30S: Aminoglycosides, Tetracycline
50S: Chloramphenicol, Erythromycin (macrolides), cLindamycin buy AT 30 CELl at 50 |
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Inhibits DNA gyrase activity in bacteria?
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Quinolones (Cipro)
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Tx liver stage malaria?
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Primaquine (P. ovale, P. vivax)
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#1 amebiasis, #1 giardia, #1 Trichomonas?
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Metronidazole
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