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129 Cards in this Set
- Front
- Back
hydrocodone bitartrate (Hycodan)
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opiod agonist
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oxycondone hcl (oxycontin)
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opiod agonist
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hydormorphone hcl (dilaudid)
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opiod agonist
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meperidine HcL (demerol)
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opiod agonsit
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morphine sulfate (duramorph)
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opiod agonist
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hydrocodone/acetaminophen (vicodin)
Oxycodone hcl/ " (percocet) propoxphene napsylate/ " (darvocet) |
combination meds (opiod)
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when an opiod is reversed a pt will have what sx?
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increase BP, tremors, hypervent., n and v, rapid loss of analgesia
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these 2 drugs can be used for opiod dependence
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methadone (dolophine).doesnt cause euphoria
buprenorphine (subutex) Sublingual |
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NSAIDS..antipyretic,antiinflamatory, analgesics...
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choice for mild to mod pain..esp w inflamation...
asprin (ASA) ibuprofen ketorolac tromethamine (Toradol) Naproxen Na (aleve) Celecoxib (celebrex) --Cox-2 inhibs are.... |
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Acetaminophen
Clonidine (Catapress) Tramadol (Ultram) |
non-opioid analgesics
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What drugs stop a migrane in progress?..2 categories...both stimulate serotonin (5-HT)
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Triptans
Ergot alkaloids |
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triptans (3)..constrict blood vessels in the brain
SE? |
sumatriptan (imitrex)-
rizatriptan (Maxalt)--HA zolmitriptan (zomig) dizziness/warmness/drowsiness |
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ergot alkaloids (1)
side effects interacts w which receptors (3) |
Ergotamine (ergostat)
preg X and dependency interact w adrenergic, dopaminergic, and serotonin receptors promotes vasoconstriction and stop migrane |
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beta-blockers for migrane prophylaxis
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propranolol Hcl (inderal)
metoprolol ( lopressor) |
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calcium channel blockers unlabeled for migrane prophylaxis
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verapamil (calan)
nifedipine (procardia) |
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TCA for unlabeled migrane prevention
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amitriptyline hcl (elavil)
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antiseizure for migrane prevention
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valproic acid (depakote)
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local anesthetics loss of sensation is lost but not consciousness..topical, infiltration, nerve block, spinal, epidural...
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Procaine (Novocian)--ester
lidocaine (xylocaine)--amide |
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the only gas given for anesthesia
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nitrous oxide(laughing gas)
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seizures are most common in groups
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male less than 20 or older than 60
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febrile seizures ane mc in kids 3 mo-5yr
acetaminiophen,profen, tepid baths antiepileptic only used for.. |
underlying neuro deficiit
complex febrile seizure repeated siezures in same illiness onset under 6mo or more 3 in 6 mo. |
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Barbiturates have declined in use for several reasons...
they are still used for...anticonvulsants iv anesthetics death inducing agent -are not analgesics..no sleep c pain suppresses rem sleep--no dreams |
lethal in od
narrow therapeutic to toxic range high tolerance,dependence, and abuse interact dangerously w Etoh |
|
barbituates produce tolerence by drug metb agents in the liver and
adaptation of neurons in brain 2 examples? withdraw? |
phenobarbital (luminal)-iv/im/po wt based
secobarbital (seconal) im/iv withdraw hallucinations, restless,disoreinted |
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Benzodiazepines
wide margin of saftey, fatal w other CNS depressants, schedule IV (some abuse potential) uses? contraindications? |
seizures,anxiety,etoh wdraw, muscle spasms
Contra- repir do, severe liver/kidney do, hypersensitivity, hitory of Etoh or durg abuse. |
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MIsc seizure drugs
this one is also for neruopathy/anxiety? se? this one also treats migranes? se? |
Gabapentin (neurontin)
-sedation, drowsy,dizzy,blurry vision, false positive protein in urine topiramate (topamax) -sedation, drowsy, dizzy, v sweating and overheating, may v birth control- |
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Hydantoin and phenytoin-like drugs delay the infulx of na across neruronal membranes,(not blocked)
Most prescribed hydantoin se? |
Phenytoin (dilantin)
doesnt cause sedation or abuse pt serum levels monitor close (narrow) -gingival hyperplasia, dysrhythmias, severe hypotns and cns rxs, peripheral neuropathy(long use) , skin rxs |
|
phyenytoin-like drugs--action like hydantoins w. less se
2 examples? SE? |
carbamezepine (tegretol)
valproic acid (depakote) drowsy, gi upset,prolonged bleeding, tremor, alopecia |
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succinmides.
delay ca entry and increase electricla threshold Example se |
ethosuximide (zarontin)
psychosis or extreme mood swing, including depression w suicidal intent dizziness, ha,fatigue, lethargy,ataxia |
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phenothizine adn phenothiazine-type drugs for schizophreniza (psychoses)
3 examples? SE? |
chlorpromazine (thorazine)
mesoridazine besylate (serentil) Trifluperazine (stelazine) EPS-dystonia, akathisia, parkinsonisma and tardive dyskinesia anticholinergic, sedation, hypotns,sexual dsyfunction, and neruleptic malignant syndrome |
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nonphenothizine drugs (2)
same se as phenothiazines, w less sedation. |
haloperidol (hadol)
pimozide (orap) |
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atypical antipsychotic agents have a broader specturm of action and do not have EPS.
examples (4) se? |
clozapine (clozaril)
risperidone (risperdal) aripiprazole (abilify) quetiapine fumarate (seroquel) wt gain, menstrual ireg, OP in women, decreased libido, altered glc. metabolism, HA, NV, fever, constipation,anxiety |
|
meds for parkinsons restore balance of dopamine and acetylcholine
dopaminergic agents (4) se? |
levodopa (l-dopa)
carbidopa levodopa (sinemet) ropinirole hcl (requip) pramipexole (mirapex) ivol. movements, loss of appetite, nv, orthostatic hypo. |
|
cholinergic blockers block acetylcholine which inbhibits its overactivity(3)
-these are less efft. vs dopaminergic, used early when dopa not tolerated |
benzotropine mesylate (cogentin)
diphenhydramine hcl (benadryl) trihexyphenidyl (artane) dry po, blurred vision, tachycardia, urinary ret., constipaiton |
|
alz. drug improve cognitive funt. and slow memory loss, pt. lives 5-10 years
Acetylcholinesterae inhibitors are most widely used (3) se? |
prevent acetylcholine from degrading
Donepenzil hcl (aricept) galantamine (reminyl) rivastigmine tartate (exelon) nv, diarrhea, wt loss, hypotn, liver toxicity |
|
MS (RRMS)
these reduce inflamation and PREVENT attacks of NS. Immunostimulants (2) Myelin protien builders (1) |
-interferon beta-1a (avonex)
-interferon beta-1b (betaseron) se- flu-like, nv,diarrhea, anorexia glatiramer acetate (copaxone)-PFS last several days.... se: inj site hurts, flushing, chest pain, weakness, infection, pain, n, joint pain, anxiety, muscle stiffness |
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meds to relieve MS symptoms (4)
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Modafinil (provigil)
amantadine (symmetrel) gabapentin (neurontin) Methylpredinisolone (solu-medrol) |
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Cns receives signals from sensory recptors?
cns sends out signals to body--nerves? |
afferent
efferent (peripheral is all nerves outside cns) |
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sympathetic ns--
primary nuerotransmitter? called--fibers? |
increase heart
promotes breathing dialate pupils relax bladder inhibits sex organs and digestion adrenergic norepinephrine |
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parasympathetic ns-cholinergic
primary nuerotransmitter? |
acetylcholine
constricts pupils stim saliva and digestion and gallbl. slow heart contracts bladder |
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adrenergic agents..multiple receptors..
alpha-1? alpha-2? beta 1? beta-2? dopaminergic? |
-vasoconstriciton of blood vessels
-neg. feedback&stop norepin. release -increase hr -relax smooth muscle bronchi,uertus, perp. arterial blood vessels -improves sx of parkinson & increases urine output |
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meds to relieve MS symptoms (4)
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Modafinil (provigil)
amantadine (symmetrel) gabapentin (neurontin) Methylpredinisolone (solu-medrol) |
|
Cns receives signals from sensory recptors?
cns sends out signals to body--nerves? |
afferent
efferent (peripheral is all nerves outside cns) |
|
sympathetic ns--
primary nuerotransmitter? called--fibers? |
increase heart
promotes breathing dialate pupils relax bladder inhibits sex organs and digestion adrenergic norepinephrine |
|
parasympathetic ns-cholinergic
primary nuerotransmitter? |
acetylcholine
constricts pupils stim saliva and digestion and gallbl. slow heart contracts bladder |
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adrenergic agents..multiple receptors..
alpha-1? alpha-2? beta 1? beta-2? dopaminergic? drugs are selective for beta1 or they are both beta 1 and 2.. |
-vasoconstriciton of blood vessels
-neg. feedback&stop norepin. release -increase hr -relax smooth muscle bronchi,uertus, perp. arterial blood vessels -improves sx of parkinson & increases urine output |
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meds to relieve MS symptoms (4)
|
Modafinil (provigil)
amantadine (symmetrel) gabapentin (neurontin) Methylpredinisolone (solu-medrol) |
|
Cns receives signals from sensory recptors?
cns sends out signals to body--nerves? |
afferent
efferent (peripheral is all nerves outside cns) |
|
sympathetic ns--
primary nuerotransmitter? called--fibers? |
increase heart
promotes breathing dialate pupils relax bladder inhibits sex organs and digestion adrenergic norepinephrine |
|
parasympathetic ns-cholinergic
primary nuerotransmitter? |
acetylcholine
constricts pupils stim saliva and digestion and gallbl. slow heart contracts bladder |
|
adrenergic agents..multiple receptors..
alpha-1? alpha-2? beta 1? beta-2? dopaminergic? drugs are selective for beta1 or they are both beta 1 and 2.. |
-vasoconstriciton of blood vessels
-neg. feedback&stop norepin. release -increase hr -relax smooth muscle bronchi,uertus, perp. arterial blood vessels -improves sx of parkinson & increases urine output |
|
examples of adrenergic agents (5) (aka sympathomimetics)
se |
dobutamine (dobutrex)
dopamine (inotropin) albuterol (proventil) epinephrine (adrenalin) norepinephrine (levophed) palpitations, tachycardia, skin flush, dizzy, tremors |
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adrenergic blockers (oposite action than if receptor was stimulated)
beta blockers (5) se? |
atenolol (tenormin -lol
propranolol (inderal) bradycardia, peripheral vasoconstriction( purple skin), bronchospasm (wheeze), h failure |
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alpha blockers (3)
uses se |
doxazosin, terazosin, prazosine
vasodilators.. htn,raynaud's relaxes smooth mus. bladder and prostate in BPH. se--orothostatic hypo, dizzy, n, bradycardia |
|
parasympathomimetics aka...
bethanechol (urecholine)? physostigmine (antilirium)? pilocarpine (isopto carpine)? pyridostigmine (metinon)? |
cholinergic agents
contracts bladder decrease intraocular pressure treat myasthenia gravis se: nv,diarrhea, abdonimal cramps, hypotn, dizzy |
|
anticholinergic agents aka
prevent the action of acetylcholine atropine? dicyclomine (bentyl)? glycopyrrolate (robinul)? se? |
dry secretions prior surgery, increase HR, dialate pupils
treat Ibs treat PUD, presurgry decrease salivation and bronchial secretions blurred vision, constipation, urinary retention, dry mouth/nose/throat |
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estrogen 3 different hormones?
functions? (3) ovaries stop producing at ? |
estradiol, estrone, estriol
mature repro organs secondary sex characteristics metb. effects on brain/kidney/bv/skin ----keep cholestrol low/ ca uptake 50-55 |
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progestrone functions?
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breat dev
regualates menstral cycle maintains endometrium in preg prevents premature contractions |
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hormones from pituitary
FSH? LH? |
regulates sperm and egg production
-triggers ovulation -promotes release of estrogen and prog. by ovary -reg. production of testosterone |
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most bc is estrogen and progestrone
stop fsh and LH preventing ovualation and uterus lining less favorable |
ortho-novum
monophasic-1mg/35mcg biphasic- progestin increase end/ 10/1...(35mcg/.5/1) triphasic-7/7/7-(35mcg/.5/.75/1mg) triphasic-e and p vary in 3 phases |
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long term birth control..
1.im injection of medroxyprogesterone acetate 2.transdermal patch estradiol and norelgestoromin) 3. vaginal ring(estrogen and prog.) 4.sq implant in arm (levonorgestrel) |
1. depo prover
|
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estrogen 3 different hormones?
functions? (3) ovaries stop producing at ? |
estradiol, estrone, estriol
mature repro organs secondary sex characteristics metb. effects on brain/kidney/bv/skin ----keep cholestrol low/ ca uptake 50-55 |
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progestrone functions?
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breat dev
regualates menstral cycle maintains endometrium in preg prevents premature contractions |
|
hormones from pituitary
FSH? LH? |
regulates sperm and egg production
-triggers ovulation -promotes release of estrogen and prog. by ovary -reg. production of testosterone |
|
most bc is estrogen and progestrone
stop fsh and LH preventing ovualation and uterus lining less favorable |
ortho-novum
monophasic-1mg/35mcg biphasic- progestin increase end/ 10/1...(35mcg/.5/1) triphasic-7/7/7-(35mcg/.5/.75/1mg) triphasic-e and p vary in 3 phases |
|
long term birth control..
1.im injection of medroxyprogesterone acetate 2.transdermal patch estradiol and norelgestoromin) 3. vaginal ring(estrogen and prog.) 4.sq implant in arm (levonorgestrel) |
1. depo provera
2.ortho-evra 3 nuvaring 4.norplant |
|
estrogen 3 different hormones?
functions? (3) ovaries stop producing at ? |
estradiol, estrone, estriol
mature repro organs secondary sex characteristics metb. effects on brain/kidney/bv/skin ----keep cholestrol low/ ca uptake 50-55 |
|
progestrone functions?
|
breat dev
regualates menstral cycle maintains endometrium in preg prevents premature contractions |
|
hormones from pituitary
FSH? LH? |
regulates sperm and egg production
-triggers ovulation -promotes release of estrogen and prog. by ovary -reg. production of testosterone |
|
most bc is estrogen and progestrone
stop fsh and LH preventing ovualation and uterus lining less favorable |
ortho-novum
se: thromboembolism, throbosis, thrombophlebitis,smoke ^ cardio monophasic-1mg/35mcg biphasic- progestin increase end/ 10/1...(35mcg/.5/1) triphasic-7/7/7-(35mcg/.5/.75/1mg) triphasic-e and p vary in 3 phases |
|
long term birth control..
1.im injection of medroxyprogesterone acetate 2.transdermal patch estradiol and norelgestoromin) 3. vaginal ring(estrogen and prog.) 4.sq implant in arm (levonorgestrel) |
1. depo provera
2.ortho-evra 3 nuvaring 4.norplant |
|
progestin only bc produce thick mucus at uterus enterance
less effective higher menstral ireg for pt high risk w. estrogen |
micronor
NOr-QD ovrette s |
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hormone replacement therapy
increased risk of... estrogen? |
cad, stroke, venous throboembolism
1.conjugated estrogens (premarin) and conjugated estrogens w medoxprogesterone(prempro) for menopause/ se same as bc 2.prostate cancer..supress androgens.. |
|
what are hrt progestins used for?
androgens? progestins?..example |
1. palliatively, endometrial cancer
2. breast cancer 3. dysfunt. uterine bleeding.. medroxyprogesterone (provera) |
|
oxytocin functions?
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stim. uterine contractions at birth
eject milk after delivery (sucking stims oxytocin release) Oxytocin (pitocin, syntocinon) |
|
what are some other drugs that stimulate uterine contractions? (2)
|
dinoprostone (cervidil)
mifepristione (mifiprex) |
|
Tocolytics inhibit uterine contractions during premature labor (3)
|
magnesium sulfate
nifedipine (procardia) terbutaline sulfate (brethine) |
|
lack testosterone in males..impotence and low sperm...may due to.....
pituitary do, hereditary, unknown..... androgen drug therapy..? |
testosterone base (andro)
promotes gonadal dev may restore normal repro treat certain breast cancer w antineo. |
|
testosterone like components w hormaonal activity, taken wrong way to build muscles, prolonged use has adverse effects?
|
anabolic steroids
raise cholesterol low sperm/impotence menstrual ireg increase man in women permanent liver damage behv. changes psychological dependence |
|
BPH..sx..increased urinary freq, and urgency, excessive nighttime urination, decreased force, feeling cant empty bladder all the way.
treat? (allieviate symptoms--take forever) |
alpha 1 adrenergic blockers
-doxazocin (cardura) terazocin (hytrin) tamsulosin (flomax) finasteride (proscar)- |
|
Histamine is released by mast cells.
dialates blood cells, sm contraction, tissue swelling,itching....anaphylaxsis two kinds histimine receptors? s |
h1- vascular, bronchiol, dig...
blocker for allergies/inflam h2-stomach hcl-blocker for PUD |
|
too much aspirin can lead to salicylism..sx.?
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tinitus, Ha, sweat
|
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glucocorticoids used for severe inflamation.
se? |
dexamethasone (
methylpredinisolone (medrol) prednisolone (delta-cortef) prednisone se: ^blood glc., mood changes, cataracts, PUD, lyte imbalance, OP dont use in myasthena gravis, barbituates &phenytoins ^ prednisone metb., inhibit antibody to vaccines |
|
allergic rhinitis: rhinorrhea, conjuctivitis, itchy eyes,ears
treat w. |
antihistimines
intranasal coricosterod anti-infl sypathomimetics |
|
antihistimines..doc for allergic rhinitisis
(DO NOT V NASAL CONGESTION) relieve runny nose and itching motion sickness/ vertigo |
avoid etoh-seditive may addictive
1st gen drowsiness new dont 1st.chorpheniramine (chlor-trimeton) diphenhydramine hcl (benadryl) 2nd..cetirizine (zyrtec) lorataine (claritin)-empty stom. |
|
antihistimines se?
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drowsiness, impaired memory or coordination, constipation, dry po
|
|
intranasal corticosteroids..highly effective in reducing intranasal infl.
|
budesonide (rhinocort aqua)
fluticasone (flonase) mometasone (nasonex) triameinolone (nasacot AQ) |
|
sympathomimetics (decongestants) for allergic rhinitis(3)
what may develop from thier use? |
oxymetazoline (afrin)
phenylephrine (neo-synephrine) pseudoephedrine (sudafed) rebound congestion (rhinitis medicamentosa) 3-5 days lA 2-3 weeks SA |
|
decongestants should be used w caution in pt w.?
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htn
hyperthyroid dm cardiac disease increased intraocular pressure prostatic hyperplasia (bph) |
|
biological drugs used to prevent illiness..the immune system responds in weeks or months....3 types of vaccine suspensions...?
|
killed microbes
weakened microbes bacterial toxins..toxoids - hazardous |
|
types of vaccines
|
DTP
hep B influenza MMR poliovirus (orimune) varicella zoster (varivax) anthrax--cdc selecte pop |
|
biological response modifiers aka immunostimulants...
interferons (3) interleukins (3) |
interferon alfa 2a: luekemia,kaposis
interferon alfa 2b:chronic hep b or c interferon beta: MS aldesleukin(proleukin) met. renal ca prelvekin (neumega) stim platletes |
|
immunosuppresants.(4)
1. also for severe RA..v BM, skin ca, lymphoma 2.begin b4 surgery, also for RA & severs psoriasis.. se:v urine,tremor,htn,^ hepatic inf 3.blocks folic acid metb.,also for neoplasia, severe psoriasis & RA. se: death, kidney/lung/liver damage, birth defects 4.begin wi 24 hrs of transplant Dml-rare brain inf.., abortion, ^ ca. |
1.azathioprine (imuran)
2.cyclosporine (neoral) 3.methotrexate (AMETHOPTERIN) 4.mycophenolate mofetil (cell cept) |
|
?CMF
CAV? CHOP? ca meds have serious toxicity..se? |
breast
lung non-hodgkins anemia/thrombocytopenia/leukopenia/n/v/diarrehea/anoxeriz/fatigue/inft/ulcers/alopecia |
|
these growth factors are used to increase wbc in ca pt. (2)
|
filgrastim (neupogen)
sargramostim (leukine, prokine) |
|
most widely used antineoplastic drugs
alkylating agents (2) |
cyclophosphamide (cytoxan)
nitrogen mustard -v dig, anticog ^ hemmorage w. insulin =hypogly., leukopenia cisplatin (platinol) misc. - bone marrow supression |
|
amtimetabolites..chemically similar to building blocks of cell (2)..disrupt metb.
|
Methotrexate (mexate)
antifolate flourouracil (5-fu) se: severe immunosupresant, bruising (v platletes), n, v, anorexia, rare- pulmonary toxicity preg X, nsaids=toxic |
|
antitiumor antibiotics..iv or directly in body cavities..not widely prescribed.
|
bleomyin (blenoxane)
doxorubicin (adrimycin)--irev. heart fail. |
|
1. vica alkaloids (2). periwinkle plant
2. taxoids (2). pacific yew |
1. vincristine (oncovine)-ns toxicity
monitor peripheral nueropathy. vinblastine ( velban) 2. docetaxel (taxotrene) paclitaxel (taxol) |
|
hormone for ca
1. breast/ prostate 2. uterine/renal 3. breast |
1.ethinyl estradiol (estinyl)
2.medroxyprogesterone (provera) 3. testosterone (deltatest) |
|
hormone antagonists
1. adv prostate 2. breast-widely used...also for high risk prevention. se? |
1. louprolide (lupron)
2.tamoxifen (nolvadex) ^ uterine ca risk, hot flashes, fluid ret., venous clots, abnor. bleeding |
|
biological response modifiers dont kill ca, but stimulate immune.
|
interferon alfa -2 (interon A)
rituximab (rituxan) flu-like sx, chills, fever, fatigue--usually diminish as progress,,,,nv,diarrhea, anorexia prolonged=heptatoxic/nuerotoxic/immune supression |
|
Penicillins..(oldest/safest)
b-lactaamase bacteria resistant...wide margin of saftey..many pt allergic, bacteria resitant |
carbenicillin
piperacillin ampicillin--broad/penicillinase resistant cloxacillin--penillinase resistane |
|
cephalosporins..(most widely prescr.)
serious gram neg. inf. and resistant or cant tolerate penicillin 1.b-lactamase rest. 2.more rest. 3.even more resist. LA/ broader 4. no etoh w/ use |
1.cefazolin (ancef)
cephalexin (kflex) 2. cefonicid (monocid) defuroxime (zinacet) 3.cefdinir (omnicef) ceftrizxone (rocephin) 4. cefepime ( maxipime) |
|
tetracyclines..broadest spectrum..used for few inf...- and +
rocky mtn/ lyme/ ulcers from h. plyori & chylamidia/ chorlea |
doxycycline (vibramycin)
minocycline ( minocin) tetracycline n/v/preg D---no milk (v 50%), under 9 yellow teeth, photosenst, broad spectrum= super inft. |
|
Macrolides--a safe alternative to penicillin.
se? |
azithromycin (zithromax)
clairthromycin (biaxin) erythromycin (e-mycin) mild-gi upset/diarreha/ abd pain/ superinf. |
|
aminoglycosides (bacteriocides)
serious - and + inft. (UTI) se? |
gentamicin
neomycin streptomycin tobramycin -otoxcity and nephrotoxic--most given parenterally |
|
flouroquinolones..(bacteriocide) ..gyne/resp/gi/ skin inft.
do not take w? se? |
ciprofloxacin (cipro)
levofloxacin (levaquin) moxifloxacin (avelox)--dsyrth. ofloxacin (floxin) --multivitamins or mineral --n/v/diarhhea--some dsyrth. |
|
sulfonamides (2)
.(bacterostatic)..inhibit FA..now widespread resist. many pt. allergic to sulfur se? |
sulfadizaine (RF pro)
bactrim n/v/crystals in urine |
|
mis atb..clindamycin (cleocin) for?
vancomycin (vancocin)? |
-po inft. for bacterocide species
-severe inf.. bacteria resist. to safer. red man syndrome..minor flushing upper body, hypotns....sometimes higher doses= Nephro and Ototoxicity |
|
oxazolindinones-(1) for mrsa
streptogamins (1)- for vanco rseist. |
linezolid (zyvox)
zuinupristin/dalfoprisitn (synercid) |
|
drugs for tb--combo used often
-prophalaxsis for exposure to tb/hiv? |
isoniazind (INH)-monitor liver ez.at
least monthly rifampin (rifadin) streptomycin pyrazinamide -pyrazinamide and INH |
|
systemic antifungals (4)
used to be 1st choice--now other safer exsist? |
-amphotericin B (fungizone)-
nephrotoxic--fever and chills at begin treatment, subsides..phlebitis w iv -fluconazole (diflucan) -itraconazole (sporanox) -ketoconazloe (nizoral) |
|
topical antifungals(4)
|
miconazole (micatin, monostat)
nystatin (mycostatin, nilstat)-candidia terbinafine (lamisil) tolnaftate (aftate,tinactin) |
|
antiretrovirals-
non-nucleoside reverse transcriptase inhibitors (NNRTI) bind to reverse transcrptase (2) |
delavirdine (rescriptor)
nevirapine (viramune) |
|
antiretrovirals-
nucleoside reverse trancriptase inhibitors (NRTI) (3) |
abacavir (ziagen)
stavudine (zerit,d4t) zidovudine (retrovir, azt)---severe toxictiy to blood (leuko- & anemia), many gi sx-n/v/diarhea, fatigue,wkness, caution w/ acetaminophen and st johns wart |
|
antiretrovirals--protease inhibitors-
block final assembly, resist quickly dev |
amprenavir ( agererase)
idinaivir ( crixivan) ritonavir (norvir)--give both 1-2 hrs b4 or after meal.. |
|
antiretrovirals for herpes
|
acyclovir (zovirax)--possible
nephrotox., painful vessel at infusion site docosanol (abreva) penciclovir (denavir) valacyclovir (valtrex) |
|
antivirals for influenza prevention
|
amantadine (symmetrel).also
parkinsons rimantadine (flumadine) |
|
amebicides for travelers diarrhea and malaria prophylaxsis.
for acute and chronic amebiasis, can cause otoxicity |
doxycycline (vibramycin)
paromomycin (humatin) |
|
antimalaria..doc..also for RA and amebiasis....im/iv...po ineffective
|
choroquine (plaquenil)
|
|
drugs for tb--combo used often
-prophalaxsis for exposure to tb/hiv? |
isoniazind (INH)-monitor liver ez.at
least monthly rifampin (rifadin) streptomycin pyrazinamide -pyrazinamide and INH |
|
systemic antifungals (4)
used to be 1st choice--now other safer exsist? |
-amphotericin B (fungizone)-
nephrotoxic--fever and chills at begin treatment, subsides..phlebitis w iv -fluconazole (diflucan) -itraconazole (sporanox) -ketoconazloe (nizoral) |
|
topical antifungals(4)
|
miconazole (micatin, monostat)
nystatin (mycostatin, nilstat)-candidia terbinafine (lamisil) tolnaftate (aftate,tinactin) |
|
antiretrovirals-
non-nucleoside reverse transcriptase inhibitors (NNRTI) bind to reverse transcrptase (2) |
delavirdine (rescriptor)
nevirapine (viramune) |
|
antiretrovirals-
nucleoside reverse trancriptase inhibitors (NRTI) (3) |
abacavir (ziagen)
stavudine (zerit,d4t) zidovudine (retrovir, azt)---severe toxictiy to blood (leuko- & anemia), many gi sx-n/v/diarhea, fatigue,wkness, caution w/ acetaminophen and st johns wart....take every 4 hours! |
|
antivirals for herpes
|
acyclovir (zovirax)-may cause nephrotox, pain vessel w iv
docosanol (abreva) penciclovir (denavir) valacyclovir (valtrex) |
|
influenza drugs
|
amantadine (symmetrel)- also for
parkinsons rimantadine (flumadine) |
|
helminth and protozoal inft.
AMIBICIDES |
doxycycline (vibramycin)-also
travelers diarrhea, malaria prevent paromomycin (humatin)--ototoxicity |
|
antimalarias
|
hydorxycholorquine (plaquenil)
choroquine (aralen)--doc-also for RA- oral ineffective |