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30 Cards in this Set
- Front
- Back
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Ca channel blockers:
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Nifedipine, nicardipine, verapamil
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Ca channel blockers MOA:
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Block Ca release from SR; block Ca channels
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Ca channel blockers result in:
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Relaxation of smooth muscle
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Has fewer s/e on cardiac conduction
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Nifedipine
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Has less effect on electrolytes:
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Nifedipine
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Has most effect on uterus compared to others:
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Nifedipine
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Nifedipine maternal s/e:
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Facial flushing, H/A, N
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Nifedipine fetal s/e:
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Animal studies - decrease UBF and acidosis
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Caution with using inhalational agents when a pt is on:
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Nifedipine
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Pt's can have _____ when on nifedipine
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Conduction abnormalities
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Pt's can have _____ when on nifedipine
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Vasodilation
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May need to go to second line stimulants earlier in pts who are taking this if they have hemorrhage
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Nifedipine
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Nifedipine causes:
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Uterine atony and PP hemorrhage unresponsive to uterine stimulants
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Oxytocin antagonist. Not approved by FDA yet
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Atosiban
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Atosiban blocks oxytocin at the:
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Cellular level
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Antihypertensives
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Hydralazine, NTG, Na NTGprusside, esmolol, labetalol
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Slower acting than labetalol
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Hydralazine
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Hydralazine is used in tx of:
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PIH
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OB fav
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Hydralazine
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Direct arteriolar dilator
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Hydralazine
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Hydralazine has little:
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Venous effect
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Hydralazine has more _____ than _____ effects
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Diastolic; systolic
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Hydralazine may cause an increase in:
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HR, SV, CO
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Is a pulmonary vasodilator:
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Hydralazine
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Hydralazine is mainly metabolized by:
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Liver
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Hydralazine: ______ is excreted unchanged
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15%
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Hydralazine s/e:
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Neuropathy, H/A, palpitations, anorexia, N/V, dizziness, sweating
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Smooth muscle relaxant and vasodilator
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NTG
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NTG is used as an:
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Antihypertensive - PIH
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NTG is used to:
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Blunt response to laryngoscopy
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