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85 Cards in this Set
- Front
- Back
onset 30 min to 1 hr
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short-acting
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onset 1 to 2 hrs
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intermediate-acting
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onset 4 to 8 hrs
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long-acting
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peak 2 to 4 hrs
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short-acting
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peak 6 to 12 hrs
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intermediate-acting
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peak 14 to 20 hrs
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long-acting
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duration 6 to 8 hrs
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short-acting
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duration 18 to 24 hrs
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intermediate-acting
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duration 24 to 36 hrs
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long-acting
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normal blood glucose
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60 to 100 mg/dl
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normal serum glucose
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70 to 110 mg/dl
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a chronic disease resulting from deficient glucose metabolism; is caused by insufficient insulin secretion from the beta cells, is a disorder of the pancreas
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diabetes mellitus
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hyperglycemia range
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>250 mg/dl
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hyopoglycemia range
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<60 mg/dl
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classic sx's (3 p's) of diabetes mellitus
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polyuria (increased urine output)
polydipsia (incresed thirst) polyphagia (increased hunger) |
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h/a
light-headedness nervousness apprehension tremor excess perspiration cold, clammy skin tachycardia slurred speech memory lapse confusion seizures |
hypoglycemia
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extreme thirst
polyuria fruity breath odor kussmaul breathing (deep, rapid, labored, distressing, dyspnea) rapid, thready pulse dry mucous membranes poor skin turgor |
hyperglycemia
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cultural occurrences of diabetes mellitus in the 45 to 65 age group that have hight incidences than whites
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african americans
native americans hispanics |
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6 criterias for using oral hypoglycemic agents
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-onset of diabetes mellitus at age 40 years or older
-dx of diabetes for <5 years -normal weight or overweight -fasting blood glucose =<200 mg/dl -<40 units of insulin required per day -normal renal and hepatic function |
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what are hyperglycemic agents used for
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to increase blood sugar
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a disorder indicated by a decresed t4 level and a normal or elevated TSH level
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thyroid disorder
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an increase in circulating t4 and t3 levels, which results from an overactive thyroid gland or excessive output of thyroid hormones from one or more thyroid nodules
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hyperthyroidism
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the most common type of hyperthyroidism caused by the hyperfunction of the thyroid gland; also call thyrotoxicosis
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grave's disease
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influenced by ACTH, which is released from the anterior pituitary gland; affect carbohydrate, protein and fat metabolism as well as muscle and blood cell activity
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glucocorticoids
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the second type of corticosteroid that secretes aldosterone
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mineralocorticoids
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reaction caused when more insulin is administered than is needed for glucose metabolism
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hypoglycemic reaction or insulin shock
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never give this rx in the arm
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symlin
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called the master gland because it secretes hormones that stimulate the release of other hormones from the target glands (including the thyroid, parathyroids, adrenals and gonads)
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pituitary gland
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controls the synthesis and release of hormones from the thyroid, adrenals and ovaries
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anterior pituitary gland
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enhance insulin secretion, delay gastric emptying and decrease food intake
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incretin mimetics
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gland located anterior to the trachea and has 2 lobes that secretes T4 and T3
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thyroid gland
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lie on the dorsal surface of the thyroid gland and secretes parathormone which regulates calcium levels in the blood
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parathyroid gland
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located at the top of each kidney and releases the catecholamines epinephrine and norepinephrine and is linked with the sympathetic nervous system
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adrenal glands
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located to the left of and behind the stomach; is both an exocrine (secretes digestive enzymes into the duodenum) and endocrine which has cell clusters call islets of langerhans
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pancreas
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hormones produced by the neurohypophesis
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ADH (vasopressin)
oxytocin |
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a group of antidiabetics chemically related to sulfonamides but lacking antibacterial activity, stimulate the beta cells to secrete more insulin
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sulfonylureas
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affect the hepatic and GI production of glucose
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nonsulfonylureas
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rx used for emergency hypoglycemic rx, acute tx of beta-blocker overdose and profound (insulin) shock
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glucagon
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rx used to tx chronic hypoglycemia caused by hyperinsulinism because of islet cell cancer or hyperplasia; hypotension usu does not occur; not indicated for hypoglycemia rxs
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diazoxide (Proglycem)
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rx improves glucose control in people with type 2 diabetes; not a substitute for insulin and should not be administered to pts with type 1 diabetes, diabetic ketoacidosis, severe renal dysfunction or severe GI disease
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exenatice (Byetta)
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rx for adults with type 1 and 2 diabetes; primary purpose is to improve postprandial glucose control in pts who are using insulin but are unable to achieve and maintain glucose control; never give in the arm
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pramlintide acetate (Symlin)
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hormones produced by the adenohypophesis
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thyroid-stimulating (TSH)
adrenocorticotropc (ACTH) donadotropins (follicle-stimulating) FSH luteinizing (LH) growth (GH) prolactin (PL) melanocyte-stimulating (MSH) |
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somatropin (Humatrope)
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anterior pituitary agent
growth hormone |
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octreotide (Sandostatin)
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anterior pituitary agent
growth hormone |
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levothyroxine sodium (Synthroid)
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thryoid replacement for hypothyroidism
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liothyronine (Cytomel)
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thyroid replacement for hypothyroidism
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methimazole (Tapazole)
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antithyroid rx for hyperthyroidism
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propylthiouracil (PTU)
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antithyroid rx for hyperthyroidism
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calcitrol (Rocaltrol)
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parathyroid hormone used to tx hypoparathyroidism and hypocalcemia
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calcitonin
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parathyroid hormone used to tx hyperparathyroidism and hypercalcemia
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glucocorticoids
mineralocorticoids |
adrenal hormones
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prednisone (Deltasone)
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adrenal hormones
intermedate-acting glucocorticoids |
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hydrocortisone (Cortef)
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adrenal hormones
short-acting glucocorticoids |
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fludrocortisone (Florinef)
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adrenal hormones
mineralocorticoids |
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vasopressin (Pitressin)
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posterior pituitary agent
ADH |
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desmopressin (DDAVP)
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ADH
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lispro (Humalog)
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rapid-acting insulin
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regular (Humulin R)
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rapid-acting insulin
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NPH insulin
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intermediate-acting insulin
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Humulin N
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intermediate-acting insulin
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glargine (Lantus)
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newer long-acting insulin
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humulin 70/30
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combination insulin
70% NPH 30% regular |
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glipizide (Glucotrol)
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oral antidiabetic agent
1st generation sulfonylureas |
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glimepiride (Amaryl)
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oral antidiabetic agent
2nd generation sulfonylureas |
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metformin (Glucophage)
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oral antidiabetic agent
nonsulfonylureas biguanides |
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acarbose (Precose)
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oral antidiabetic agent
alpha-glucoside inhibitor |
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insulin-enhancing agents
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thiazolidinediones
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rosiglitazone (Avandia)
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oral antidiabetic agent
thiazolidinedione |
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repaglinide (Prandin)
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oral antidiabetic agent
meglitinides |
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byetta
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incretin mimetics
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sumlin
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incretin mimetics
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glucagon
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hyperglycemic rx
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diazoxide (Proglycem)
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hyperglycemic rx
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somatropin (Humatrope)
ocetreotide (Sandostatin) |
anterior pituitary agents
growth hormones |
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levothyroxine sodium (Synthroid)
liothyronine (Cytomel) methimazole (Tapazole) propylthiouracil (PTU) |
thyroid hormones
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calcitrol (Rocaltrol)
calcitonin |
parathyroid hormones
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glucocorticoids
mineralocorticoids |
adrenal hormones
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prednisone (Deltasone)
hydrocortisone (Cortef) fludcortisone (Florinef) |
adrenal hormones
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vasopressin (Pitressin)
desmopressin (DDAVP) |
posterior pituitary agents
ADH |
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sulfonylureas
nonsulfonylureas biguanides alpha-glucoside inhibitors thiazolidinediones meglitinides |
oral antidiabetic agents
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glipizide (Glucotrol)
glimepiride (Amaryl) metformin (Glucophage) acarbose (Precose) rosiglitazone (Avandia) repaglinide (Prandin) |
oral antidiabetic agents
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Byetta
Symlin glucagon diazocide (Proglycem |
incretin mimetics
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glucagon
diazoxide (Proglycem) |
hyperglycemic drugs
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a vitamin D analogue that promotes calcium absorption from the gi tract and secretion of calcium from bone to the bloodstream; given for the management of hypocalcemia
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calcitriol
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a hyperglycemic hormone secreted by the alpha cell of the islets of Langerhans in the pancrease used to to treat insulin-induced hypoglycemia
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glucagon
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