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208 Cards in this Set
- Front
- Back
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Chlorpheniramine
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1st gen H1 antagonist
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Diphenhydramine
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1st gen H1 antagonist
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Pyrilamine
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1st gen H1 antagonist
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Cyclizine
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1st gen H1 antagonist
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Promethazine
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1st gen H1 antagonist, anti adrenoceptor action = prevents ortho htn
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Cyproheptadine
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1st gen H1 antagonist and 5HT antagonist, prevents post gastrectomy dump syndrome
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Fexofenadine
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2nd gen H1 antagonist (doesn't pass BBB as well = less sleepy)
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Loratadine
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2nd gen H1 antagonist (doesn't pass BBB as well = less sleepy), aka Claratin
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Cetirizine
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2nd gen H1 antagonist (doesn't pass BBB as well = less sleepy)
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Acrivastine
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2nd gen H1 antagonist (doesn't pass BBB as well = less sleepy)
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Dexfenfluramine
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5HT anorectic
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Buspirone
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5HT1a agonist, anxiolytic
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Sumatriptan
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5HT1d/b agonist. Reduces migranes by vasoconstricting
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Ritaserine
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5HT2 antagonist. Reduces thromboxane formation
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Ondansetron
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5HT3 antagonist. Treats GI SE of chemo.
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Ketanserine
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5HT1c and 5HT2 antagonist. Used to treat HTN in the EU.
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Dinoprostane
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PGE2 analog which has an oxytocic use. Stimulates uterus contraction. Used for abortion in 2nd tri
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Misoprostol
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PGE1 analog and used in RU486 as a combo pill. Aka day after pill, used to induce uterine contractions and expel fetus. Also inhibits gastric secretion, used to tx ulcers.
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Alprostadil
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PGE1 analog. Used to maintain patency of ductus arteriosus. Has smooth muscle relaxing effect.
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Indomethacin
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COX1-I, NSAID
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Sulindac
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COX1-I, NSAID
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Ibuprofen
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COX1/2-I, NSAID
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Nabumetone
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COX2-I, NSAID
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Coxibs
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COX2-I, NSAID
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Naproxen
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COX1/2-I, NSAID
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Aspirin
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irreversible inhibition of COX1/2. Prophylactic for TIA/unstable angina. Degrades to salicyclic acid. Reduces thrombosis in coronary artery bypass, MI.
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Dexamethasone
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PLA2 inhibition by chelation of substrate, lipcortins, annexins, COX2 expression
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Celecoxib
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aka Celebrex. COX2-I for RA tx.
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Rofecoxib
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aka Vioxx. COX2-I for RA tx.
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Epoprostol
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PGI2 derivative used to treat primary pulm HTN
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Latanoprost
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PGF2alpha derivative. Topically active. Used to tx glaucoma.
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Carboprost tromethamine
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PGF2alpha derivative. Used for early/2nd trimes abortion.
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Dazoxiben
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TxA2 synthase inhibitor. Used to tx coronary artery dz
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Zileuton
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5LOX-I. Prevents exercise induced asthma
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Monteleukast
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aka Singulair. LT-R antagonist
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Zafirleukast
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LT-R antagonist
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Captopril
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ACE-I
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Enalapril
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ACE-I
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Ramipril
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ACE-I
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Losartan
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AT1-R antagonist. Same as ACE-I but no cough SE.
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Aliskiren
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inhibits catalytic activity of renin
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Verapamil
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CCB, phenylalkylamine. More selective for cardiac than vasc tissue. Tx angina, HTN, atrial arrhythmias, SVT due to AV reentry, vasc HA
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Nifedipine
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CCB, dihydropyridine. Tx angina, HTN. Short lived so must be taken 3-4X/day
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Amlodipine
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CCB, dihydropyridine. Tx angina, HTN. SE= ankle edema, Used to tx isolated systolic HTN in elderly.
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Felodipine
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CCB, dihydropyridine. Tx angina, HTN
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Isradipine
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CCB, dihydropyridine. Tx angina, HTN
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Nicardipine
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CCB, dihydropyridine. Tx angina, HTN, subarachnoid hemorrhage
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Diltiazem
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CCB, benzothiazipine. Tx angina, HTN, atrial arrhythmia. Used to slow AV node conduction in pts with afib.
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Bepridil
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CCB. Treats angina. Has Na channel blocking activity. Increaes risk of Torsades de Pointes
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Gallopamil
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CCB, phenylalkylamine. Used in the ED only
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Mimodapine
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CCB, dihydropyridine. Very lipophillic, used in subarrachnoid hemorrhage by decreasing vasospasms due to berry aneurysm.
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Ergonovine
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Ergot, amine side chain, reactive at 5HT-R
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Methyl ergonovine
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Ergot, amine side chain, reactive at 5HT-R
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Methysergide
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Ergot, amine side chain, reactive at 5HT-R
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Ergotamine
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Ergot, amino acid side chain, reactive at alpha and DA receptors
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Dihydroergotamine
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Ergot, amino acid side chain, reactive at alpha and DA receptors
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Bromocriptine
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Ergot, amino acid side chain, DA agonist, reactive at alpha and DA receptors
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Theophylline
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a methylxanthine. Poorly soluble and must be complexed with ethyldiamine to form aminophylline. Methylxanthines inhibit PDE and antagonise adenosine receptors.
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Amyl nitrite
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organic nitrate, liquid capsule, via inhalation, short acting, used recreationally as a "popper",
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Nitroglycerin
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organic nitrate, 3 molecules of NO2, encounteres nitrate reductase and releases NO, via transdermal, subQ, buccal, low oral bioavailbility due to liver
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Isosorbide dinitrate
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organic nitrate, can be given orally
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Atenolol
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B-blocker, decrease HR and contractility, reduces renin secretion.
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Metoprolol
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B-blocker, decrease HR and contractility,
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Propranolol
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B-blocker, decrease HR and contractility, also local anestheic, causes nightmares, contraindicated in HTN pts with peripheral vasc dz.
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Nadolol
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B-blocker, decrease HR and contractility
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Esmolol
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B-blocker, decrease HR and contractility, ZERO bioavailability. Used onlyin emergencies b/c it has fast and quickly ending action
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Clopidogrel
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ADP antagonist. Usd to tx unstable angina.
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Dipyridamole
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can cause coronary Steal syndrome
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Acetazolamide
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carbonic anhydrase inhibitor, decreased H+ secretion by the proximl tubule, diurectic, treats: glaucoma, acute mtn sickness, edema, antiepileptic, metabolic alkalosis.
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Dichlorphenamide
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carbonic anhydrase inhibitor, decreased H+ secretion by the proximl tubule, diurectic, treats: glaucoma, acute mtn sickness, edema, antiepileptic, metabolic alkalosis.
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Methazolamide
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carbonic anhydrase inhibitor, decreased H+ secretion by the proximl tubule, diurectic, treats: glaucoma, acute mtn sickness, edema, antiepileptic, metabolic alkalosis.
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Mannitol
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Osmotic diuretic. Restricts reabsorption across H2O permeable membranes. Used for glaucoma, high ICP, and anuria due to rhabdomyolysis. Causes hypovolemia. ContraI= CHF.
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Glycerin
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Osmotic diuretic. Restricts reabsorption across H2O permeable membranes. Used for glaucoma, high ICP, and anuria due to rhabdomyolysis. Causes hypovolemia. ContraI= CHF. Also a lubricant
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Furosemide
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Loop diuretic (inhibits Na/2Cl/K triporter), sulfonamide. High ceiling diuretic. Can cause acute reduction in pulm wedge pressure. Causes hypochloremic alkalosis with hypokalemia. Unergoes organic acid secretory mechanism. Loop diuretics are better for ppl with prexisting renal dysfxn. Combo with aminoglycosides can produce ototoxicity.
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Ethacrynic acid
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Loop diuretic (inhibits Na/2Cl/K triporter), NON-sulfonamide. Prodrug that joins with cystein to become active.
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Bumetanide
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Loop diuretic (inhibits Na/2Cl/K triporter), sulfonamide
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Torsemide
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Loop diuretic (inhibits Na/2Cl/K triporter), sulfonamide
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Probenecid
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used to treat gout, interferes with organic acid transport, block action of loop diurectics.
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Thiazide
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diuretic, inhibits Na/Cl symporter in distal convoluted tubule
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Hydrochlorothiazide
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thiazide-like, inhibits Na/Cl symporter in distal convoluted tubule. SE= hypocalciuria, hypokalemia, hyperglycemia, hyperuricemia.
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Indapamide
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thiazide-like, inhibits Na/Cl symporter in distal convoluted tubule
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Amiloride
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diuretic, inhibits renal ENaC, K-sparing diuretic, can be used to treat Liddle's syndrome.
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Triamterene
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diuretic, inhibits renal ENaC, K-sparing diuretic
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Spironolactone
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mineralcorticoid receptor antagonist. Can caused gynecomastia and Benign prostatic hyperplasia.
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Eplerenone
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mineralcorticoid receptor antagonist
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Conivaptan
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vasopressin receptor antagonist. Used to tx hyponatremia
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Sodium Bicarbonate
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irreversible , systemic, antacid. Produces alkalosis
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Magnesium hydroxide
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reversible, nonsystemic, antacid; can cause renal toxicity and diarrhea
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Aluminum hydroxide
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reversible, nonsystemic, antacid, can cause constipation
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Calcium Carbonate
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reversible, nonsystemic, antacid
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Pirenziepine
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M1 antagonist. Used to treat gastric acid production
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Telenzepine
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M1 antagonist. Used to treat gastric acid production
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Cimetidine
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H2-R antagonist, least potent, inhibits P450
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Ranitidine
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H2-R antagonist, mid-range potency, inhibits P450
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Famotidine
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H2-R antagonist, most potent.
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Nizatidine
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H2-R antagonist, mid-range potency,. Most bioavailable.
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Omeprazole
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H+K+ ATPase inhibitor (Proton pump inhibitor), prodrug
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Lansoprezole
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H+K+ ATPase inhibitor (Proton pump inhibitor), prodrug
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Misoprostol
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Prostaglandin, reduces acid. PGE-1 analog, only indicated for NSAID inudced ulcer treatment
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Sucralfate (carafate)
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in acid conditions, aluminum is lost leaving a polar anion. Anion binds to damaged areas and prevents further acid action
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Bismuth
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antimicrobial activitiy. Binds to affected areas and prevents further dmg. May inhibit theophylline metabolism.
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Metoclopramide
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DA antagonist with cholinomimetic properties. 5HT3/4 antagonist. Usd to tx nausea, vomiting assocaited with chemo. Increases gastric emptying and can be used to treat reflux
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Castor oil
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hydrolyzed to ricinoleic acid by pancreatic lipases to inc cAMP. Rapid onset (3h). Stimulant laxative
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Diphenylmethane
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stimulant laxative, effects on large I, 6hr onset
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Bisacodyl
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stimulant laxative, converted to active deactylated metabolite in colon. 6-8hr onset
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Phenolphthalein
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stimulant laxative
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Senna
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anthraquinone. stimulant laxative, converted to active aglyconse in colon, 6-8hr onset. Stimulate enteric nerve to increase motility
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Cascara
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anthraquinone. stimulant laxative, converted to active aglyconse in colon, 6-8hr onset. Stimulate enteric nerve to increase motility
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Aloes
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anthraquinone. stimulant laxative, converted to active aglyconse in colon, 6-8hr onset. Stimulate enteric nerve to increase motility
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Bran
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bulk laxative, increase fluid uptake, inc peristalsis, takes 1-3 days to act
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Psyllium
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bulk laxative, increase fluid uptake, inc peristalsis, takes 1-3 days to act
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Cellulose
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bulk laxative, increase fluid uptake, inc peristalsis, takes 1-3 days to act
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Dioctyl sodium sulfosuccinate
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surface acting, wetting agent, laxative. Lowers surface tension to allow fecal penetration by water. 1-3 day onset
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Polyethylene glycol
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electrolyte solution for rapid evauation of bowel, rapid effect
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Lactulose
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synthetic dissacharide used as a laxative. 1-3 day onset. Major use is reduction of blood ammonia in chronic portal HTN and hepatic encepalopathy
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Diphenoxylate
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meperidine analog. Tx diarrhea. Inhibits peristalsis. Combined with atropine (and called lomotil) to prevent abuse potential
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Loperamide
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piperidine analog. Doesn’t cross BBB. Used to tx diarrhea. Causes spastic contraction of intestinal muscle.
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Kaolin
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combined with opiates and binds intestinal wall to inhibit effect of the irritant. Anti-diarrhetic.
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Pancrelipase
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used for enzyme insufficiency. Replaces amylase, lipase, and protease
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Ursodiol
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dissolution of cholesterol gallstones. Takes 12-24 months to get rid of gall stones
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Amitryptyline
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TCAs that can be used to tx IBS
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Desipramine
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TCAs that can be used to tx IBS
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Lubiprostone
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PGE derivative. Activates type 2 Cl channel and inc Cl secretion. Treats constipation IBS
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Dicyclomine
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antispasmodic. Muscarinic antagonist used to tx IBS. Can cause blurry vision and dry mouth
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Hyoscyamine
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antispasmodic. Muscarinic antagonist used to tx IBS. Can cause blurry vision and dry mouth
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Alosetran
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5HT3 antagonist. For women w severe IBS w diarrhea. Only used in resistant cases
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Tegaserod
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5HT4 agonist. Used for women w IBS constipation. Withdrawn in 2007
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5-ASA
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aka 5-aminosalicyclic acid. Treats IBD (UC and chrons). Types are pentasa, asacol, lialda.
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Azathioprine
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Treats IBD (UC/crohns). Converted to 5-mercaptopurine.
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6-mercaptopurine
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Treats IBD (UC/crohns). Converted to thioguanine which has immunosuppresive activity
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Methotrexate
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treats IBD (UC/crohns). Maintains remission in crohns. Inhibits dihydrofolate reductase. Prevents synthesis of purines and thymididine. SE = BM suppression, megablastic anemia, alopecia.
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Infliximab
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TNFalpha antibody; treats IBD (UC/Crohn's); given IV
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Adalimumab
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TNFalpha antibody; treats IBD (UC/Crohn's); given subQ
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Certolizumab
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TNFalpha antibody; treats IBD (UC/Crohn's); given subQ
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Natalizumab
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anti-Integrin antibody (of alpha4 subunit). Used to tx severe Crohn's.
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Ondansetron
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5HT3 antagonist, used to tx chemo-induced nausea and vomiting
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Aprepitant
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neurokinin antagonist. Used to treat chemo-induced nausea and vomiting
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Droperidol
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treats nausea and vomiting. A phenothiazine
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Meclozine
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H1 and muscarinic antagonist. Treats motion sickness. No drowsyness
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Nabilone
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cannabinoid used to treat chemo-induced nausea and vomiting
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Dronabinol
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cannabinoid used to treat chemo-induced nausea and vomiting
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Scopolamine
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M antagonist. Used to treat motion sickness
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Guanethidine
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NE release inhibitor at the post gang sympathetic terminals. Lowers BP. SE = orthstatic hypotension, sexual dysfxn
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Methyldopa
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adrenergic inhibiting drug. Good for preecampsia (last tri of gestation). Converted to alphaNE, replaces NE in vesicles and is an agonist of the alpha2-R at the NTS
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Prazosin
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alpha1 antagonist. Acts by decreasing PVR to lower BP. SE = orthostatic htn, sexual dysfxn. Used to tx pheochromocytoma
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Hydralazine
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direct vasodilator of smooth muscle and activates K+ channels. Treats HTN. Not effective long term. Causes hyperpolarization whichclosesthe voltage gated Ca channels.
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Minoxidil
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direct vasodilator of smooth muscle and activates K+ channels. Treats HTN. Not effective long term. Causes hyperpolarization whichclosesthe voltage gated Ca channels. Can produce hirsutism (body hair) in women.
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Gemfibrozil
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Cholestyramine
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Clofibrate
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Atorvastatin
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Sildenafil
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inhibits PDE (like viagra)
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Atorvastatin
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hydroxyacid, HMG-CoA reducatase inhibitor. Toxicity = inc aminotransferase, myopathy, rhabdomyolysis; metab by CYP3A4 (inhib by grapefruit)
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Fluvastatin
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hydroxyacid, HMG-CoA reducatase inhibitor. Toxicity = inc aminotransferase, myopathy, rhabdomyolysis
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Pravastatin
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hydroxyacid, HMG-CoA reducatase inhibitor. Toxicity = inc aminotransferase, myopathy, rhabdomyolysis
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Lovastatin
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lactone, HMG-CoA reducatase inhibitor. Toxicity = inc aminotransferase, myopathy, rhabdomyolysis; metab by CYP3A4 (inhib by grapefruit). Di acid moiety. Pregnants should NOT take statins (hormone interference).
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Simvastatin
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lactone, HMG-CoA reducatase inhibitor. Toxicity = inc aminotransferase, myopathy, rhabdomyolysis; metab by CYP3A4 (inhib by grapefruit)
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Ezetimibe
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cholesterol absorption inhibitor from GI tract. Tox = hepatic impairment and myositis; does get absorbed
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Neomycin sulfate
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cholesterol absorption inhibitor from GI tract. Tox = hepatic impairment and myositis
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Cholestyramine
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bile acid sequestrant in the GI. Tox = constipation, bloating, steatorrhea. Does NOT get absorbed; interfere w digitalis and chlorothiazide absorption.
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Colestipol
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bile acid sequestrant in the GI. Tox = constipation, bloating, steatorrhea. Does NOT get absorbed. Some amide binding sites; interfere w digitalis and chlorothiazide absorption.
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Clofibrate
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increases lipoprotein lipase. Tox = rash, GI symp, myopathy
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Gemfibrozil
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increases lipoprotein lipase. Tox = rash, GI symp, myopathy
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Fenofibrate
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increases lipoprotein lipase. Tox = rash, GI symp, myopathy; PPAR alpha agonist. Can also displace warfarin from binding site.
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Nicotinic Acid
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inhibit syn of VLDL in liver; decrease Lpa (a thrombogenic lipoprotein). Tox = hepatotoxicity, ithcy, flushing, dec glucose tolerance, tachyphylactic.
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Digoxin
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dec Na/K ATPase activity causes inc intracell Na leads to inc intracell Ca leads to inc cardiac contractility. Has same effect as Bagonist but diff mechanism. Delays Na extrsuion. Does not affect Ca channels. Anti arrhythmics, macrolides, tetracycline cause dec clearance of digoxin --> toxicity. Serum digox level should stay below 1 ng/mL. Digox causes partial depol due to Na/K ATPase inhibition as well as inc CNS outflow. Causes decreased conduction velocity, shorter refractory period, and inc automaticity. Wider QRS.
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Dobutamine
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inc contractility via B1, reduced afterload via dilation due to partial agonist effect on A1. Used to tx CHF
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Dopamine
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inc contractility via B1, H2O and Na diuresis by vasodilating renal vascular bed.
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Aminophylline
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methyxanthine. 1st gen PDE-I. prevents cAMP breakdown and thus enhanced B1/B2 effects. Cardiac stimulation, vasodilation, bronchodilation
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Theophylline
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methyxanthine. 1st gen PDE-I. prevents cAMP breakdown and thus enhanced B1/B2 effects. Cardiac stimulation, vasodilation, bronchodilation
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Inamrinone
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bypyridine. 2nd gen PDE-I. prevents cAMP breakdown and thus enhanced B1/B2 effects. Cardiac stimulation, vasodilation, bronchodilation
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Milrinone
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bypyridine. 2nd gen PDE-I. prevents cAMP breakdown and thus enhanced B1/B2 effects. Cardiac stimulation, vasodilation, bronchodilation
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Sodium Nitroprusside
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dilate arterioles and veins
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Prazosin
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dilate arterioles and veins
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Phentolamine
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dilate arterioles and veins
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Phenoxybenzamine
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dilate arterioles and veins
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Nitroglycerin
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venodilator
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Isosorbide dinitrate
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venodilator
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Hydralazine
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arteriolar dilator
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Minoxidil
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arteriolar dilator
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Metoprolol
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B1 selective antagonist. Decrease renin release, dec HR and myo O2 consumption, down regulate B receptors, improve ventricular filling.
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Carvedilol
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non selective B antagonist. Also A1 antagonist so it dec afterload, O2 radical scavenging, anti-mitogenic. Decrease renin release, dec HR and myo O2 consumption, down regulate B receptors, improve ventricular filling.
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Quinidine
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dec conduction velocity via Na channel block; thus convert unidirectional to bidirectional block. K+ channel block = prolong refractory period. Used to treat supraventricular and ventricular arrhythmias. Tox = anitmuscarinic (dispyramide>quinidine>procainamide). Tox also = dec cardiac contractility, AV block, Torsade de Pointe, SA arrest, ventric tachy. GI distress, TTP, displaces digoxin.
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Procainamide
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dec conduction velocity via Na channel block; thus convert unidirectional to bidirectional block. K+ channel block = prolong refractory period. Used to treat supraventricular and ventricular arrhythmias. Tox = anitmuscarinic (dispyramide>quinidine>procainamide). Tox also = dec cardiac contractility, AV block, Torsade de Pointe, SA arrest, ventric tachy. GI distress, TTP, displaces digoxin. Lupus like reaction, ANA via CYP450.
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Dispyramide
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dec conduction velocity via Na channel block; thus convert unidirectional to bidirectional block. K+ channel block = prolong refractory period. Used to treat supraventricular and ventricular arrhythmias. Tox = anitmuscarinic (dispyramide>quinidine>procainamide). Tox also = dec cardiac contractility, AV block, Torsade de Pointe, SA arrest, ventric tachy.
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Lidocaine
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increase conduction veolicty, repol partially depol'd cells, inc outward K conductance. Tx ventricular arrhythmias. Hyperpolarize excitatory amino acid pathways. Sedation at therapeutic levels. Dec cardiac contractility, dec AV conduction, dec automaticity.
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Flecainide
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decrease conduction veolocity, widen QRS, Na channel blocker to make a bidirectional block. Tx PVCs, ventricular re entry, inhibit AV node conduction, WPW. Has risk of indicuing arthymias.
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Propanolol
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B blocker, treats supraventricular and ventricular arrhythmias. Tox = dec cardiac contractility, bradycardia, AV block, hypoglycemia, bronchospasm, rebount tachy.
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Esmolol
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B blocker, treats supraventricular and ventricular arrhythmias. Tox = dec cardiac contractility, bradycardia, AV block, hypoglycemia, bronchospasm, rebount tachy.
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Metoprolol
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B blocker, treats supraventricular and ventricular arrhythmias. Tox = dec cardiac contractility, bradycardia, AV block, hypoglycemia, bronchospasm, rebount tachy. Can be used on pts with asthma or hyperglycemia.
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Amiodarone
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prolong repol time. Block K+ channel, Na, Ca, and B blocker. Tx supraventricular and ventricular arrhythmias.Tox = dec contractility, bradycardia, AV block. Does not produce torsades de pointes. Non competitive B blcoker so CANNOT be overwhelmed by symp activity.
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Soltolol
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prolong repol time. Block K+ channel, Na, Ca, and B blocker. Tx supraventricular and ventricular arrhythmias.Tox = dec contractility, bradycardia, AV block. Risk of torsades de points. Competitive b blocking, so can be overwhelmed by symp activity.
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Bretylium
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prolong repol time. Block K+ channel, Na, Ca, and B blocker. Tx supraventricular and ventricular arrhythmias.Tox = dec contractility, bradycardia, AV block.
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Verapamil
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CCB Used to treat supraventricular arrhythmias. Tox = dec contractility, bradycarida, AV block, sinus arrest,
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Diltiazem
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CCB Used to treat supraventricular arrhythmias. Tox = dec contractility, bradycarida, AV block, sinus arrest,
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Adenosine
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treats PSVT. Good for acute care. Hyperpolarizes the AV node. Inc outward K conductance and hyperpolarizes the notes. Interrupts re entry thru AV node.
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Warfarin
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inhibits vit K dept gamma carboxylation of prothrombin. Tox = hemmorage or birth defects. Used to treat acute and chronic thromboembolism.
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Dabigatran
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direct thrombin hinhibitor. Goes right to active site of thrombin and blocks it. Prodrug. Converted by esterases. No hepatic of CYP involvment. So you can give a fixed dose. Tox = hemmorrhage. No antidote. Approved for clot prevention in a-fib.
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Unfractionated Heparin
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binds to antithrombin III and acts to inhibit thrombin and factor Xa, VIIa, Ixa. Longer t1/2 than heparin, safe during pregnancy, don’t need to monitor PTT. Tox = hemm, osteoporosis, HIT. Treat OD via protamine sulfate.
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LMW Heparin
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enoxaparin, dalteparin, danaproid and Fondaparinux. All are ATIII dependant.
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Lepirudin
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direct thrombin inhibitor. Binds directly to thrombin. Does not nead ATIII. Short acting, IV, no antidote, renal elimination.
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tPA
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alteplase, reteplase, tenecteplase. Selectively targeted to clots by a domain that binds to fibrin threads. Clot associated plasmin formed is resistant to plasmin inhibtiors. Tox = hemorrhage, strokes. OD tx = aminocaproic acid. Used to treat acute MI within 6 hrs, pulm emboli, central DVT, acute thrombotic stroke within 3 hrs.
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Aprotinin
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protease inhibitor used to inhibit endogenous plasmin. Inhibition of fibrinolysis. Reduces bleeding during sx.
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Clopidogrel
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inihibition of ADP receptors on platelets. Prodrug (actiated by CYP2C19), oral, delayed onset, Tox = hemm, skin rash, GI. Same use as aspirin.
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Prasugrel
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inihibition of ADP receptors on platelets. Prodrug, oral, delayed onset, Tox = hemm, skin rash, GI. Same use as aspirin.
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Abciximab
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GPIIb/IIIa receptor antagonist. Tox = bleeding, thrombocytopenia. Used to treat clot prevention. Mech = inhibits fibrinogen dept aggergation of actiated platelets.
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Epitifibatide
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GPIIb/IIIa receptor antagonist. Tox = bleeding, thrombocytopenia. Used to treat clot prevention. Mech = inhibits fibrinogen dept aggergation of actiated platelets.
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Tirofiban
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GPIIb/IIIa receptor antagonist. Tox = bleeding, thrombocytopenia. Used to treat clot prevention. Mech = inhibits fibrinogen dept aggergation of actiated platelets.
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