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73 Cards in this Set

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muscarine
muscarinic receptor agonist
nicotine
nicotinic receptor agonist (g& nmj)
atropine
muscarinic receptor antagonist
hexamethonium
nicotinic (g) receptor antagonist
tubocurarine
nicotinic (nmj) receptor antagonist
stimulates nicotinic and muscarinic receptors
acetylcholine
stimulates muscarinic receptors
muscarine
stimulates nicotinic receptors
(ganglionic & nmj)
nicotine
inhibits muscarinic receptors
atropine
inhibits nicotinic receptors (ganglionic)
hexamethonium
inhibits nicotinic receptors (nmj)
tubocurarine
acetylcholine
cholinergic receptor agonist
muscarinic & nicotinic (g & nmj)
epinephrine
sympathetic adrenergic receptor agonist
alpha-1, alpha-2, beta-1, beta-2
norepinephrine
alpha-1, alpha-2, beta-1 receptor agonist
phenylephrine
alpha-1 receptor agonist
clonidine
alpha-2 receptor agonist
dobutamine
beta-1 receptor agonist
terbutaline
beta-2 receptor agonist
isoproterenol
beta-1, beta-2 receptor agonist
phentolamine
alpha-2, alpha-2 receptor antagonist
propranolol
beta-1, beta-2 receptor antagonist
prazosine
alpha-1 receptor antagonist
yohimbine
alpha-2 receptor antagonist
metoprolol
beta-1 receptor antagonist
butoxamine
beta-2 receptor antagonist

note: tool only, there are no drugs on the market that block only beta-2
stimulates adrenergic receptors
alpha-1, alpha-2, beta-1, beta-2
epinephrine
stimulates alpha-1, alpha-2, & beta-1 receptors
norepinephrine
stimulates alpha-1 receptors
phenylephrine
stimulates alpha-2 receptors
slonidine
stimulates beta-1 receptors
dobutamine
stimulates beta-2 receptors
terbutaline
inhibits alpha-1 & alpha-2 receptors
phentolamine
inhibits beta-1 & beta-2
propranolol
inhibits alpha-1 receptors
prazosin
inhibits alpha-2 receptors
yohimbine
inhibits beta-1 receptors
metoprolol
inhibits beta-2 receptors
butoxamine
contraction of the radial muscle of the iris
alpha-1
relaxation of ciliary muscle
beta-2
increases heart rate of SA node
beta-1 (beta-2)
increase contractility of the atria
beta-1 (beta-2)
increases the velocity of the AV node
beta-1 (beta-2)
increases the velocity of the purkinje fibers
beta-1 (beta-2)
increases the velocity and contractility of the ventricles
beta-1 (beta-2)
constriction of the arterioles
alpha-1
dilation of the arterioles
beta-2
constriction of the veins
alpha
dilation of the veins
beta-2
relaxation of the tracheal & bronchial smooth muscles
beta-2
decreased secreation of the glands of the lungs
alpha-1
increased secretion of the glands of the lungs
alpha-2
decreased motility of the stomach
alpha-1, beta-2
increased constriction of the stomach sphincters
alpha-1
decreased hotility of the intestines
alpha, beta
increased constriction of the sphincters of the intestines
aplha
decreased secreations of the intestines
alpha-2
relaxation of the gall bladder
beta-2
decreased renin release by the kidneys
alpha-1
increased renin release by the kidneys
beta-1
relaxation of the detrusor muscle
beta-2
contration of the sphincter of the bladder
alpha-1
contraction of the uterus of a pregnant woman
alpha-1
relaxation of the uterus of a pregnant woman
beta-2
relaxation of the uterus of a non-pregnant woman
beta-2
ejaculation
alpha-1
contraction of the pilomotor of the skin
alpha-1
relaxation of the sweat glands
alpha-1
decreased secretion of the pancreatic acini
alpha
decreased secreation of the pancreatic beta cells
alpha-2
increased secretion of the pancreatic beta cells
beta-2
associated with negative feedback
alpha-2
associated with positive feedback
beta-2
What is the mechanism of action of indirect-acting cholinergic agonists?
inhibits cholinesterase, amplifying the action of endogenous acetylcholine (increases the concentration and half-life of acetylcholine in the synapses)