Pharm Exam 1 Drugs

Front 1

Name drugs for bacterial infections

Back 1

-Penicillin

-Cephalosporins

-Aminoglycosides

-Macrolides

-Tetracyclines

-Sulfonamides, trimethoprim and combination drug

-Fluroquinalones

-Anti-tubular drugs

-Vancomycin

Front 2

Cell wall synthesis inhibitor antibiotics?

Back 2

-Penicillins

-Cephalosporins

-Vancomycin

Front 3

Protein synthesis inhibitor antibiotics?

Back 3

-Aminoglycosides

-Macrolides

-Tetracyclines

Front 4

Metabolism inhibitor antibiotics?

Back 4

-Sulfonamides, trimethoprim and combination drugs

Front 5

DNA synthesis inhibitor antibiotics?

Back 5

Fluroquinalones

Front 6

Anti-tubercular drugs?

Back 6

1st Line

-isoniazid* (INH)

-rifampin

-ethambutol

Front 7

What are some anti-fungal drugs?

Back 7

-Polyenes

-amphotericin B

-nystatin

Front 8

What are some antiviral drugs? NRTI drugs?

Back 8

-Antiviral: Acyclovir

-NRTI: zidovudine

Front 9

What is the prototype of Penicillin?

Back 9

penicillin G

Front 10

What are some common drugs of Penicillin

Back 10

-Amoxicillin

-Amoxicillin/clavulanic acid

Front 11

What are some indications of penicillin?

Back 11

pneumonia

menigitis

skin, bone, and joint infections

Stomach infections

Blood and valve infections

Front 12

True or false

Penicillin can decrease the effects of oral contraceptives?

Back 12

True

Front 13

What are some adverse affects of Penicillin?

Back 13

Allergies and Anaphalaxis

Front 14

What is a prototype drug for Cephalosporins?

Back 14

cefazolin (Ancef, Kefzol)

Front 15

what Is a multi-generational drug?

Back 15

Cephalosporin

Front 16

What are some indications of Cephalosporins?

Back 16

-Lower respiratory track

-CNS systems

-GU systems

-Bones and Joints

Front 17

True or false

People who are allergic to Penicillin are not allergic to Cephalosporins

Back 17

FALSE (cross-sensitivity)

Front 18

What are some adverse affects of Cephalosporins?

Back 18

-Renal toxicity (Kidneys)

-Pseudomembranous colitis

Front 19

What is the protoype for vancomycin?

Back 19

Vancocin

Front 20

What are some indication of Vancomycin?

Back 20

-MRSA
-Pseduomembrannous colitis caused by c. diff

-Prophylaxis

Front 21

Which drug has a narrow therapeutic index?

Back 21

Vancomycin

Front 22

What are some adverse effects of Vancomycin?

Back 22

-Nephrotoxic
-Redman Syndrome

Front 23

What is the prototype for Aminoglycosides?

Back 23

gentaminicin (Garamycin)

Front 24

What are the indication of aminoglycosides?

Back 24

-systemic infection caused by aerboic gram-negative bacteria

-myobacteria

-some protozoans

Front 25

What are some adverse effects of aminoglycosides?

Back 25

Tinnitus or vertigo -> Ototoxicity (damaging to hearing)

-Nephrotoxicity

-Neuromuscular blockage

Front 26

What is the prototype for Macrolides?

Back 26

Erythromycin (Erythrocin)

Front 27

What are the indication of Macrolides?

Back 27

Penicillin substitute, whooping cough, legionnaires' disease and streptococcus infections

Front 28

What are some nursing implications of Macrolides?

Back 28

-Risk for drug interactions (finding out about herbal supplements)

-GI side affects so take w/ food

Front 29

What re some side affects of Macrolides?

Back 29

-Nausea, vomiting, diarrhea, loss of appetite, abdominal cramping, photosensitivity

Front 30

What is the prototype drug for Tetracyclines?

Back 30

Tetracycline (Sumycin)

Front 31

True or false

Tetracyclines is not a broad central antibiotic

Back 31

FALSE

Front 32

Nursing implications for tetracyclines

Back 32

-Do not give to children under 8

-Do not take with milk or iron (can decrease absorption)

Front 33

What are indications for tetracyclines?

Back 33

Lyme disease, mycoplasma & chlamydia, cholera, and rocky mountain spotted fever

Front 34

What are some adverse effects tetracyclines?

Back 34

Discoloration of teeth, photosensitivity, superinfections

Front 35

What is the prototype for sulfonmaides, trimethoprim and combination drugs?

Back 35

Bactrim

Front 36

What is the common drug for sulfonmaides, trimethoprim and combination drugs

Back 36

Trimethoprim/sufamethoxazole

Front 37

What are the indications for sulfonmaides, trimethoprim and combination drugs?

Back 37

UTIs, Shigellosis, toxoplasmosis, pneumocycitic carini, pneumonia

Front 38

What are the nursing implications for sulfonmaides, trimethoprim and combination drugs?

Back 38

-Notify HCP of any rash or fever develop for steven johnson syndrome

- Use sunscreen and protective clothes

-Monitor blood counts

Front 39

What are some adverse affects of sulfonmaides, trimethoprim and combination drugs?

Back 39

-Photosensitivity

-Suppression of bone marrow cell division

-Steven-Johnson syndrome

-fulminant hepatic necrosis

Front 40

What is the common drug for Fluroquinalones?

Back 40

Levofaxacin

Front 41

What are the indication for Fluroquinalones?

Back 41

respiratory infections, GI and GU infections, skin and soft tissue infections

Front 42

What are the nursing implications for Fluroquinalones?

Back 42

-Notify HCP if inflammation of tendon occurs

Front 43

Adverse effects of Fluroquinalones?

Back 43

-Tendon rupture

-Serious heart dysrhythmias

-neurotoxicity

-Peripheral neruopthay

Front 44

What is the prototype for anti-tuberculosis drugs?

Back 44

isoniazid

Front 45

Name the mechanism for each anti-tuberculosis drug?

Back 45

Isoniazid* & Ethambutol- cell wall synthesis

Rifampin- inhibits the enzymes needed for TB RNA and protein synthesis

Front 46

What are the side effects of each anti-tuberculosis drug?

Back 46

-Isoniazid; peripheral neuropathy

-Refampin: Reddish orange secretions

-Ethambutol: increase uric acid and cause optic neuritis

Front 47

What are some nursing implications for anti-tuberculosis drugs?

Back 47

-no alcohol or patient can be in risk for liver failure

Front 48

What is the adverse affect anti-tuberculosis drugs?

Back 48

Hepatoxicity

Front 49

What is the drug mechanism of Polyenes?

Back 49

Cell membrane inhibitor

Front 50

What is the prototype of each polyenes?

Back 50

amphotericin B: Fungizone

nystatin: Mycostatin

Front 51

What is the difference between amphtericin B vs Nysatatin?

Back 51

amphthericin B: Systemic

nystatin: Topical

Front 52

What are some nursing implcations for Polyenes?

Back 52

-Premeidcate with tynenol and benedryl

-Avoid concomitant nephrotoxic drugs

Front 53

What are some adverse effects of polyenes?

Back 53

highly nephrotoxic, creatinine, increase fluids

Front 54

What are some infusion reactions of polyenes?

Back 54

-fever

-chills

-rigor

-nausea

-headache "shake and bake"

Front 55

What is the prototype for Acyclovir?

Back 55

Zovirax

Front 56

What is the mechanism of action for Acyclovir?

Back 56

Interferes with virl DNA synthesis

Front 57

What is the idications for Acyclovir?

Back 57

herpes virus

Front 58

What is the adverse reaction of acyclovir?

Back 58

reduce kidney function, leading to kidney damage and failure

Front 59

What is the prototype for Nucleoside Reverse transcriptase inhibitor?

Back 59

zidovudine (AZT, Retrovir)

Front 60

True or False Nucleoside Reverse transcriptase inhibitor is part of HAART?

Back 60

True

Front 61

Nursing implications for Nucleoside Reverse transcriptase inhibitor?

Back 61

-Avoid fatty foods and fried foods

-Loss of sensation risk for injury

Front 62

What are some side effects of Nucleoside Reverse transcriptase inhibitor?

Back 62

Nausea, headach, GI upset w/fatty fried foods

Front 63

What are some adverse effects of Nucleoside Reverse transcriptase inhibitor?

Back 63

liver toxicity, peripheral neuropathy with long-term use